(Z)-hept-4-en-3-ol | 35077-66-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (Z)-hept-4-en-3-ol
• 英文别名: cis-4-hepten-3-ol；hept-4c-en-3-ol；cis-5-Oxyhepten-3
• CAS: 35077-66-8
• 化学式: C₇H₁₄O
• 分子量: 114.188
• InChiKey: VOGZQUBNQCQGNN-WAYWQWQTSA-N

物化性质

• 沸点：
  159.4±8.0 °C(Predicted)
• 密度：
  0.842±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-hept-4-en-3-ol 在 sodium hydroxide 作用下， 以 1,4-二氧六环 为溶剂， 生成 syn-2-ethyl-3-methyl-succinic acid
  参考文献：
  名称：

  Sucrow,W.; Richter,W., Chemische Berichte, 1971, vol. 104, p. 3679 - 3682

  摘要：

  DOI：
• 作为产物：
  描述：

  trimethyl-((Z)-1-propyl-but-1-enyl)-silane 生成 (Z)-hept-4-en-3-ol
  参考文献：
  名称：

  Regiospecific photosensitized oxygenation of vinylsilanes. A method for converting saturated ketones to 1,2-transposed allylic alcohols. Possible role of silicon in directing the regioselectivity of epoxysilane cleavage reactions

  摘要：

  DOI：

  10.1021/ja00509a084

文献信息

• The use of rieke zinc metal in the selective reduction of alkynes
  作者：Whe-Narn Chou、David L. Clark、James B. White

  DOI：10.1016/s0040-4039(00)92612-1

  日期：1991.1

  Rieke zinc has been found to be a very selective reducing agent of alkynes to cis-alkenes, allowing for the reduction of enynes to 1,3-dienes, diynes to enynes or dienes, and of propargylic alcohols to cis-allylic

  已发现Rieke锌是炔烃至顺式烯烃的非常选择性的还原剂，可将烯炔还原为1,3-二烯，将二炔还原为烯炔或二烯，并将炔丙醇还原为顺式烯丙基
• Process for production of triprenyl phenol compounds
  申请人：Tokyo University of Agriculture and Technology TLO Co., Ltd.

  公开号：EP2508611A1

  公开（公告）日：2012-10-10

  The present invention provides a triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), R1 represents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; R4 in the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents -CHY-(CH3)2Z; and Y and Z are respectively -H or -OH or together form a single bond: (III-1) wherein R5 represents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.

  本发明提供了由下式(II)和(III)表示的具有溶栓增强活性的三烯丙基酚化合物，以及生产该三烯丙基酚化合物的有效方法。在通式（II）和（III）中，R1 代表芳香基团，该芳香基团具有至少一个从羧基、羟基、磺酸基和仲氨基组成的组中选出的取代基或取代基的一部分，或代表包含仲氨基并可包含氮的芳香基团；通式(III)中的 R4 代表如下通式(III-1)所代表的芳香族氨基酸残基； X 代表-CHY-(CH3)2Z； Y 和 Z 分别为-H 或-OH 或共同形成单键：(III-1) 其中 R5 代表羟基，可有可无；n 代表 0 或 1 的整数。
• Chloroperoxidase-catalyzed asymmetric oxidations: substrate specificity and mechanistic study.
  作者：Aleksey Zaks、David R. Dodds

  DOI：10.1021/ja00147a001

  日期：1995.10

  The substrate specificity of chloroperoxidase from Caldaromyces fumago in a number of halide-independent reactions was investigated and the ability of this enzyme to perform benzylic hydroxylations with high enantioselectivity is revealed. The substrate repertoire of chloroperoxidase is expanded and the enantioselectivity data for synthetically useful epoxidations are reported. The enzyme epoxidizes straight chain aliphatic and cyclic cis-olefins in a highly stereoselective manner favoring small unsubstituted substrates in which the double bond is not more than two carbon atoms from the terminal. The epoxidation of short-chain prochiral terminal dienes proceeds with high diastereoselectivity and moderate enantioselectivity, yielding monoepoxides exclusively. Unsubstituted straight-chain terminal olefins seven carbons or longer are epoxidized poorly. Aliphatic and aromatic alcohols are efficiently oxidized to aldehydes and acids. The utilization of radical probe substrate trans-2-phenyl-1-methylcyclopropane revealed that the mechanism of chloroperoxidase-catalyzed hydroxylation is incompatible with the existence of a discrete radical intermediate and most likely proceeds via transfer of the oxygen atom from the high valent iron oxo intermediate directly to the substrate.
• Silanes in organic synthesis. 9. Enesilylation as a method for 1,2-carbonyl migration within ketones and for conversion to 1,2-transposed allylic alcohols
  作者：William E. Fristad、Thomas R. Bailey、Leo A. Paquette

  DOI：10.1021/jo01303a021

  日期：1980.7
• FRISTAD W. E.; BAILEY T. R.; PAQUETTE L. A., J. ORG. CHEM., 1980, 45, NO 15, 3028-3037
  作者：FRISTAD W. E.、 BAILEY T. R.、 PAQUETTE L. A.

  DOI：——

  日期：——