| 937248-22-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 937248-22-1
• 化学式: C₁₆H₃₀O₆Si
• 分子量: 346.496
• InChiKey: UPXRQEVTZURTJG-XJFOESAGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.82
• 重原子数：
  23.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  63.22
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  、 乙酸酐 在 perchloric acid immobilized on silica gel 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以89%的产率得到1,3,5-tri-O-acetyl-2-O-(2-acetoxyisopropyl)-β-D-xylofuranoside
  参考文献：
  名称：

  An atom-efficient and powerful method for direct esterification of silyl ethers catalyzed by HClO4–SiO2

  摘要：

  An efficient and convenient procedure for direct esterification of alkyl and aryl silyl ethers with Ac2O and a catalyst system of perchloric acid immobilized on a silica gel (HClO4 SiO2) has been developed. The silyl protecting groups are directly replaced by acetyls and the protecting groups themselves are transformed into acetates as the sole byproducts, which can be readily recovered and converted back to silylchlorides, the original protecting agents, thus minimizing wastes. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.12.028
• 作为产物：
  描述：

  乙酸酐 、 1,2-O-isopropylidene-5-O-(tert-butyl)dimethylsilyl-α-D-xylofuranoside 在 O-(3-sulfopropyl)-functionalized nano γ-Al₂O₃ 作用下， 以 neat (no solvent) 为溶剂， 反应 0.5h， 以89%的产率得到
  参考文献：
  名称：

  Sulfonic acid functionalized nano γ-Al2O3 catalyzed per-O-acetylated of carbohydrates

  摘要：

  A simple and clean synthesis of per-O-acetylation carbohydrate derivatives has been accomplished by treatment of sugars with a stoichiometric quantity of acetic anhydride under solvent-free conditions in the presence of sulfonic acid functionalized nano gamma-Al2O3 as an efficient and environmentally benign catalyst. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2012.10.014