7-chloro-2-selenoquinoline-3-formaldehyde | 1013317-28-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-chloro-2-selenoquinoline-3-formaldehyde
• CAS: 1013317-28-6
• 化学式: C₁₀H₆ClNOSe
• 分子量: 270.577
• InChiKey: TUJUOQSDTCGDMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.23
• 重原子数：
  14.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.96
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  7-chloro-2-selenoquinoline-3-formaldehyde 在 一水合肼 作用下， 生成 7-chloro-3-(hydrazineylidenemethyl)quinoline-2-selenol
  参考文献：
  名称：

  Synthesis of Quinoline-Based Thieno-Seleno-Phenylquinazolinones

  摘要：

  The synthesis of quinoline-substituted phenylquinazolinones containing sulfur and selenium is described. These molecules were isolated from a series of reactions of 2-phenyl-4H-3,1-benzoxazin-4-one with 2-chloro, 2-thieno, and 2-selenoquinoline-3-carbaldehyde hydrazones. The structure of the isolated compounds has been elucidated on the basis of IR, 1H NMR, mass spectral, and elemental analysis data.

  DOI：

  10.1080/10426500802176945
• 作为产物：
  描述：

  2,7-二氯喹啉-3-羧醛 在 sodium tetrahydroborate 、 sodium hydrogen selenide 作用下， 以 乙醇 、 水 为溶剂， 以73%的产率得到7-chloro-2-selenoquinoline-3-formaldehyde
  参考文献：
  名称：

  Synthesis of New Seleno-Substituted Quinolines

  摘要：

  The design and synthesis of organoselenium compounds with biological activity currently constitute engaging fundamental problems in applied chemistry in both pharmaceutical and academic laboratories. In this communication we would like to report the synthesis of new organo selenium compounds under mild reaction conditions. The newly synthesized compounds were characterized by elemental analysis, IR, H-1 NMR, and mass spectral studies.

  DOI：

  10.1080/10426500601088978