1,5-bis(4-aminophenyl)penta-1,4-dien-3-one | 1228557-64-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 1,5-bis(4-aminophenyl)penta-1,4-dien-3-one
• 英文别名: (1E,4E)-1,5-bis(4-aminophenyl)penta-1,4-dien-3-one
• CAS: 1228557-64-9
• 化学式: C₁₇H₁₆N₂O
• 分子量: 264.327
• InChiKey: XDWLQGNNVSVQQQ-YDWXAUTNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (1E,4E)-1,5-bis(4'-nitrophenyl)penta-1,4-dien-3-one 在 铁粉 、 氯化铵 作用下， 以 乙醇 、 水 为溶剂， 反应 1.0h， 生成 1,5-bis(4-aminophenyl)penta-1,4-dien-3-one
  参考文献：
  名称：

  Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation

  摘要：

  In a continuing study of hybrid compounds containing the alpha-bromoacryloyl moiety as potential anticancer drugs, we synthesized a novel series of hybrids 4a-h, in which this moiety was linked to a 1,5-diaryl-1,4-pentadien-3-one system. Many of the conjugates prepared (4b, 4c, 4e and 4g) demonstrated pronounced, submicromolar antiproliferative activity against four cancer cell lines. Moreover, compound 4b induced apoptosis through the mitochondrial pathway and activated caspase-3 in a concentration-dependent manner. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.03.075

文献信息

• Stable cationically crosslinkable/polymerizable dental composition with a high filler content
  申请人：Frances Jean-Marc

  公开号：US20080287562A1

  公开（公告）日：2008-11-20

  Stable and substantially filled cationic dental compositions are described which include: (1) at least one cationically reactive compound (A); (2) at least one dental filler (B); (3) optionally, at least one dispersant (C) composed of at least one organic polymer or copolymer; (4) at least one cationic photoinitiator (D); and (5) optionally, at least one photosensitizer (E). The dental filler (B) is treated with at least one organosilicon coupling agent (F), and at least one compound (G). The organosilicon coupling agent (F) has at least one reactive function (rfA) directly linked to a silicon atom forming after activation of a chemical bond with the dental filler, and at least one reactive function (rfB) not directly linked to a silicon atom, forming after activation, a chemical bond with a reactive function (rfC) of the compound (G).

  本文介绍了一种稳定且填充充足的阳离子牙科组合物，其中包括：（1）至少一种阳离子反应化合物（A）；（2）至少一种牙科填充物（B）；（3）可选地，至少一种由至少一种有机聚合物或共聚物组成的分散剂（C）；（4）至少一种阳离子光引发剂（D）；以及（5）可选地，至少一种光敏剂（E）。牙科填充物（B）经过至少一种有机硅偶联剂（F）处理，以及至少一种化合物（G）。有机硅偶联剂（F）具有至少一个反应功能（rfA），直接连接到形成化学键的硅原子上，与牙科填充物发生作用；以及至少一个反应功能（rfB），在激活后不直接连接到硅原子，与化合物（G）的反应功能（rfC）形成化学键。
• ALIGNING AGENT FOR LIQUID CRYSTAL
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP0980016A1

  公开（公告）日：2000-02-16

  The present invention relates to a treating agent for liquid crystal alignment, which is an agent for liquid crystal alignment to be used for a method in which polarized ultraviolet rays or electron rays are irradiated on a polymer thin film formed on a substrate in a predetermined direction relative to the substrate plane, and said substrate is used for aligning liquid crystal without rubbing treatment, wherein said agent for liquid crystal alignment contains a polymer compound having photochemically reactive groups in the polymer main chain and a glass transition temperature of at least 200°C.

  本发明涉及一种用于液晶配向的处理剂，它是一种用于液晶配向的处理剂，在该方法中，偏振紫外线或电子射线按相对于基底平面的预定方向照射在基底上形成的聚合物薄膜上，所述基底用于配向液晶而无需摩擦处理，其中所述液晶配向剂含有一种聚合物化合物，该聚合物化合物在聚合物主链中具有光化学反应基团，玻璃化温度至少为 200°C。
• Photoresist composition
  申请人：JAPAN SYNTHETIC RUBBER CO., LTD.

  公开号：EP0068808B1

  公开（公告）日：1985-06-05
• COMPOSITION DENTAIRE RETICULABLE/POLYMERISABLE PAR VOIE CATIONIQUE STABLE ET A HAUTE TENEUR EN CHARGE
  申请人：Bluestar Silicones France

  公开号：EP1745083B1

  公开（公告）日：2009-12-16
• DENTAL COMPOSITIONS CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS
  申请人：FRANCES Jean-Marc

  公开号：US20110189632A1

  公开（公告）日：2011-08-04

  Improvedly storage stable dental compositions useful for the preparation of dental prostheses and for dental restoration containing a uniquely pretreated dental filler material.