4-(4-Methoxyphenyl)-1,5-dimethylimidazole | 890705-57-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(4-Methoxyphenyl)-1,5-dimethylimidazole
• 英文别名: 4-(4-methoxyphenyl)-1,5-dimethylimidazole
• CAS: 890705-57-4
• 化学式: C₁₂H₁₄N₂O
• 分子量: 202.256
• InChiKey: WAERROWIJYGCLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  27
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(4-Methoxyphenyl)-1,5-dimethylimidazole 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以50%的产率得到2-Bromo-4-(4-methoxy-phenyl)-1,5-dimethyl-1H-imidazole
  参考文献：
  名称：

  Shape-Selective Fluorescent Sensing Ensemble Using a Tweezer-Type Metalloreceptor

  摘要：

  A fluorescent sensing ensemble for pyridine-derived compounds is described. The receptor portion of the ensemble is prepared from a bisimidazole pyridine which coordinates copper to form a well-defined cavity. Small heteroaromatic guests such as adenine bind strongly in the cavity. The fluorescent response is provided by a dye which is coordinated to the receptor and quenched by the metal ion. The dye is released upon guest binding providing up to 25-fold fluorescence increases.

  DOI：

  10.1021/ol060641k
• 作为产物：
  描述：

  N-ethylidenemethylamine 、 Alpha-对甲苯磺酰基（4-甲氧基-苄基）异腈 在 potassium carbonate 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 以425 mg的产率得到4-(4-Methoxyphenyl)-1,5-dimethylimidazole
  参考文献：
  名称：

  Shape-Selective Fluorescent Sensing Ensemble Using a Tweezer-Type Metalloreceptor

  摘要：

  A fluorescent sensing ensemble for pyridine-derived compounds is described. The receptor portion of the ensemble is prepared from a bisimidazole pyridine which coordinates copper to form a well-defined cavity. Small heteroaromatic guests such as adenine bind strongly in the cavity. The fluorescent response is provided by a dye which is coordinated to the receptor and quenched by the metal ion. The dye is released upon guest binding providing up to 25-fold fluorescence increases.

  DOI：

  10.1021/ol060641k