2-丙基-3-二甲氨基丙烯醛 | 85907-41-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-丙基-3-二甲氨基丙烯醛
• 英文名称: 2-propyl-3-dimethylaminoacrolein
• 英文别名: 3-dimethylamino-2-propyl-acrylaldehyde；3ξ-Dimethylamino-2-propyl-acrylaldehyd；3-Dimethylamino-2-propyl-acrylaldehyd；3-Dimethylamino-2-n-propyl-acrolein；(2Z)-2-(dimethylaminomethylidene)pentanal
• CAS: 85907-41-1
• 化学式: C₈H₁₅NO
• 分子量: 141.213
• InChiKey: FCGSKXFVOYPISO-VURMDHGXSA-N

物化性质

• 沸点：
  305.6±15.0 °C(Predicted)
• 密度：
  0.890±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-丙基-3-二甲氨基丙烯醛 在 sodium hydroxide 作用下， 生成 propylmalonaldehyde
  参考文献：
  名称：

  Arnold; Sorm, Collection of Czechoslovak Chemical Communications, 1958, vol. 23, p. 452,455

  摘要：

  DOI：
• 作为产物：
  描述：

  N,N-二甲基甲酰胺 在 光气 、 1,2-二氯乙烷 作用下， 生成 2-丙基-3-二甲氨基丙烯醛
  参考文献：
  名称：

  Arnold; Sorm, Collection of Czechoslovak Chemical Communications, 1958, vol. 23, p. 452,455

  摘要：

  DOI：

文献信息

• PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS
  申请人：Wacker Dean A.

  公开号：US20090023702A1

  公开（公告）日：2009-01-22

  Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR 119 G protein-coupled receptor modulator therapy. These novel compounds have the structure Formula I or Formula IA.

  提供了一些新的化合物，它们是GPR119 G蛋白偶联受体调节剂。GPR119 G蛋白偶联受体调节剂在治疗、预防或减缓需要GPR 119 G蛋白偶联受体调节剂疗法的疾病方面非常有用。这些新的化合物具有结构式I或结构式IA。
• Bipyrimidinyl derivatives and liquid crystal compositions containing them
  申请人：Chisso Corporation

  公开号：EP0160790A2

  公开（公告）日：1985-11-13

  A novel bipyrimidinyl derivative which is superior in practical properties and useful as a high temperature liquid crystal component constituting a physically and chemically stable liquid crystal composition is provided, which bipyrimidinyl derivative is a 2, 5' -disubstituted- 5, 2' -bipyrimidinyl expressed by the formula represants represents a halogen atom of F, Cℓ or Br or cyano group or an alkyl group or an alkoxy group each having 1 to 10 carbon atoms and R represents an alkyl group or an alkoxy group each having 1 to 10 carbon atoms.

  本发明提供了一种新型双嘧啶基衍生物，该衍生物具有优异的实用性能，可用作高温液晶成分，构成物理和化学性质稳定的液晶组合物，该双嘧啶基衍生物是由式表示的 2, 5' -二取代- 5, 2' -双嘧啶基，式中代表 F、Cℓ 或 Br 的卤素原子或氰基或烷基或烷氧基，每个烷基或烷氧基具有 1 至 10 个碳原子，R 代表烷基或烷氧基，每个烷基或烷氧基具有 1 至 10 个碳原子。
• Determinants of Body Composition in Postmenopausal Women
  作者：J. M. Hagberg、J. M. Zmuda、S. D. McCole、K. S. Rodgers、K. R. Wilund、G. E. Moore

  DOI：10.1093/gerona/55.10.m607

  日期：2000.10.1

  Background. Little is known about the effects of different levels of long-term physical activity on total body and regional fat and whether hormone replacement therapy interacts with physical activity level to affect body composition in postmenopausal women.Methods. We determined the associations between different levels of habitual physical activity, hormone replacement therapy (HRT), and total and regional body composition in postmenopausal women. Twenty sedentary, 20 active nonathletic, and 23 endurance-trained women (approximately half on HRT) had total and regional body composition assessed by dual-energy x-ray absorptiometry. The athletes and active nonathletic women had been active for the same number of years and the same number of hours per week.Results, The athletes and sedentary women weighed the same, but the active nonathletic groups on and not on HRT weighed 3-12 kg more (p < .05). Athletes had less trunk, arm, leg, and total body fat than sedentary and active nonathletic women (p < .05). Women on HRT tended to have lower total body (p = .07), but not regional, fat values. Linear regression analyses indicated that (V) over dot O-2 max in ml/kg/min was the major independent determinant of total and regional; body fat accounting for 52% to 70% of their variances. Athletes had greater caloric and carbohydrate intake than their less active peers, but all groups had similar protein, fat, saturated fat, monounsaturated fat, and polyunsaturated fat intakes.Conclusions. Intense training, but not low- to moderate-intensity physical activity, is associated with markedly lower levels of total and regional body fat in postmenopausal women. HRT has less of an effect on body composition than intense exercise training in postmenopausal women.
• Synthesis and liquid crystal properties of substituted 1,4-bis(pyrimidin-2-yl)benzenes
  作者：M. A. Mikhaleva、T. A. Kizner、N. I. Chernova、M. V. Loseva、G. A. Kolesnichenko、A. Z. Rabinovich、A. E. Kuznetsova、V. P. Mamaev

  DOI：10.1007/bf00473867

  日期：1989.12
• Fluoropyrimidine derivatives
  申请人：Chisso Corporation

  公开号：EP0123907B1

  公开（公告）日：1989-07-26