2-methyl-8-(2,3,4,5-tetramethyl-4H-cyclopenta[b]thiophen-6-yl)-1,2,3,4-tetrahydroquinoline | 1253693-15-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-methyl-8-(2,3,4,5-tetramethyl-4H-cyclopenta[b]thiophen-6-yl)-1,2,3,4-tetrahydroquinoline
• CAS: 1253693-15-0
• 化学式: C₂₁H₂₅NS
• 分子量: 323.502
• InChiKey: AVHIEYQXXNHNRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  40.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methyl-8-(2,3,4,5-tetramethyl-4H-cyclopenta[b]thiophen-6-yl)-1,2,3,4-tetrahydroquinoline 在 甲基锂 、 bis(dimethylamido)titanium(IV) dichloride 、 二氯二甲基硅烷 作用下， 以 乙醚 、 甲苯 为溶剂， 反应 75.0h， 以75%的产率得到2-methyl-3H-4,5-dimethyl-6-(2-methyl-2,3,4,5-tetrahydroquinolin-8-yl)-4H-cyclopentathiophene titanium dichloride
  参考文献：
  名称：

  GROUP 4 METAL COMPOUND CONTAINING THIOPHENE-FUSED CYCLOPENTADIENYL LIGAND DERIVED FROM TETRAQUINOLINE DERIVATIVE AND OLEFIN POLYMERIZATION USING THE SAME

  摘要：

  本发明涉及一种源自四氢喹啉衍生物的新型配体，以及使用该配体制备的过渡金属化合物，其中一个酰胺配体连接到邻菲啰啉配体以形成一个紧凑的环，并且连接到邻菲啰啉配体的一个五元环π-配体与一个杂环噻吩配体融合。与未与杂环噻吩配体融合的催化剂相比，本发明的过渡金属化合物在与辅助催化剂激活时具有更高的烯烃聚合催化活性，并提供具有更高分子量的聚合物。

  公开号：

  US20130203949A1
• 作为产物：
  描述：

  2,3-二甲基噻吩 在 正丁基锂 、 碳酸氢钠 作用下， 以 乙醚 、 正己烷 、 二氯甲烷 、 水 为溶剂， 反应 5.67h， 生成 2-methyl-8-(2,3,4,5-tetramethyl-4H-cyclopenta[b]thiophen-6-yl)-1,2,3,4-tetrahydroquinoline
  参考文献：
  名称：

  Preparation of half-metallocenes of thiophene-fused and tetrahydroquinoline-linked cyclopentadienyl ligands for ethylene/α-olefin copolymerization

  摘要：

  来源于四氢喹啉或四氢奎啉胺的锂氨基甲酸盐的定向邻位锂化反应实现了硫烯烷基和四氢喹啉连接的环戊二烯的单步合成 [2-R1-3-R2-4,5-二甲基-6-(2-R3-2,3,4,5-四氢喹啉-8-基)-4H-环戊[b]硫烯 (R1, R2, R3 = H 或甲基)]。从中可以制备钛(IV)和锆(IV)络合物。通过X射线晶体学确定了Me2Ti络合物（12，R1 = R2 = Me，R3 = H；14，R1 = R2 = R3 = Me）和Cl2Zr络合物（17，R1 = R2 = Me，R3 = H）的分子结构。Me2Ti络合物14和15（R1 = R3 = Me，R2 = H）在乙烯/1-辛烯共聚合中表现出优异的活性（62和54 × 10^6 g/molTi·h），即使在仅用少量MAO激活（Al/Ti = 1000）的情况下也如此。

  DOI：

  10.1039/c0dt00637h

文献信息

• GROUP 4 METAL COMPOUND OF THIOPHENE-FUSED CYCLOPENTADIENYL LIGAND TETRAHYDROQUINOLINE DERIVATIVE, AND OLEFIN POLYMERIZATION USING SAME
  申请人：Lotte Chemical Corporation

  公开号：EP2559695B1

  公开（公告）日：2017-06-14
• CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND PREPARATION METHOD FOR POLYOLEFIN USING THE SAME
  申请人：Lee Bun-Yeoul

  公开号：US20130211020A1

  公开（公告）日：2013-08-15

  The present invention relates to a catalyst composition comprising a novel transition metal compound and a preparation method for polyolefin using the same. The catalyst composition of the present invention has high catalytic activity for polymerization of olefin-based monomers and enables it to control the fine-structure characteristics of the polyolefin, such as molecular weight distribution, in a wide range, thereby easily providing a polyolefin with desired properties.
• SUPPORTED CATALYST FOR OLEFIN POLYMERIZATION AND PREPARATION METHOD FOR POLYOLEFIN USING THE SAME
  申请人：Lee Bun-Yeoul

  公开号：US20130211023A1

  公开（公告）日：2013-08-15

  The present invention relates to a supported catalyst for olefin polymerization to which a novel transition metal compound and a co-catalyst compound are bound, and a preparation method for polyolefin using the supported catalyst. The transition metal compound bound to the catalyst of the present invention provides high activity for olefin-based monomers in heterogeneous reaction as well as in homogeneous system. Particularly, a polyolefin with higher molecular weight can be prepared by using the supported catalyst containing the transition metal compound bound to a support, rather than using the novel transition metal compound in a non-supported status, or the conventional transition metal compound in a supported or non-supported status.
• METHOD FOR PREPARING OLEFIN-DIENE COPOLYMER USING TRANSITION METAL COMPOUND CONTAINING THIOPHENE-FUSED CYCLOPENTADIENYL LIGAND
  申请人：Lee Bun-Yeoul

  公开号：US20130211024A1

  公开（公告）日：2013-08-15

  The present invention relates to a preparation method for olefin-diene copolymer that comprises polymerizing at least one olefin-based monomer and at least one diene-based monomer in the presence of a catalyst comprising a novel transition metal compound. Using the novel transition metal compound as a catalyst, the preparation method for olefin-diene copolymer according to the present invention can not only acquire high catalytic activity for copolymerization of the olefin and diene monomers to achieve high process efficiency but allow it to easily control the fine-structure characteristics of the copolymer, thereby providing an olefin-diene copolymer having desired properties with ease.
• METHOD FOR PREPARING POLYPROPYLENE USING TRANSITION METAL COMPOUND CONTAINING THIOPHENE-FUSED CYCLOPENTADIENYL LIGAND
  申请人：Lee Bun-Yeoul

  公开号：US20130211021A1

  公开（公告）日：2013-08-15

  The present invention relates to a preparation method for polypropylene that comprises polymerizing a propylene monomer in the presence of a catalyst comprising a novel transition metal compound. Using the novel transition metal compound as a catalyst, the preparation method for polypropylene according to the present invention can not only acquire high catalytic activity for polymerization to achieve high efficiency of the process but allow it to easily control the fine-structure characteristics of the polymer, thereby providing polypropylene having desired properties with ease.