2-prop-2-ynyl-2-(9-trimethylsilyl-nona-2,8-diynyl)-[1,3] dioxane | 213040-24-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-prop-2-ynyl-2-(9-trimethylsilyl-nona-2,8-diynyl)-[1,3] dioxane
• CAS: 213040-24-5
• 化学式: C₂₁H₃₂O₂Si
• 分子量: 344.569
• InChiKey: BNGMQDANHHGKMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.61
• 重原子数：
  24.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2-prop-2-ynyl-2-(9-trimethylsilyl-nona-2,8-diynyl)-[1,3] dioxane 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 2.0h， 生成 2,2-dimethyl-5-(4-methyl-2-phenyl-penta-2,3-dienyl)-5-nona-2,8-diynyl-[1,3]dioxane
  参考文献：
  名称：

  Synthesis of variously substituted allenediynes and their cobalt (I)-mediated [2+2+2] cycloaddition reactions

  摘要：

  Syntheses of variously substituted allenediynes where the allene moiety is at the terminal or internal position are described. Their cobalt(I)-mediated [2+2+2] cycloaddition reactions led to the corresponding eta(4)-complexed tricyclic compounds; the regioselectivity of these cyclizations depending on the substitution and the position of the allene is discussed. (C) 1998 Elsevier Science Ltd. Ali rights reserved.

  DOI：

  10.1016/s0040-4020(98)00567-5
• 作为产物：
  描述：

  methyl methyl-(9-trimethylsilyl-nona-2,8-diyne)-(2-propynyl)-propane-dioate 在 lithium aluminium tetrahydride 、 对甲苯磺酸 作用下， 以 乙醚 为溶剂， 反应 4.0h， 生成 2-prop-2-ynyl-2-(9-trimethylsilyl-nona-2,8-diynyl)-[1,3] dioxane
  参考文献：
  名称：

  Synthesis of variously substituted allenediynes and their cobalt (I)-mediated [2+2+2] cycloaddition reactions

  摘要：

  Syntheses of variously substituted allenediynes where the allene moiety is at the terminal or internal position are described. Their cobalt(I)-mediated [2+2+2] cycloaddition reactions led to the corresponding eta(4)-complexed tricyclic compounds; the regioselectivity of these cyclizations depending on the substitution and the position of the allene is discussed. (C) 1998 Elsevier Science Ltd. Ali rights reserved.

  DOI：

  10.1016/s0040-4020(98)00567-5