2-dipicolylamine-N-(quinolino-8-yl)acetamide | 1415145-11-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-dipicolylamine-N-(quinolino-8-yl)acetamide
• 英文别名: [zinc(2-dipicolylamine-N-(naphthalene-4-yl)acetamide(-H))(nitrate)](nitrate)
• CAS: 1415145-11-7
• 化学式: C₂₃H₂₂N₅O₂Zn*ClO₄
• 分子量: 565.301
• InChiKey: KQJJZVLUTUVVAI-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  zinc(II) perchlorate 、 2-[bis(pyridin-2-ylmethyl)]amino-N-quinolin-8-yl-acetamide 在 base 作用下， 以 水 、 乙腈 为溶剂， 生成 2-dipicolylamine-N-(quinolino-8-yl)acetamide
  参考文献：
  名称：

  Zinc selective chemosensors based on the flexible dipicolylamine and quinoline

  摘要：

  Zinc sensor molecules containing quinoline have been synthesized, which show fluorescence in the presence of Zn2+. The nitrogen in quinoline is critical to fluorescence and fluorescence enhancement is promoted by deprotonating the sensor's amide. One of the sensors is highly selective for Zn2+ over Cd2+ and other cations such as Hg2+, Fe2+, Mn2+ and Ca2+. This selectivity can be attributed to the increased absorption of the sensor in the presence of Zn2+ and the strong binding of Zn2+. Structural studies, including X-ray and NMR, show the ability of dipicolylamine (DPA) to bind in facial and meridional manners to Zn2+. Crystal structures of different compounds show Zn2+ coordinating to three, four, and five nitrogens from the compounds. They also indicate that the selectivity of DPA containing compounds towards Zn2+ may originate from Zn2+ being stable in different coordination environments. (C) 2012 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2012.09.009