[(10Z)-5-but-3-ynylhexadeca-1,10-dien-6-yn-5-yl]oxy-triethylsilane | 208249-49-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(10Z)-5-but-3-ynylhexadeca-1,10-dien-6-yn-5-yl]oxy-triethylsilane
• CAS: 208249-49-4
• 化学式: C₂₆H₄₄OSi
• 分子量: 400.72
• InChiKey: NHKMOJMEMBMLMW-HNENSFHCSA-N

物化性质

• 沸点：
  456.454±45.00 °C(Press: 760.00 Torr)(predicted)
• 密度：
  0.879±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.05
• 重原子数：
  28
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [(10Z)-5-but-3-ynylhexadeca-1,10-dien-6-yn-5-yl]oxy-triethylsilane 在 Grubbs catalyst first generation 作用下， 以 苯 为溶剂， 反应 4.0h， 以84%的产率得到Triethyl(2,3,4,5,8,9-hexahydrocyclopenta[a]naphthalen-3a-yloxy)silane
  参考文献：
  名称：

  Ruthenium-Catalyzed Polycyclization Reactions

  摘要：

  The application of ruthenium alkylidenes such as 1 to the catalysis of polycyclization reactions is reported. Several acyclic precursors have been synthesized and reacted with 1. These precursors vary in topology and contain acetylenic and/or cycloolefinic metathesis relays. The cyclization reactions proceed in moderate to good yields to produce polycyclic polyenes when the precursors are subjected to catalytic amounts of 1. In general, precursors bearing n relay units generate polycycles containing (n + 1) rings.

  DOI：

  10.1021/jo972279g
• 作为产物：
  描述：

  (Z)-4-癸烯醛 在 正丁基锂 、 potassium tert-butylate 、 三乙胺 作用下， 以 四氢呋喃 为溶剂， 生成 [(10Z)-5-but-3-ynylhexadeca-1,10-dien-6-yn-5-yl]oxy-triethylsilane
  参考文献：
  名称：

  Ruthenium-Catalyzed Polycyclization Reactions

  摘要：

  The application of ruthenium alkylidenes such as 1 to the catalysis of polycyclization reactions is reported. Several acyclic precursors have been synthesized and reacted with 1. These precursors vary in topology and contain acetylenic and/or cycloolefinic metathesis relays. The cyclization reactions proceed in moderate to good yields to produce polycyclic polyenes when the precursors are subjected to catalytic amounts of 1. In general, precursors bearing n relay units generate polycycles containing (n + 1) rings.

  DOI：

  10.1021/jo972279g