1-methyl-3-phenylquinoline-2,4(1H,3H)-dione | 92855-76-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-methyl-3-phenylquinoline-2,4(1H,3H)-dione
• 英文别名: 1-methyl-3-phenyl-1H-quinoline-2,4-dione；1-Methyl-3-phenyl-1H-chinolin-2,4-dion；1-Methyl-3-phenyl-chinolin-(1H,3H)-dion-(2,4)；1-Methyl-3-phenylquinoline-2,4-dione
• CAS: 92855-76-0
• 化学式: C₁₆H₁₃NO₂
• 分子量: 251.285
• InChiKey: LRMDUOLQVNJKAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methyl-3-phenylquinoline-2,4(1H,3H)-dione 在 三乙胺 作用下， 以 正己烷 、 二氯甲烷 、 甲苯 为溶剂， 反应 1.0h， 生成 N-methyl-N-(2-(phenylethynyl)phenyl)pentanamide
  参考文献：
  名称：

  Stereodefined Homopropargyl Amines by Tandem Nucleophilic Addition/Fragmentation of Dihydropyridone Triflates

  摘要：

  Dihydropyridone (DHPD) triflates undergo nucleophile-triggered fragmentation to provide homopropargyl amine derivatives, the stereochemistry of which is defined by starting from readily available beta-amino esters.

  DOI：

  10.1021/ol102760q
• 作为产物：
  描述：

  苯乙酰氯 在 4-二甲氨基吡啶 、 sodium hydride 、 potassium carbonate 作用下， 以 四氢呋喃 、 1,4-二氧六环 为溶剂， 反应 1.0h， 生成 1-methyl-3-phenylquinoline-2,4(1H,3H)-dione
  参考文献：
  名称：

  Stereodefined Homopropargyl Amines by Tandem Nucleophilic Addition/Fragmentation of Dihydropyridone Triflates

  摘要：

  Dihydropyridone (DHPD) triflates undergo nucleophile-triggered fragmentation to provide homopropargyl amine derivatives, the stereochemistry of which is defined by starting from readily available beta-amino esters.

  DOI：

  10.1021/ol102760q

文献信息

• Synthesis of [60]Fullerene-Fused Spiroindanes by Palladium-Catalyzed Oxidative Annulation of [60]Fullerene with 2-Aryl Cyclic 1,3-Dicarbonyl Compounds
  作者：Dian-Bing Zhou、Guan-Wu Wang

  DOI：10.1021/acs.orglett.6b01043

  日期：2016.6.3

  A convenient and facile palladium-catalyzed reaction of [60]fullerene (C60) with 2-aryl cyclic 1,3-dicarbonyl compounds via the enolate-directed sp2 C–H activation and sp3 C–H functionalization has been exploited to synthesize the novel and rare C60-fused spiroindanes for the first time. This reaction is easy to perform with broad substrate scope and provides diversified products in 20–50% yields.

  已经开发了一种方便且简便的钯催化的[60]富勒烯（C 60）与2-芳基环状1,3-二羰基化合物通过烯醇化物定向的sp 2 C–H活化和sp 3 C–H官能化反应的方法。首次合成了新颖且稀有的C 60稠合的螺二氢茚。该反应易于在较宽的底物范围内进行，并以20％至50％的产率提供了多种产品。有人提出了一种可行的反应机理，涉及钯催化的烯醇化物定向的CH活化和随后的环化反应，并且还研究了C 60稠合的螺二氢化茚的电化学反应。
• Polarizing plate composition, polarizing plate protective film, polarizer, polarizing plate, and liquid crystal display device
  申请人：FUJIFILM Corporation

  公开号：US10254456B2

  公开（公告）日：2019-04-09

  A polarizing plate composition, a polarizing plate protective film, a polarizer, a polarizing plate, and a liquid crystal display device contain a compound represented by the following Formula (I). In Formula (I), R represents a specific substituent, and each of EWG1 and EWG2 represents an electron-withdrawing group. EWG1 and EWG2 may form a ring by being bonded to each other. Here, there is no such case where EWG1 and EWG2 become the following group by being bonded to each other and form a ring by being bonded to a carbon atom substituted with R. Each of Rx and Ry represents a hydrogen atom or a substituent. * represents a position of bonding to a carbon atom substituted with R.

  一种偏光板组合物、偏光板保护膜、偏光板、偏光板和液晶显示装置含有下式 (I) 所代表的化合物。 在式（I）中，R 代表一个特定的取代基，EWG1 和 EWG2 分别代表一个抽电子基团。EWG1 和 EWG2 可通过相互键合形成一个环。在此，不存在 EWG1 和 EWG2 通过相互键合而成为下一个基团，并通过与被 R 取代的碳原子键合而形成环的情况。 Rx 和 Ry 各自代表氢原子或取代基。* 代表与被 R 取代的碳原子成键的位置。
• Baumgarten; Kaergel, Chemische Berichte, 1927, vol. 60, p. 836
  作者：Baumgarten、Kaergel

  DOI：——

  日期：——
• DE490274
  申请人：——

  公开号：——

  公开（公告）日：——
• POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20160370523A1

  公开（公告）日：2016-12-22

  A polarizing plate composition, a polarizing plate protective film, a polarizer, a polarizing plate, and a liquid crystal display device contain a compound represented by the following Formula (I). In Formula (I), R represents a specific substituent, and each of EWG 1 and EWG 2 represents an electron-withdrawing group. EWG 1 and EWG 2 may form a ring by being bonded to each other. Here, there is no such case where EWG 1 and EWG 2 become the following group by being bonded to each other and form a ring by being bonded to a carbon atom substituted with R. Each of Rx and Ry represents a hydrogen atom or a substituent. * represents a position of bonding to a carbon atom substituted with R.