dihex-2-en-1-yl ether | 1277102-07-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: dihex-2-en-1-yl ether
• 英文别名: 1-Hex-2-enoxyhex-2-ene
• CAS: 1277102-07-4
• 化学式: C₁₂H₂₂O
• 分子量: 182.306
• InChiKey: ZKFNGAWFXQGLAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  反式-2-已烯-1-醇 在 二(三苯基膦)环戊二烯基氯化钌(II) 、 silver(I) 4-methylbenzenesulfonate 、 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 6.0h， 生成 dihex-2-en-1-yl ether
  参考文献：
  名称：

  [RuCp（PP）] +催化剂进行烯丙基化反应的范围：改变亲核试剂或烯丙醇

  摘要：

  以烯丙醇为烯丙基供体与[RuCp（PP）] +进行的脱水烯丙基化反应的范围配合物作为催化剂的研究。脂肪醇已成功地与烯丙醇或二烯丙基醚烯丙基化，从而获得了对烷基烯丙基醚的高选择性。脂族醇的反应性为伯>仲secondary叔。在没有强酸的情况下，叔醇1-金刚烷醇的反应非常缓慢，但是当加入HOT时，可以获得合理的1-金刚烷基烯丙基醚的收率。发现烷基烯丙基醚是相对于二烯丙基醚是热力学上有利的产物。除了醇以外，硫醇和吲哚也被有效地烯丙基化，而苯胺则充当催化剂抑制剂。与各种取代的烯丙基醇的烯丙基化反应得到具有取代模式保留的产物。有人认为，Ru（IV）σ-烯丙基物质在这些烯丙基化反应的机理中起着关键作用。版权所有©2010 John Wiley＆Sons，Ltd.

  DOI：

  10.1002/aoc.1744

文献信息

• [EN] AMINE-CONTAINING CYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME<br/>[FR] HYDROFLUOROÉTHERS CYCLIQUES CONTENANT UNE AMINE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2017155735A1

  公开（公告）日：2017-09-14

  Described herein is a cyclic fluorinated compound of formula (I) where: L is O, CH2, or a covalent bond; X is selected from F or CF3, and Y is selected from H, F, or CF3, wherein when X is CF3 then Y is F and when Y is CF3 then X is F„ each Rf1 is independently selected from a linear or branched perfluorinated alkyl group comprising 1-8 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof; or the two Rf1 groups are bonded together to form a fluorinated ring structure comprising 4-8 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof; the -CFZ-CHAQ group is bonded to a ring carbon that is alpha to at least one O atom of the ring; A is selected from F, or CF3; Z is selected from H, F, or CF3; and Q is selected from (i) a F atom, (ii) a Cl atom, (iii) a linear, cyclic, or branched perfluorinated alkyl group comprising 1-8 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof, or (iv) a G(Rf2)e group, where G is an O atom or a N atom wherein: when Q is a Cl atom, then Z and A are F atoms; when G is O then e is 1, Z is H, F, or CF3; A is F; and Rf2 is a linear or branched perfluorinated alkyl group comprising 1-10 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof; when G is N then e is 2, and each Rf2 group is independently a linear or branched perfluorinated alkyl group comprising 1-8 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof or the two Rf2 groups are bonded together to form a fluorinated ring structure comprising 4-8 carbon atoms and optionally comprising at least one catenated atom selected from O, N, or combinations thereof, with the proviso that when A is CF3 then Z is F, and when Z is CF3 then A is F.

  本文描述的是一个循环氟化合物，其化学式为(I)，其中：L为O、CH2或共价键；X从F或CF3中选择，Y从H、F或 中选择，当X为 时，Y为F，当Y为 时，X为F；每个Rf1独立地选择自由1-8个碳原子的线性或支链全氟烷基基团，并且可选地包含至少一个由O、N或其组合选择的连结原子；或两个Rf1基团结合在一起形成含有4-8个碳原子并且可选地包含至少一个由O、N或其组合选择的连结原子的氟化环结构；-CFZ-CHAQ基团与环的至少一个O原子的α位碳原子结合；A从F或 中选择；Z从H、F或 中选择；Q从(i)F原子、(ii)Cl原子、(iii)线性、环状或支链全氟烷基基团，包括1-8个碳原子，并且可选地包含至少一个由O、N或其组合选择的连结原子，或(iv)G(Rf2)e基团中选择，其中G为O原子或N原子，当Q为Cl原子时，Z和A为F原子；当G为O时，e为1，Z为H、F或 ，A为F，Rf2为包括1-10个碳原子的线性或支链全氟烷基基团，并且可选地包含至少一个由O、N或其组合选择的连结原子；当G为N时，e为2，每个Rf2基团独立地选择自由1-8个碳原子的线性或支链全氟烷基基团，并且可选地包含至少一个由O、N或其组合选择的连结原子，或两个Rf2基团结合在一起形成含有4-8个碳原子并且可选地包含至少一个由O、N或其组合选择的连结原子的氟化环结构，但A为 时，Z为F，Z为 时，A为F。
• [EN] BRANCHED PERFLUOROVINYL ETHER COMPOUNDS, METHODS OF MAKING THE SAME, AND FLUOROPOLYMERS DERIVED FROM THE BRANCHED PERFLUOROVINYL ETHER COMPOUNDS<br/>[FR] COMPOSÉS D'ÉTHER DE PERFLUOROVINYLE RAMIFIÉ, LEURS PROCÉDÉS DE FABRICATION, ET FLUOROPOLYMÈRES DÉRIVÉS DES COMPOSÉS D'ÉTHER DE PERFLUOROVINYLE RAMIFIÉ
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2020044232A1

  公开（公告）日：2020-03-05

  Described herein is method of making branched perfluorinated compounds, specifically (CF3)2CFCF(CF3)OCF(CF3)C(=O)F and (CF3)2CFCF(CF3)OCF=CF2. Also disclosed herein is a fluoropolymer derived from the branched perfluorovinyl ether monomer and methods of making the fluoropolymer.

  本文描述了制备分支全氟化合物的方法，具体包括(CF3)2CFCF( )OCF( )C(=O)F和( )2CFCF( )OCF=CF2。本文还披露了从分支全氟乙烯醚单体衍生的氟聚合物及其制备方法。
• [EN] AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME<br/>[FR] HYDROFLUOROÉTHERS ACYCLIQUES AMINÉS ET LEURS PROCÉDÉS D'UTILISATION
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2017155686A1

  公开（公告）日：2017-09-14

  An acyclic fluorinated compound of formula (I) is amine -containing acyclic hydrofluoroethers. The acyclic fluorinated compound is useful as heat transfer, solvent cleaning, fire extinguishing agents and electrolyte solvents and additives.

  一种无环氟化合物，化学式为(I)，是含胺的无环氢氟醚。该无环氟化合物可用作传热剂、溶剂清洗剂、灭火剂和电解质溶剂和添加剂。
• [EN] HYDROXY-FUNCTIONALIZED TRIAZINE COMPOUNDS. CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING SUCH COMPOUNDS AND CURED ARTICLES THEREFROM<br/>[FR] COMPOSÉS DE TRIAZINE À FONCTION HYDROXY, COMPOSITIONS FLUOROPOLYMÈRES DURCISSABLES COMPRENANT DE TELS COMPOSÉS ET ARTICLES DURCIS OBTENUS À PARTIR DE CELLES-CI
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2020261088A1

  公开（公告）日：2020-12-30

  Described herein are compounds according to Formula (I) wherein each Rf is independently selected from a perfluorinated divalent group comprising 2 to 12 carbon atoms; and m is an integer independently selected from 1 to 3. A method of making the compound from a hydroxy-containing vinyl ether and excess ammonia is disclosed. In one embodiment, the hydroxy-ftmctionalized triazine compound is used in a curable fluoropolymer composition and cured to form articles.

  本文描述了符合公式（I）的化合物，其中每个Rf独立地选自包含2至12个碳原子的全氟双价基团；而m是独立地选自1至3的整数。还公开了一种通过含羟基的乙烯醚和过量氨制备该化合物的方法。在一种实施例中，羟基功能化三嗪化合物用于可固化的氟聚合物组合物中，并经过固化形成物品。
• LIGANDS FOR IMAGING CARDIAC INNERVATION
  申请人：Purohit Ajay

  公开号：US20100221182A1

  公开（公告）日：2010-09-02

  Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with 18 F in a variety of positions: aryl, alkyl, a keto, benzylic, beta-alkylethers, gamma-propylalkylethers and beta-proplylalkylethers. Alternatively or additionally, a methyl group a is added to the amine, and/or the catechol functionality is either eliminated or masked as a way of making these compounds more stable.

  本发明揭示了一种新型化合物，可用作核医学应用（PET成像）中的成像剂，用于成像心脏神经。这些基于PET的放射性示踪剂可能表现出增加的稳定性，减少NE释放（从而减少副作用），改善定量数据和/或高亲和力，以VMAT优于先前的放射性示踪剂。还提供了使用这些化合物成像心脏神经的方法。在某些情况下，这些化合物是通过在各种位置上衍生化某些化合物与18F而开发出来的：芳基，烷基，酮，苄基，β-烷基醚，γ-丙基烷基醚和β-丙基烷基醚。或者，还可以添加甲基基团到胺中，和/或消除或掩盖儿茶酚的功能，以使这些化合物更加稳定。