(2SR,3R,4R)-3,4-O-isopropylidene-1-nitrohex-5-ene-2,3,4-triol | 260416-35-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2SR,3R,4R)-3,4-O-isopropylidene-1-nitrohex-5-ene-2,3,4-triol
• 英文别名: 1-[(4S,5R)-5-ethenyl-2,2-dimethyl-1,3-dioxolan-4-yl]-2-nitroethanol
• CAS: 260416-35-1
• 化学式: C₉H₁₅NO₅
• 分子量: 217.222
• InChiKey: QXPRDNZOYSYCDF-VVXQKDJTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  84.5
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (2SR,3R,4R)-3,4-O-isopropylidene-1-nitrohex-5-ene-2,3,4-triol 在 4-甲基苯磺酸吡啶 、 异氰酸苯酯 、 三乙胺 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 144.0h， 生成 (3aS,4R,5R,6R)-6-(tetrahydropyran-2-yloxy)-4,5-isopropylidenedioxy-3a,4,5,6-tetrahydro-3H-cyclopent[c]isoxazole
  参考文献：
  名称：

  Diastereocontrol in the intramolecular cycloadditions of 2-substituted-erythro-3,4-isopropylidenedioxyhex-5-enenitrile oxides

  摘要：

  The influence of the 2-substituent on the diastereoselectivity of the intramolecular cycloadditions in a series of 2-substitute-erythro-3,4-isopropylidene-dioxyhex-5-enenitrile oxides, generated in situ from Selected sugar derivatives, was examined. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00991-6
• 作为产物：
  描述：

  methyl 5-deoxy-5-iodo-2,3-isopropylidene-β-D-ribofuranoside 在 sodium 、 锌 作用下， 以 乙醇 为溶剂， 反应 26.0h， 生成 (2SR,3R,4R)-3,4-O-isopropylidene-1-nitrohex-5-ene-2,3,4-triol
  参考文献：
  名称：

  Diastereocontrol in the intramolecular cycloadditions of 2-substituted-erythro-3,4-isopropylidenedioxyhex-5-enenitrile oxides

  摘要：

  The influence of the 2-substituent on the diastereoselectivity of the intramolecular cycloadditions in a series of 2-substitute-erythro-3,4-isopropylidene-dioxyhex-5-enenitrile oxides, generated in situ from Selected sugar derivatives, was examined. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00991-6

文献信息

• Diastereocontrol in the intramolecular cycloadditions of 2-substituted-erythro-3,4-isopropylidenedioxyhex-5-enenitrile oxides
  作者：John K. Gallos、Alexandros E. Koumbis、Vassiliki P. Xiraphaki、Constantinos C. Dellios、Evdoxia Coutouli-Argyropoulou

  DOI：10.1016/s0040-4020(99)00991-6

  日期：1999.12

  The influence of the 2-substituent on the diastereoselectivity of the intramolecular cycloadditions in a series of 2-substitute-erythro-3,4-isopropylidene-dioxyhex-5-enenitrile oxides, generated in situ from Selected sugar derivatives, was examined. (C) 1999 Elsevier Science Ltd. All rights reserved.