11-Bromoundecane-1,10-diol | 142999-79-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: 11-Bromoundecane-1,10-diol
• CAS: 142999-79-9
• 化学式: C₁₁H₂₃BrO₂
• 分子量: 267.206
• InChiKey: BGSKAUNKFNLKSY-UHFFFAOYSA-N

物化性质

• 沸点：
  350.3±12.0 °C(Predicted)
• 密度：
  1?+-.0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  10,11-epoxyundecan-1-ol 在 四丁基溴化铵 、 三氯化锑 、 sodium thiosulfate 作用下， 以 四氢呋喃 为溶剂， 反应 65.0h， 以82%的产率得到11-Bromoundecane-1,10-diol
  参考文献：
  名称：

  Reductive Ring‐Opening Reaction of 2,3‐Epoxy‐1,4‐butanediones with SbCl₃‐Bu₄NI in the Presence of Na₂S₂O₃·5H₂O

  摘要：

  1,4-Disubstituted 2,3 -epoxy-1,4-butanediones were converted to 1,4-disubstituted 2-hydroxy-1,4-butanediones with SbCl3-Bu4NI in the presence of Na(2)S(2)O(3)center dot 5H(2)O. The ring opening of terminal epoxides can also be accomplished to afford the corresponding haloalcohol with SbCl3 and tetrabutylammonium halides, Bu4NX (X = Cl, Br, I) under the same reaction conditions.

  DOI：

  10.1080/00397910500180121

文献信息

• An Easy Procedure for the Highly Regioselective Conversion of Epoxides to Halohydrins
  作者：Bonini、Giuliano、Righi、Rossi

  DOI：10.1080/00397919208021317

  日期：1992.7

  Several epoxides and epoxy alcohols have been opened to the corresponding halohydrins by lithium halides with Amberlyst in CH3CN at room temperature : the reaction proceeds in quantitative yields with high degree of regioselectivity.
• Reductive Ring‐Opening Reaction of 2,3‐Epoxy‐1,4‐butanediones with SbCl₃‐Bu₄NI in the Presence of Na₂S₂O₃·5H₂O
  作者：Shinsei Sayama

  DOI：10.1080/00397910500180121

  日期：2005.8.1

  1,4-Disubstituted 2,3 -epoxy-1,4-butanediones were converted to 1,4-disubstituted 2-hydroxy-1,4-butanediones with SbCl3-Bu4NI in the presence of Na(2)S(2)O(3)center dot 5H(2)O. The ring opening of terminal epoxides can also be accomplished to afford the corresponding haloalcohol with SbCl3 and tetrabutylammonium halides, Bu4NX (X = Cl, Br, I) under the same reaction conditions.