(tri-O-acetyl-2-acetylamino-2-deoxy-α-D-glucopyranosyl)-(tetra-O-acetyl-α-D-glucopyranoside) | 20318-81-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (tri-O-acetyl-2-acetylamino-2-deoxy-α-D-glucopyranosyl)-(tetra-O-acetyl-α-D-glucopyranoside)
• 英文别名: (Tri-O-acetyl-2-acetylamino-2-desoxy-α-D-glucopyranosyl)-(tetra-O-acetyl-α-D-glucopyranosid)
• CAS: 20318-81-4
• 化学式: C₂₈H₃₉NO₁₈
• 分子量: 677.614
• InChiKey: GGFGFOOCFJUAFT-LBGIPDOESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.26
• 重原子数：
  47.0
• 可旋转键数：
  12.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  240.89
• 氢给体数：
  1.0
• 氢受体数：
  18.0

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium acetate 、 乙酸酐 作用下， 生成 (tri-O-acetyl-2-acetylamino-2-deoxy-α-D-glucopyranosyl)-(tetra-O-acetyl-α-D-glucopyranoside)
  参考文献：
  名称：

  Arcamone; Bizioli, Gazzetta Chimica Italiana, 1957, vol. 87, p. 896,901

  摘要：

  DOI：

文献信息

• The Synthesis of α-D-Galactopyranosyl and α-D-Mannopyranosyl 2-Amino-2-deoxy-α-D-glucopyranosides and the Conformation of Their Glycoside Linkage
  作者：Shinkiti Koto、Shigeru Inada、Shonosuke Zen

  DOI：10.1246/bcsj.54.2728

  日期：1981.9

  trehalosamine, α-D-galactopyranosyl 2-amino-2-deoxy-α-D-glucopyranoside, was synthesized by the glycosylation of 2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-galactopyranose with 3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide, using silver perchlorate and tribenzylamine in benzene, followed by chromatographic separation and the subsequent removal of the protecting groups. Similarly, α-D-mannopyranosyl

  海藻胺的新类似物α-D-吡喃半乳糖基2-氨基-2-脱氧-α-D-吡喃葡萄糖苷通过2,3,4,6-四-O-(对氯苄基)-α的糖基化合成-D-吡喃半乳糖与 3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilinino)-α-D-glupyranosyl bromide，在苯中使用高氯酸银和三苄胺，然后进行色谱分离以及随后去除保护基团。类似地，合成了α-D-吡喃甘露糖基2-氨基-2-脱氧-α-D-吡喃葡萄糖苷。这些 α,α-二糖的糖苷键的构象与它们异头碳的 13C 化学位移有关。