1-(2-氯-4-羟基-3-甲氧基苯基)乙酮 | 151340-06-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-(2-氯-4-羟基-3-甲氧基苯基)乙酮
• 英文名称: 2-chloroacetoguaiacone
• 英文别名: 1-(2-Chloro-4-hydroxy-3-methoxyphenyl)ethanone
• CAS: 151340-06-6
• 化学式: C₉H₉ClO₃
• 分子量: 200.622
• InChiKey: SIDFBARFEDLRPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氯-3-甲氧基-4-羟基苯甲醛 在 sodium methylate 作用下， 以 吡啶 、 甲醇 、 乙醚 为溶剂， 反应 67.0h， 生成 1-(2-氯-4-羟基-3-甲氧基苯基)乙酮
  参考文献：
  名称：

  Preparation and properties of chlorinated syringic acids, acetosyringones, acetoguaiacones and methoxy-p-hydroquinones — components of pulp bleaching effluents

  摘要：

  A range of chlorinated phenols which serve as standards for compounds occurring in effluents from the bleaching of wood pulps with chlorine-containing reagents has been prepared. The chlorinated phenols include chlorosyringic acids, chloroacetosyringones, chloroacetoguaiacones, 5-chloro-2-methoxy-p-hydroquinone and chloro-2,6-dimethoxy-p-hydroquinones. With the exception of the ring-chlorinated acetoguaiacones which were prepared by reaction of chlorovanillin acetates with diazomethane, the compounds were obtained by direct chlorination of appropriate phenols or their acetates. Gas chromatographic and mass spectrometric data for the acetylated phenols are given.

  DOI：

  10.1016/0045-6535(94)00377-7

文献信息

• Preparation and properties of chlorinated syringic acids, acetosyringones, acetoguaiacones and methoxy-p-hydroquinones — components of pulp bleaching effluents
  作者：Terrence J. Smith、Ross H. Wearne、Adrian F.A. Wallis

  DOI：10.1016/0045-6535(94)00377-7

  日期：1995.1

  A range of chlorinated phenols which serve as standards for compounds occurring in effluents from the bleaching of wood pulps with chlorine-containing reagents has been prepared. The chlorinated phenols include chlorosyringic acids, chloroacetosyringones, chloroacetoguaiacones, 5-chloro-2-methoxy-p-hydroquinone and chloro-2,6-dimethoxy-p-hydroquinones. With the exception of the ring-chlorinated acetoguaiacones which were prepared by reaction of chlorovanillin acetates with diazomethane, the compounds were obtained by direct chlorination of appropriate phenols or their acetates. Gas chromatographic and mass spectrometric data for the acetylated phenols are given.