4-oxo-hexanoyl chloride | 98140-10-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-oxo-hexanoyl chloride
• 英文别名: 4-Oxo-hexanoylchlorid；4-oxohexanoyl chloride
• CAS: 98140-10-4
• 化学式: C₆H₉ClO₂
• 分子量: 148.589
• InChiKey: CXUVSBMLACDZFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-oxo-hexanoyl chloride 、 乙醇 在 sodium carbonate 作用下， 生成 5-ethoxy-5-ethyl-dihydro-furan-2-one
  参考文献：
  名称：

  Reactions of Succinyl Dichloride with Organometallic Reagents¹

  摘要：

  DOI：

  10.1021/jo01105a022
• 作为产物：
  描述：

  3-戊酮 、 草酰氯 生成 4-oxo-hexanoyl chloride
  参考文献：
  名称：

  Bashir-Hashemi A., Hardee J. R., Gelber Nathan, Qi Lida, Axenrod Theodore, J. Org. Chem, 59 (1994) N 8, S 2132-2134

  摘要：

  DOI：

文献信息

• Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as
  申请人：Schering A.G.

  公开号：US04906634A1

  公开（公告）日：1990-03-06

  Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents, especially as antiarrhythmic agents are described. Pharmaceutical formulations containing such compounds are also discussed.

  描述了新型N-[4-(氨基取代)苯基]甲磺酰胺类化合物及其作为心血管药物的用途，特别是作为抗心律失常药物的用途。还讨论了含有这类化合物的药物配方。
• PLANT GROWTH REGULATING COMPOUNDS
  申请人：Jung Pierre Joseph Marcel

  公开号：US20140371073A1

  公开（公告）日：2014-12-18

  The present invention relates to novel non-steroidal brassinosteroid mimetic derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants and/or promoting the germination of seeds.

  本发明涉及新型非甾体类油菜素类似物衍生物，以及制备它们的过程和中间体，包括它们的植物生长调节剂组合物和使用它们控制植物生长和/或促进种子萌发的方法。
• Novel-N-(4-(Aminosubstituted)phenyl) methanesulfonamides and their use as cardiovascular agents
  申请人：SCHERING AKTIENGESELLSCHAFT

  公开号：EP0332570A2

  公开（公告）日：1989-09-13

  Novel N-[4-aminosubstituted)phenyl]methane­sulfonamides and their use as cardiovascular agents, especially as antiarrhythmic agents are described. Pharmaceutical formulations containing such compounds are also discussed.

  介绍了新型 N-[4-氨基取代)苯基]甲磺酰胺类化合物及其作为心血管药物，特别是作为抗心律失常药物的用途。还讨论了含有此类化合物的药物制剂。
• Regioselectivity in Photochemical Chlorocarbonylation of Carbonyl Compounds
  作者：A. Bashir-Hashemi、J. R. Hardee、Nathan Gelber、Lida Qi、Theodore Axenrod

  DOI：10.1021/jo00087a033

  日期：1994.4

  Photochemical chlorocarbonylation of a series of cyclic and acyclic carbonyl compounds shows remarkable regioselectivity and gives beta- or gamma-substituted products in reasonable yields. Irradiation of cyclopentanone in oxalyl chloride followed by esterification with methanol gave methyl 3-oxocyclopentanecarboxylate (4). Similarly, photochemical chlorocarbonylation of cyclobutanone yielded methyl 3-oxocyclobutanecarboxylate (6). Application of the chlorocarbonylation reaction to 3-pentanone gave methyl 4-oxohexanoate (8) and dimethyl 4-oxopimelate (9). When a mixture of 3-methylbutanoic acid and oxalyl chloride was irradiated, dimethyl 3-methylglutarate (11) was obtained after methanolysis. A kinetically-controlled mechanism for the photochemical process was deduced.
• Kafka, Stanislav; Kytner, Jan; Silhankova, Alexandra, Collection of Czechoslovak Chemical Communications, 1987, vol. 52, # 8, p. 2035 - 2046
  作者：Kafka, Stanislav、Kytner, Jan、Silhankova, Alexandra、Ferles, Miloslav

  DOI：——

  日期：——