1-(2-Chlorophenyl)-5-methyl-3-(trifluoromethyl)pyrazole | 915378-29-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2-Chlorophenyl)-5-methyl-3-(trifluoromethyl)pyrazole
• CAS: 915378-29-9
• 化学式: C₁₁H₈ClF₃N₂
• 分子量: 260.646
• InChiKey: BUESTMXBZVAJKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(2-Chlorophenyl)-5-methyl-3-(trifluoromethyl)pyrazole 在 potassium permanganate 、 十六烷基三甲基氯化铵 作用下， 生成 1-(2-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
  参考文献：
  名称：

  Insecticidal anthranilic diamides: A new class of potent ryanodine receptor activators

  摘要：

  A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.08.034
• 作为产物：
  描述：

  三氟乙酰丙酮 、 (2-氯苯基)-肼 在 sodium acetate 、 溶剂黄146 作用下， 生成 、 1-(2-Chlorophenyl)-5-methyl-3-(trifluoromethyl)pyrazole
  参考文献：
  名称：

  Insecticidal anthranilic diamides: A new class of potent ryanodine receptor activators

  摘要：

  A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.08.034

文献信息

• Hydrazide Compound and Pesticidal Use of the Same
  申请人：Ikegami Hiroshi

  公开号：US20090181956A1

  公开（公告）日：2009-07-16

  A hydrazide compound represented by the formula (1): has excellent pesticidal activity.

  一种由式（1）表示的腙酰肼类化合物具有出色的杀虫活性。
• BICYCLIC ANTHRANILAMIDE DERIVATIVES USEFUL AS INSECTICIDES
  申请人：Syngenta Participations AG

  公开号：EP1737844B1

  公开（公告）日：2010-08-25
• EP2121621B1
  申请人：——

  公开号：EP2121621B1

  公开（公告）日：2014-05-07
• Novel Insecticides
  申请人：Hughes John David

  公开号：US20070281930A1

  公开（公告）日：2007-12-06

  Compounds of the formula in which Z 1 is an oxygen atom; or a sulfur atom; Z 2 is an oxygen atom; or a sulfur atom; R 1 is an aryl or heteroaryl group, which is unsubstituted or substituted; R 2 is hydrogen; or an organic substituent; R 3 is hydrogen; or an organic substituent; R 4 is hydrogen; or an organic substituent; or R 3 and R 4 , taken together, form, together with the nitrogen atom, to which they are attached, a ring, which is unsubstituted or substituted; R 5 is hydrogen; or an unsubstituted or substituted alkyl group; or forms, taken together with R 8 or with a monovalent substituent attached to that atom of R 6 , via which atom R 6 is directly connected with the carbon atom, shown in the formula I, which carries R 5 , one additional bond; R 6 and R 7 , taken together, form, together with the two carbon atoms, shown in the formula I, to which atoms they are attached, a bicyclic ring system, which ring system is carbocyclic or heterocyclic, which ring system is substituted, in the manner shown in the formula I, by the four substituents —N(R 2 )—C(=Z 1 )—R 1 , —C(=Z 2 )-N(R 3 )—R 4 , R 5 and R 8 , and which ring system is optionally further substituted; and R 8 is hydrogen; or an unsubstituted or substituted alkyl group; or forms, taken together with R 5 or with a monovalent substituent attached to that atom of R 7 , via which atom R 7 is directly connected with the carbon atom, shown in the formula I, which carries R 8 , one additional bond, and, where appropriate, tautomers thereof, in each case in free form or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
• US7812170B2
  申请人：——

  公开号：US7812170B2

  公开（公告）日：2010-10-12