5-methoxy-dec-2t-enal | 64245-60-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-methoxy-dec-2t-enal
• 英文别名: (E)-5-methoxydec-2-enal
• CAS: 64245-60-9
• 化学式: C₁₁H₂₀O₂
• 分子量: 184.279
• InChiKey: UAMKBPJFNORBPD-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  己醛而甲基乙缩醛 、 1-(trimethylsiloxy)-1,3-butadiene 在 titanium(IV) isopropylate 、 四氯化钛 作用下， 以 二氯甲烷 为溶剂， 生成 5-methoxy-dec-2t-enal
  参考文献：
  名称：

  一种制备δ-烷氧基-α,β-不饱和醛和多烯醛的新方法

  摘要：

  二烯氧基硅烷 (2) 在 TiCl4 存在下以及 TiCl4 和 Ti(OiPr)4 共存下与缩醛反应，以良好的产率得到 δ-烷氧基-α,β-不饱和醛 (3-5)。在1,8-二氮杂双环[5.4.0]十一碳-7-烯或1,5-二氮杂双环[4.3.0]非5-烯和分子筛3A或4A存在下，δ-烷氧基的消除反应α,β-不饱和醛 (3-5) 的合成顺利进行，以良好的收率提供相应的多烯醛。

  DOI：

  10.1246/bcsj.50.1161

文献信息

• ISHIDA AKIHIKO; MUKAIYAMA TERUAKI, BULL. CHEM. SOC. JAP., 1977, 50, NO 5, 1161-1168
  作者：ISHIDA AKIHIKO、 MUKAIYAMA TERUAKI

  DOI：——

  日期：——
• COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION
  申请人：Ishida Kenya

  公开号：US20110117147A1

  公开（公告）日：2011-05-19

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from 1-menthol, 1-isopulegol, 3-(1-menthoxy)propan-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.
• US8632792B2
  申请人：——

  公开号：US8632792B2

  公开（公告）日：2014-01-21
• [EN] COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION<br/>[FR] COMPOSITION D'AGENT DE SENSATION DE FRAÎCHEUR ET COMPOSITION D'AGENT DE STIMULATION SENSORIELLE
  申请人：TAKASAGO PERFUMERY CO LTD

  公开号：WO2009123355A2

  公开（公告）日：2009-10-08

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from l-menthol, l-isopulegol, 3-(l-menthoxy)propan-1,2-diol, 2-(l-menthoxy)ethan-1-ol, 3-(l-menthoxy)propan-1-ol, 2-methyl-3-(l-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.
• A New Method for the Preparation of δ-Alkoxy-α,β-unsaturated Aldehydes and Polyenals
  作者：Akihiko Ishida、Teruaki Mukaiyama

  DOI：10.1246/bcsj.50.1161

  日期：1977.5

  TiCl4 and also in the coexistence of TiCl4 and Ti(OiPr)4 to give δ-alkoxy-α,β-unsaturated aldehydes (3–5) in good yields. In the presence of 1,8-diazabicyclo[5.4.0] undec-7-ene or 1,5-diazabicyclo[4.3.0]non-5-ene and molecular sieves 3A or 4A, the elimination reaction of δ-alkoxyl group of α,β-unsaturated aldehydes (3–5) proceeds smoothly to afford the corresponding polyenals in good yields.

  二烯氧基硅烷 (2) 在 TiCl4 存在下以及 TiCl4 和 Ti(OiPr)4 共存下与缩醛反应，以良好的产率得到 δ-烷氧基-α,β-不饱和醛 (3-5)。在1,8-二氮杂双环[5.4.0]十一碳-7-烯或1,5-二氮杂双环[4.3.0]非5-烯和分子筛3A或4A存在下，δ-烷氧基的消除反应α,β-不饱和醛 (3-5) 的合成顺利进行，以良好的收率提供相应的多烯醛。