8-甲基-喹啉-5-磺酸 | 26866-33-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 8-甲基-喹啉-5-磺酸
• 中文别名: 8-甲基喹啉-5-磺酸
• 英文名称: 8-methyl-quinoline-5-sulfonic acid
• 英文别名: 8-Methyl-chinolin-5-sulfonsaeure；8-Methylquinoline-5-sulfonic acid
• CAS: 26866-33-1
• 化学式: C₁₀H₉NO₃S
• 分子量: 223.252
• InChiKey: JMXICTCPEGFCEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  8-甲基-喹啉-5-磺酸 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Herzfeld, Chemische Berichte, 1884, vol. 17, p. 1551

  摘要：

  DOI：
• 作为产物：
  描述：

  8-甲基喹啉 在 硫酸 作用下， 生成 8-甲基-喹啉-5-磺酸
  参考文献：
  名称：

  Herzfeld, Chemische Berichte, 1884, vol. 17, p. 905,1552

  摘要：

  DOI：

文献信息

• SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0525203A1

  公开（公告）日：1993-02-03

  A substituted sulfonamide derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, both of which act on a bronchial smooth muscle of a mammal and are effective as an active ingredient of a pharmaceutical composition for preventing and treating respiratory organ diseases such as asthma. In formula (I) A represents hydrogen or alkyl; G represents methylene or alkylene; Q1 represents ethylene; Q2 represents ethylene or trimethylene; E represents alkyl or a group of formula (II-a) or (II-b): -G-J-Z (II-a), -G-Z (II- b) wherein G is as defined above, J represents oxygen, sulfur or nitrogen, and Z represents alkyl, alkoxy, aryl, or heterocycle; and X represents quinoline, isoquinoline, benzothiazole or quinazolin-4-one.

  一种由通式(I)代表的取代磺酰胺衍生物或其药学上可接受的盐，二者均作用于哺乳动物的支气管平滑肌，作为预防和治疗呼吸器官疾病如哮喘的药物组合物的有效成分。在式(I)中，A代表氢或烷基；G代表亚甲基或亚烷基；Q1代表乙烯；Q2代表乙烯或三亚甲基；E代表烷基或式(II-a)或(II-b)的基团：-G-J-Z（II-a），-G-Z（II- b） 其中 G 如上定义，J 代表氧、硫或氮，Z 代表烷基、烷氧基、芳基或杂环；X 代表喹啉、异喹啉、苯并噻唑或喹唑啉-4-酮。
• PHTHALOCYANINE COMPOUND
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2206749B1

  公开（公告）日：2012-11-21
• Preparation of Substituted Quinolinyl and Isoquinolinyl Sulfonyl Chlorides for the Synthesis of Novel Sulfonamides
  作者：Lai, Justine Y. Q.、Ferguson, Yvonne、Jones, Mark

  DOI：10.1081/scc-120024002

  日期：2003.9

  Novel sulfonyl chlorides of quinolines and isoquinolines have successfully been prepared. This enabled the preparation of the corresponding sulfonamides via reaction with an amine using the "resin-capture and release" methodology.
• Herzfeld, Chemische Berichte, 1884, vol. 17, p. 903
  作者：Herzfeld

  DOI：——

  日期：——
• COLORANT COMPOUND AND INK INCLUDING THE COLORANT COMPOUND
  申请人：Tanaka Masatake

  公开号：US20100089284A1

  公开（公告）日：2010-04-15

  The invention provides a colorant compound represented by the following general formula (1): wherein R 1 and R 2 represent independently from each other a species selected from at least one of a hydrogen atom, an alkyl group, and an aralkyl group. R 3 represents a species selected from at least one of a hydrogen atom, a cyano group, and —COR 5 , where R 5 is any of a hydroxyl group, an alkoxy group, and an amino group. R 4 represents a species selected from at least one of a hydrogen atom, an alkyl group, an aryl group, and an aralkyl group. Cy represents an aryl group. Optionally, at least one anionic group may be present in the general formula (1).