1,1,3,3-tetrabromo-4-methyl-pentan-2-one | 1578-20-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1,3,3-tetrabromo-4-methyl-pentan-2-one
• 英文别名: 1,1,3,3-Tetrabromo-4-methylpentan-2-one
• CAS: 1578-20-7
• 化学式: C₆H₈Br₄O
• 分子量: 415.745
• InChiKey: APHDNZLLUCBKNZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,1,3,3-tetrabromo-4-methyl-pentan-2-one 在 sodium tetrahydroborate 、 diethylzinc 、 铜 、 氯化铵 、 锌 作用下， 以 甲醇 为溶剂， 反应 81.0h， 生成 4α-isopropyl-1-methyl-8-oxabicyclo[3.2.1]oct-6-en-3-ol
  参考文献：
  名称：

  New 8-Oxabicyclo[3.2.1]oct-6-en-3-one Derivatives with Plant Growth Regulatory Activity

  摘要：

  Several 8-oxabicyclo[3.2.1]oct-6-en-3-one derivatives have been prepared via the [3 + 4] cycloaddition between the oxyallyl carbocation generated from polybromoketones and alkylfurans. The selective effects of these compounds on the radicle growth of a monocotyledon [sorghum (Sorghum bicolor L.)] and a dicotyledon [cucumber (Cucumis sativus L.)] were evaluated. All of the test compounds, at the concentration of 100 mu g mL(-1), stimulated cucumber root growth (5-30%), but they inhibited sorghum root growth (23-56%). None of the compounds had any effect on the percent of germination of the species tested.

  DOI：

  10.1021/jf970413s
• 作为产物：
  描述：

  4-甲基-2-戊酮 在 溴 、 三溴化磷 作用下， 以92.8%的产率得到1,1,3,3-tetrabromo-4-methyl-pentan-2-one
  参考文献：
  名称：

  Barbosa, Luiz Claudio de Almeido; Demuner, Antonio J.; Mann, John, Journal of the Chemical Society. Perkin transactions I, 1993, # 5, p. 585 - 588

  摘要：

  DOI：

文献信息

• Cycloaddition reactions of polysubstituted furans with oxyallyl carbocations
  作者：John Mann、Helen J. Holland (née Overton)、Terrence Lewis

  DOI：10.1016/s0040-4020(01)81660-4

  日期：——

  New and improved routes to polysubstituted furans are described, together with a survey of their reactivity in cycloaddition reactions with oxyallyl carbocations, producing polysubstituted 8-oxabicyclo[3.2.1]oct-6-en-3-ones.

  描述了制备多取代的呋喃的新的和改进的途径，以及对它们在与氧烯丙基碳环的环加成反应中反应性的调查，该反应产生了多取代的8-氧杂双环[3.2.1] oct-6-en-3-one。
• Mann, John; Barbosa, Luiz-Claudio de Almeida, Journal of the Chemical Society. Perkin transactions I, 1992, # 7, p. 787 - 790
  作者：Mann, John、Barbosa, Luiz-Claudio de Almeida

  DOI：——

  日期：——
• MANN, JOHN;HOLLAND, HELEN J.;LEWIS, TERRENCE, TETRAHEDRON, 43,(1987) N 11, 2533-2542
  作者：MANN, JOHN、HOLLAND, HELEN J.、LEWIS, TERRENCE

  DOI：——

  日期：——
• New 8-Oxabicyclo[3.2.1]oct-6-en-3-one Derivatives with Plant Growth Regulatory Activity
  作者：Antonio J. Demuner、Luiz C. A. Barbosa、Dorila P. Veloso

  DOI：10.1021/jf970413s

  日期：1998.3.1

  Several 8-oxabicyclo[3.2.1]oct-6-en-3-one derivatives have been prepared via the [3 + 4] cycloaddition between the oxyallyl carbocation generated from polybromoketones and alkylfurans. The selective effects of these compounds on the radicle growth of a monocotyledon [sorghum (Sorghum bicolor L.)] and a dicotyledon [cucumber (Cucumis sativus L.)] were evaluated. All of the test compounds, at the concentration of 100 mu g mL(-1), stimulated cucumber root growth (5-30%), but they inhibited sorghum root growth (23-56%). None of the compounds had any effect on the percent of germination of the species tested.
• Barbosa, Luiz Claudio de Almeido; Demuner, Antonio J.; Mann, John, Journal of the Chemical Society. Perkin transactions I, 1993, # 5, p. 585 - 588
  作者：Barbosa, Luiz Claudio de Almeido、Demuner, Antonio J.、Mann, John、Veloso, Dorila P.

  DOI：——

  日期：——