7-甲氧基甲基-12-甲基苯并[a]蒽 | 13345-60-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 中文名称: 7-甲氧基甲基-12-甲基苯并[a]蒽
• 英文名称: methyl-(12-methyl-benz[a]anthracen-7-ylmethyl)-ether
• 英文别名: Methyl-(12-methyl-benz[a]anthracen-7-ylmethyl)-aether；12-Methyl-7-methoxymethyl-benz[a]anthracen；7-Methoxymethyl-12-methyl-benzanthracen；Benz(a)anthracene, 7-(methoxymethyl)-12-methyl-；7-(methoxymethyl)-12-methylbenzo[a]anthracene
• CAS: 13345-60-3
• 化学式: C₂₁H₁₈O
• 分子量: 286.373
• InChiKey: ZPGGXMUXSHFETD-UHFFFAOYSA-N

物化性质

• 熔点：
  120-121 °C
• 沸点：
  388.73°C (rough estimate)
• 密度：
  1.0402 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909199090

SDS

反应信息

• 作为反应物：
  描述：

  7-甲氧基甲基-12-甲基苯并[a]蒽 在 氢溴酸 作用下， 生成 苯并(a)蒽,7-溴甲基-12-甲基.
  参考文献：
  名称：

  混合双功能。4.多环芳烃的烷基化衍生物的抗肿瘤活性作为结构和载体的函数。

  摘要：

  DOI：

  10.1021/jm00271a018
• 作为产物：
  描述：

  苯并蒽-7,12-二酮 在 甲醇 、 乙醚 、 苯 作用下， 生成 7-甲氧基甲基-12-甲基苯并[a]蒽
  参考文献：
  名称：

  Synthesis of 9,10-Dimethyl-1,2-benzanthracene and of a Thiophene Isolog

  摘要：

  DOI：

  10.1021/ja01868a055

文献信息

• Pheromone content of azinphosmethyl-susceptible and -resistant obliquebanded leafrollers (Lepidoptera: Tortricidae) as a function of time of day and female age
  作者：Ashraf M. El-Sayed、R.M. Trimble

  DOI：10.4039/ent134331-3

  日期：2002.6

  The effect of time of day and age on the amounts and ratios of four pheromone compounds [(Z)-11-tetradecenyl acetate (Z11-14:Ac), (E)-11-tetradecenyl acetate (E11-14:Ac), (Z)-11-tetradecenol (Z11-14:OH), and (Z)-11-tetradecenal (Z11-14:Al)] was compared in azinphosmethyl-susceptible (susceptible) and -resistant (resistant) female obliquebanded leafrollers, Choristoneura rosaceana (Harris). The amounts of all four pheromone compounds varied during the hour before and five hours after the onset of scotophase. The glands of resistant females contained approximately one half the amount of Z11-14:Ac and Z11-14:OH as the glands of susceptible females during the second and third hours of scotophase, and between 50 and 70% as much Z11-14:Al as the glands of susceptible females during the hour before and second to fourth hours of scotophase. The glands of susceptible and resistant females contained similar amounts of E11-14:Ac. The relative amounts of each of the four pheromone compounds were affected by time of day but not by resistance status. There was a negative linear relationship between the amounts of each of the four compounds and female age in both types of females. The amounts of Z11-14:Ac and E11-14:Ac declined at similar rates with age in susceptible and resistant females; the amounts of Z11-14:OH and Z11-14:Al declined more rapidly with age in susceptible than in resistant females. The relative amounts of the four compounds were not affected by female age. Temporal variation in the relative amounts of pheromone in susceptible and resistant C. rosaceana may be associated with similar variation in the emission of pheromone and corresponding temporal variation in the relative attractiveness of the two types of females.

  摘要 比较了一天中的时间和年龄对四种信息素化合物[(Z)-11-十四烯基乙酸酯（Z11-14:Ac）、(E)-11-十四烯基乙酸酯（E11-14:Ac）、(Z)-11-十四烯醇（Z11-14：OH）和 (Z)-11-十四烯醛（Z11-14:Al）]进行了比较。所有四种信息素化合物的含量在光照开始前一小时和光照开始后五小时内各不相同。在光斑期的第二和第三小时，抗性雌虫腺体中 Z11-14:Ac 和 Z11-14:OH 的含量约为易感雌虫腺体的一半；在光斑期开始前一小时和第二至第四小时，抗性雌虫腺体中 Z11-14:Al 的含量约为易感雌虫腺体的 50% 至 70%。易感雌虫和抗性雌虫腺体中的 E11-14:Ac 含量相似。四种信息素化合物的相对含量受一天中时间的影响，但不受抗性状态的影响。两种雌虫的四种化合物的含量与雌虫的年龄呈负线性关系。在易感雌性和抗性雌性中，Z11-14:Ac和E11-14:Ac的含量随年龄下降的速度相似；在易感雌性中，Z11-14:OH和Z11-14:Al的含量随年龄下降的速度比抗性雌性快。四种化合物的相对含量不受雌性年龄的影响。易感性和抗性蔷薇雌虫信息素相对含量的时间变化可能与信息素释放量的相似变化以及两种雌虫相对吸引力的相应时间变化有关。
• 474. Substituted anthracene derivatives. Part III. Further examples of 1 : 5-anionotropic rearrangements
  作者：G. M. Badger、R. S. Pearce

  DOI：10.1039/jr9500002314

  日期：——
• Syntheses of Metabolites of 7,12-Dimethylbenz[<i>a</i>]anthracene. 4-Hydroxy-7,12-dimethylbenz[<i>a</i>]anthracene, 7-Hydroxymethyl-12-methylbenz[<i>a</i>]anthracene, Their Methyl Ethers, and Acetoxy Derivatives
  作者：James W. Flesher、Soekeni. Soedigdo、Donald R. Kelley

  DOI：10.1021/jm00317a040

  日期：1967.9
• Synthesis of 9,10-Dimethyl-1,2-benzanthracene and of a Thiophene Isolog
  作者：Reuben B. Sandin、Louis F. Fieser

  DOI：10.1021/ja01868a055

  日期：1940.11
• Mixed bifunctionality. 4. Antitumor activity of alkylating derivatives of polycyclic aromatic hydrocarbons as a function of structure and of vehicle
  作者：Richard M. Peck、Anna P. O'Connell

  DOI：10.1021/jm00271a018

  日期：1972.1