thiazol-2-yl(p-tolyl)methanone | 1433782-05-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: thiazol-2-yl(p-tolyl)methanone
• 英文别名: (4-Methylphenyl)-(1,3-thiazol-2-yl)methanone
• CAS: 1433782-05-8
• 化学式: C₁₁H₉NOS
• 分子量: 203.265
• InChiKey: JJWBLXPOMOYSHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  58.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对甲基苯乙腈 在 palladium diacetate 、 三乙胺 、 cesium pivalate 作用下， 以 乙醇 为溶剂， 反应 44.0h， 生成 thiazol-2-yl(p-tolyl)methanone
  参考文献：
  名称：

  苯并唑衍生物的无金属需氧氧化†

  摘要：

  2-苄基苯并噻唑和苯并咪唑在空气和碱性条件下容易氧化，以高收率得到相应的酮。指某东西的用途醋酸钯 作为催化剂，收效甚微，甚至在某些情况下收率低得多。

  DOI：

  10.1039/c3ob27404g

文献信息

• A convenient synthesis of 2-acyl benzothiazoles/thiazoles from benzothiazole/thiazole and N,N'-carbonyldiimidazole activated carboxylic acids
  作者：Tonghui Huang、Xin Wu、Yongbo Yu、Lin An、Xiaoxing Yin

  DOI：10.1016/j.tetlet.2019.05.043

  日期：2019.6

  A convenient and efficient strategy for the synthesis of 2-acyl benzothiazoles/thiazoles has been developed. The treatment of benzothiazole/thiazole with allylic Grignard reagents readily generates the corresponding 2-Grignard reagents, which is followed by a reaction with N,N'-carbonyldiimidazole activated carboxylic acids to afford various 2-acyl benzothiazoles/thiazoles products. The synthetic method

  已经开发了一种方便有效的合成2-酰基苯并噻唑/噻唑的策略。用烯丙基格利雅试剂处理苯并噻唑/噻唑容易产生相应的2-格利雅试剂，然后与N，N′-羰基二咪唑活化的羧酸反应，得到各种2-酰基苯并噻唑/噻唑产物。该合成方法适用于多种羧酸，并且在温和的反应条件下，可以很容易地获得2-酰基苯并噻唑/噻唑。
• PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES
  申请人：Zambach Werner

  公开号：US20080200525A1

  公开（公告）日：2008-08-21

  Compounds of formula wherein A 0 , A 1 and A 2 are each independently of the others a bond or a C 1 -C 6 alkylene bridge; A 3 is a C 1 -C 6 alkylene bridge which is unsubstituted or substituted by from one to six identical or different substituents selected from halogen and C 3 -C 8 cycloalkyl; Y is, for example, O, S, SO or SO 2 ; M is O or NOR 6 , X 1 and X 2 are each independently of the other fluorine, chlorine or bromine; R 1 , R 2 and R 3 are, for example, H, halogen, OH, SH, CN, nitro, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkylcarbonyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl or C 2 -C 6 alkynyl; Q is, for example, O, S, SO or SO 2 ; W is, for example, O, S, SO, SO 2 , —C(═O)—O— or —O—C(═O)—; T is, for example, a bond, O, S, SO, SO 2 , —C(═O)—O— or —O—C(═O)—; D is CH or N; R 4 is, for example, H, halogen, OH, SH, CN, nitro, C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R 5 is, for example, C 1 -C 12 alkyl, C 3 -C 8 cycloalkyl or —N(R 7 ) 2 ; R 7 is H, C 1 -C 6 alkyl, C 1 -C 3 haloalkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 3 haloalkylcarbonyl, C 1 -C 6 alkoxycarbonyl, C 3 -C 8 cycloalkyl, C 3 -C 8 cycloalkylcarbonyl or formyl; k is 0, 1, 2, 3 or 4; m is 1 or 2; and q is 0, 1 or 2; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds and agrochemically acceptable salts thereof, and a process for the preparation of those compositions and their use, to plant propagation material treated with those compositions, and a method of controlling pests.

  该公式的化合物中，A0、A1和A2分别独立地是键或C1-C6烷基桥；A3是C1-C6烷基桥，未取代或取代为1-6个相同或不同的卤素和C3-C8环烷基的取代基；Y是例如O、S、SO或SO2；M是O或NOR6；X1和X2各自独立地是氟、氯或溴；R1、R2和R3是例如H、卤素、OH、SH、CN、硝基、C1-C6烷基、C1-C6卤代烷基、C1-C6烷基羰基、C2-C6烯基、C2-C6卤代烯基或C2-C6炔基；Q是例如O、S、SO或SO2；W是例如O、S、SO、SO2、-C（═O）-O-或-O-C（═O）-；T是例如键、O、S、SO、SO2、-C（═O）-O-或-O-C（═O）-；D是CH或N；R4是例如H、卤素、OH、SH、CN、硝基、C1-C6烷基或C1-C6卤代烷基；R5是例如C1-C12烷基、C3-C8环烷基或-N（R7）2；R7是H、C1-C6烷基、C1-C3卤代烷基、C1-C6烷基羰基、C1-C3卤代烷基羰基、C1-C6烷氧羰基、C3-C8环烷基、C3-C8环烷基羰基或甲酰基；k是0、1、2、3或4；m是1或2；q是0、1或2；如适用，其可能的E/Z异构体、E/Z异构体混合物和/或互变异构体，在自由形式或盐形式中，以及制备这些化合物的方法、选择这些化合物为活性成分的杀虫剂组合物和农用化学品可接受的盐的使用、制备这些组合物的方法和使用这些组合物处理植物繁殖材料、以及控制害虫的方法。
• ELECTRONIC CONTROL OF TRANSMITTANCE OF VISIBLE AND NEAR-INFRARED RADIATION
  申请人：Kebotix, Inc.

  公开号：US20220403229A1

  公开（公告）日：2022-12-22

  The present invention generally relates to optoelectronic compounds, including certain nitrobenzoyl compounds, for example 2-(4-nitrobenzoyl)oxazole. In certain embodiments, these compounds can be used as electrochromic media in devices requiring change of optical absorbance or transmittance as a function of applied voltage. Examples of such devices include electrochromic mirrors, windows, displays, or the like. One specific example is solar and thermal control by smart, dynamic windows for energy-efficient buildings. Other embodiments of the invention are generally directed to systems and devices using such compounds, methods of using such compounds, e.g., to control the absorbance or transmittance of light, kits involving such compounds, or the like.
• US7569727B2
  申请人：——

  公开号：US7569727B2

  公开（公告）日：2009-08-04
• Metal-free aerobic oxidation of benzazole derivatives
  作者：Aurélie Dos Santos、Laurent El Kaïm、Laurence Grimaud

  DOI：10.1039/c3ob27404g

  日期：——

  2-Benzyl benzothiazoles and benzimidazoles are easily oxidized under air and basic conditions to give the corresponding ketones in good yields. The use of palladium acetate as a catalyst has little effect and even gives, in some cases, much lower yields.

  2-苄基苯并噻唑和苯并咪唑在空气和碱性条件下容易氧化，以高收率得到相应的酮。指某东西的用途醋酸钯 作为催化剂，收效甚微，甚至在某些情况下收率低得多。