(+/-)-1-Chlor-5-methoxy-hexan | 818-73-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (+/-)-1-Chlor-5-methoxy-hexan
• 英文别名: 1-chloro-5-methoxy-hexane；1-Chloro-5-methoxyhexane
• CAS: 818-73-5
• 化学式: C₇H₁₅ClO
• mdl: MFCD19235211
• 分子量: 150.649
• InChiKey: WYYDAGMLLUWISC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (+/-)-1-Chlor-5-methoxy-hexan 在 吡啶 、 氯化亚砜 作用下， 生成 (+/-)-1-Chlor-6-methoxy-heptan
  参考文献：
  名称：

  Michel,C.; Tchelitcheff,S., Bulletin de la Societe Chimique de France, 1964, p. 2230 - 2231

  摘要：

  DOI：
• 作为产物：
  描述：

  4-甲氧基戊烷-1-醇 在 吡啶 、 氯化亚砜 作用下， 生成 (+/-)-1-Chlor-5-methoxy-hexan
  参考文献：
  名称：

  Michel,C.; Tchelitcheff,S., Bulletin de la Societe Chimique de France, 1964, p. 2230 - 2231

  摘要：

  DOI：

文献信息

• Pyridopyrimidine compounds and their uses
  申请人：——

  公开号：US20040023995A1

  公开（公告）日：2004-02-05

  Novel pyridopyrimidine-based compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

  小说嘧啶并[3,4-d]吡啶基化合物被发现可用于治疗或预防因细胞因子内部信号传导受到影响而引起的疾病或障碍的症状或表现。
• US6825180B2
  申请人：——

  公开号：US6825180B2

  公开（公告）日：2004-11-30
• [EN] PYRIDOPYRIMIDINE COMPOUNDS AND THEIR USES<br/>[FR] COMPOSES DE PYRIDOPYRIMIDINE ET LEURS UTILISATIONS
  申请人：CELL THERAPEUTICS INC

  公开号：WO2002094824A1

  公开（公告）日：2002-11-28

  Novel pyridopyrimidine-based compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling, having the following formula: formula (I) wherein R1 is selected from a member of the group consisting of hydrogen, hydroxyl, methoxyl, N-OH, acylamino group, cyano group, sulfo, sulfonyl, sulfinyl, sulfhydryl (mercapto), sulfeno, sulfanilyl, sulfamyl, sulfamino, and phosphino, phosphinyl, phospho phosphono and -NRaRb, wherein each of Ra and Rb may be the same or different and each is selected from the group consisting of hydrogen and optionally substituted: C(1-20)alkyl, C(1-20)cycloalkyl, C(1-20)alkenyl, C(1-20)cycloalkenyl, C(1-20)alkynyl, aryl, heteroaryl, and heterocyclic group. R2 and R3 are independently selected from a member of the group consisting of halo, thio, oxo, C(1-20)alkyl, C(1-20)hydroxyalkyl, C(1-20)thioalkyl, C(1-20)alkylthio, C(1-20)alkylamino, C(1-20)alkylaminoalkyl, C(1-20)aminoalkyl, C(1-20)aminoalkoxyalkenyl, C(1-20)aminoalkoxyalkynyl, C(1-20)diaminoalkyl, C(1-20)triaminoalkyl, C(1-20)tetraaminoalkyl, C(1-20)aminotrialkoxyamino, C(1-20)alkylamido, C(1-20)alkylamidoalkyl, C(1-20)amidoalkyl, C(1-20)acetamidoalkyl, C(1-20)alkenyl, C(1-20)alkynyl, C(1-20)alkoxyl, C(1-20)alkoxyalkyl, C(1-20)dialkoxyalkyl, and NraRb. R4 may be hydrogen or an optionally substituted member of the group consisting of C(1-20)alkyl, C(1-20)cycloalkyl, C(1-20)alkenyl, C(1-20)cycloalkenyl, C(1-20)alkynyl, aryl, heteroaryl, and heterocyclic group.
• Michel,C.; Tchelitcheff,S., Bulletin de la Societe Chimique de France, 1964, p. 2230 - 2231
  作者：Michel,C.、Tchelitcheff,S.

  DOI：——

  日期：——