dodeca-1,11-diene-3,5,7,9-tetrayne | 92070-88-7

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: dodeca-1,11-diene-3,5,7,9-tetrayne
• 英文别名: Dodeca-1,11-dien-3,5,7,9-tetrain；Trideca-1,11-dien-3,5,7,9,-tetrain；Dodeca-1,11-dien-3,5,7,9-tetrayne；dodeca-1,11-dien-3,5,7,9-tetrayne
• CAS: 92070-88-7
• 化学式: C₁₂H₆
• 分子量: 150.18
• InChiKey: MDDRTXZQDSBSIN-UHFFFAOYSA-N

物化性质

• 熔点：
  38-40 °C(Solv: hexane (110-54-3))
• 沸点：
  236.2±23.0 °C(Predicted)
• 密度：
  1.001±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  hex-1-ene-3,5-diyne 在 水 、 丙酮 、 copper(l) chloride 作用下， 生成 dodeca-1,11-diene-3,5,7,9-tetrayne
  参考文献：
  名称：

  Swallowing Disorders in the Elderly

  摘要：

  AbstractChanges that occur as a natural part of senescence in the complex action of deglutition predispose us to dysphagia and aspiration. As the “baby‐boomers” begin to age, the onset of swallowing difficulties will begin to manifest in a greater number of our population. Recent advances in the evaluation of normal and abnormal swallowing make possible more precise anatomical and physiological diagnoses. Coupled with an understanding of swallowing physiology, such detailed evaluation allows greater opportunity to safely manage dysphagia with directed therapy and appropriate surgical intervention. The current study is a discussion of the changes that occur in deglutition with normal aging, contemporary evaluation of swallowing function, and some of the common causes of dysphagia in elderly patients.

  DOI：

  10.1097/00005537-200204000-00001

文献信息

• Swallowing Disorders in the Elderly
  作者：Joshua S. Schindler、James H. Kelly

  DOI：10.1097/00005537-200204000-00001

  日期：2002.4

  AbstractChanges that occur as a natural part of senescence in the complex action of deglutition predispose us to dysphagia and aspiration. As the “baby‐boomers” begin to age, the onset of swallowing difficulties will begin to manifest in a greater number of our population. Recent advances in the evaluation of normal and abnormal swallowing make possible more precise anatomical and physiological diagnoses. Coupled with an understanding of swallowing physiology, such detailed evaluation allows greater opportunity to safely manage dysphagia with directed therapy and appropriate surgical intervention. The current study is a discussion of the changes that occur in deglutition with normal aging, contemporary evaluation of swallowing function, and some of the common causes of dysphagia in elderly patients.