(3S)-3-ethyl-3-methyl-4-butanolide | 80348-89-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: (3S)-3-ethyl-3-methyl-4-butanolide
• 英文别名: (4R)-4-ethyl-4-methyloxolan-2-one
• CAS: 80348-89-6
• 化学式: C₇H₁₂O₂
• 分子量: 128.171
• InChiKey: CHDAMWZEYINXCG-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (2R,4S)-(+)-2-methyl-4-(trityloxymethyl)-4-butanolide 在 盐酸 、 sodium periodate 、 lithium aluminium tetrahydride 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 甲醇 、 六甲基磷酰三胺 为溶剂， 生成 (3S)-3-ethyl-3-methyl-4-butanolide
  参考文献：
  名称：

  手性季碳的高立体选择性构建：β,β-二取代γ-丁内酯的不对称合成

  摘要：

  β, β-二取代 γ-丁内酯的不对称合成以高度立体选择性和可预测的方式进行，通过 (S) -γ-三苯甲基氧基甲基-γ-丁内酯的顺序二烷基化，然后内酯羰基转位。还描述了在合成螺环化合物中的应用。

  DOI：

  10.1246/cl.1981.1621

文献信息

• Stereoselective reactions. 14. Efficient enantioselective construction of quaternary carbon centers by the sequential dialkylation of (S)-.gamma.-[(trityloxy)methyl]-.gamma.-butyrolactone. Synthesis of optically active .beta.,.beta.-disubstituted .gamma.-butyrolactones
  作者：Kiyoshi Tomioka、Youn Sang Cho、Fuminori Sato、Kenji Koga

  DOI：10.1021/jo00252a039

  日期：1988.8
• (METH)ACRYLATE COMPOUND, (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20160347896A1

  公开（公告）日：2016-12-01

  The present invention provides a resist or a compound for use as a resist, which is highly sensitive and well-balanced without losing the fundamental physical properties required as a chemically amplified resist (e.g., resolution, line edge roughness (LER)). The present invention is directed to a (meth)acrylate compound represented by general formula (1) and a process for preparation thereof, as well as a (meth)acrylic copolymer obtainable by polymerization of the (meth)acrylate compound of general formula (1) and a photosensitive resin composition thereof: (wherein R 1 represents a hydrogen atom or a methyl group, R 2 represents a linear or branched alkyl group containing 2 to 4 carbon atoms, and each R 3 may be the same or different and represents a group represented by the following formula (2) or (3), etc.) (provided that formulae (2) and (3) are as defined in the specification of the present application).
• US9951163B2
  申请人：——

  公开号：US9951163B2

  公开（公告）日：2018-04-24