1-methyl-3-acetoxyadamantane | 38381-81-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-methyl-3-acetoxyadamantane
• 英文别名: methyl 3-methyladamantane-1-carboxylate；3-Methyl-adamantan-carbonsaeure-(1)-methylester；1-Methyladamantankarbonsaeuremethylester-3
• CAS: 38381-81-6
• 化学式: C₁₃H₂₀O₂
• 分子量: 208.301
• InChiKey: LTXCTBUWNQXMSZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methyl-3-acetoxyadamantane 在 aluminium(III) triflate 、 草酰氯 、 IF₅-5CH₂Cl₂ 、 Et₂O-10HF 、 sodium hydride 、 sodium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 乙醚 、 二氯甲烷 、 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 、 paraffin oil 为溶剂， 反应 52.5h， 生成 N-[(-)-2,10-camphorsulfonyl]-(1R,3S,5R,7S)-3-fluoro-5-methyladamantane-1-carboxyamide
  参考文献：
  名称：

  的合成光学活性fluoroadamantane衍生物具有在其不同的取代基叔β-碳和其作为非外消旋的源，用于新的光学活性金刚烷衍生物的使用

  摘要：

  通过分离其外消旋物获得对映体纯的3-氟-5-甲基金刚烷-1-甲酸甲酯，其外消旋物由三步法由甲基金刚烷-1-羧酸酯制备，总产率为86％。由所得的纯对映异构体，通过用苯基取代氟原子，制备了新的光学活性的金刚烷化合物。还制备了3-氨基-5-甲基金刚烷-1-羰氧基酸的两种对映体。

  DOI：

  10.1016/j.tet.2013.10.005
• 作为产物：
  描述：

  1-methyladamantane 在 硫酸 、 boron trifluoride methanol complex 作用下， 以 叔丁醇 为溶剂， 生成 1-methyl-3-acetoxyadamantane
  参考文献：
  名称：

  Koch,H.; Franken,J., Chemische Berichte, 1963, vol. 96, p. 213 - 219

  摘要：

  DOI：

文献信息

• Direct Fluorination of Adamantanes with Iodine Pentafluoride
  作者：Shoji Hara、Motoshi Aoyama

  DOI：10.1055/s-2008-1067205

  日期：2008.8

  Direct fluorination of adamantanes was achieved by iodine pentafluoride and one or two fluorine atoms were introduced selectively on the tertiary carbons of adamantanes.

  金刚烷的直接氟化是通过五氟化碘实现的，并在金刚烷的叔碳上选择性地引入一个或两个氟原子。
• RADIATION-SENSITIVE RESIN COMPOSITION
  申请人：JSR Corporation

  公开号：EP1602975A1

  公开（公告）日：2005-12-07

  A radiation-sensitive resin composition comprising an acid-labile group-containing resin obtained by living radical polymerization having a specific structure which is insoluble or scarcely soluble in alkali, but becomes alkali soluble by the action of an acid, and a photoacid generator, wherein the ratio of weight average molecular weight to number average molecular weight (weight average molecular weight/number average molecular weight) of the acid-labile group-containing-resin is smaller than 1.5.

  一种辐射敏感树脂组合物，包括一种通过活自由基聚合获得的具有特定结构的含酸基团树脂，该树脂不溶于碱或几乎不溶于碱，但在酸的作用下可溶于碱，还包括一种光酸发生器，其中含酸基团树脂的重量平均分子量与数量平均分子量之比（重量平均分子量/数量平均分子量）小于 1.5。
• FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION
  申请人：JSR Corporation

  公开号：EP2003148A2

  公开（公告）日：2008-12-17

  An object of the present invention is to provide a novel fluorine-containing polymer, a radiation-sensitive resin composition for liquid immersion lithography which contains the fluorine-containing polymer, which leads to a pattern having an excellent shape and excellent depth of focus, wherein the amount of an eluted component in a liquid for liquid immersion lithography such as water that comes in contact with the resist during exposure in liquid immersion lithography is little, and which provides a larger receding contact angle between the resist film and the liquid for liquid immersion lithography such as water, and a method for purifying the fluorine-containing polymer. The present resin composition comprises a novel fluorine-containing polymer (A) containing repeating units represented by the general formulae (1) and (2) and having Mw of 1,000-50,000, a resin (B) having an acid-unstable group, a radiation-sensitive acid generator (C), a nitrogen-containing compound (D) and a solvent (E).

  本发明的目的是提供一种新型含氟聚合物、一种用于液浸光刻的辐射敏感树脂组合物，该组合物含有该含氟聚合物，可使图案具有极佳的形状和极佳的焦深、其中，在液浸光刻过程中，液浸光刻用液体（如水）中与光刻胶接触的被洗脱成分的量很少，而且光刻胶膜与液浸光刻用液体（如水）之间的后退接触角较大；以及一种纯化含氟聚合物的方法。本树脂组合物包括含有通式（1）和（2）表示的重复单元且 Mw 为 1,000-50,000 的新型含氟聚合物（A）、具有酸不稳定基团的树脂（B）、辐射敏感酸发生器（C）、含氮化合物（D）和溶剂（E）。
• Fluorine-containing polymer, purification method, and radiation-sensitive resin composition
  申请人：JSR CORPORATION

  公开号：US10082733B2

  公开（公告）日：2018-09-25

  An object of the present invention is to provide a novel fluorine-containing polymer, a radiation-sensitive resin composition for liquid immersion lithography which contains the fluorine-containing polymer, which leads to a pattern having an excellent shape and excellent depth of focus, wherein the amount of an eluted component in a liquid for liquid immersion lithography such as water that comes in contact with the resist during exposure in liquid immersion lithography is little, and which provides a larger receding contact angle between the resist film and the liquid for liquid immersion lithography such as water, and a method for purifying the fluorine-containing polymer. The present resin composition comprises a novel fluorine-containing polymer (A) containing repeating units represented by the general formulae (1) and (2) and having Mw of 1,000-50,000, a resin (B) having an acid-unstable group, a radiation-sensitive acid generator (C), a nitrogen-containing compound (D) and a solvent (E).

  本发明的目的是提供一种新型含氟聚合物、一种用于液浸光刻的辐射敏感树脂组合物，该组合物含有该含氟聚合物，可使图案具有极佳的形状和极佳的焦深、其中，在液浸光刻过程中，液浸光刻用液体（如水）中与光刻胶接触的被洗脱成分的量很少，而且光刻胶膜与液浸光刻用液体（如水）之间的后退接触角较大；以及一种纯化含氟聚合物的方法。本树脂组合物包括含有通式（1）和（2）表示的重复单元且 Mw 为 1,000-50,000 的新型含氟聚合物（A）、具有酸不稳定基团的树脂（B）、辐射敏感酸发生器（C）、含氮化合物（D）和溶剂（E）。
• Synthesis of functionalized adamantanes from fluoroadamantanes
  作者：Motoshi Aoyama、Shoji Hara

  DOI：10.1016/j.tet.2009.02.059

  日期：2009.5

  Selective introduction of functional groups on the tert-carbon of adamantane was performed by substitution with fluorides. A methyl, phenacyl, aryl, cyclohexyl, alkoxy, or azido group was introduced into the adamantane skeleton without influencing the other functional groups present. Various functionalized adamantanes were synthesized using this scheme. A fluorinated analog of memantine (3-fluoro-5,7-dimethyl-1-adamantylammoniurn acetate 25) was synthesized from methyl 3,5-dimethyladamantane-1-carboxylate 6. (C) 2009 Elsevier Ltd. All rights reserved.