4-(hexadecyloxy)benzyl alcohol | 212627-69-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-(hexadecyloxy)benzyl alcohol
• 英文别名: 4-Hexadecyloxybenzyl alcohol；(4-hexadecoxyphenyl)methanol
• CAS: 212627-69-5
• 化学式: C₂₃H₄₀O₂
• 分子量: 348.569
• InChiKey: XVICRUCHPCJPFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(hexadecyloxy)benzyl alcohol 在 氯化亚砜 、 N,N-二甲基甲酰胺 作用下， 以 四氢呋喃 为溶剂， 反应 5.0h， 生成 4-hexadecyloxybenzyl chloride
  参考文献：
  名称：

  Effect of central linkages on mesophase behavior of imidazolium-based rod-like ionic liquid crystals

  摘要：

  合成了两系列基于苯基苄醚和苯腈的棒状咪唑鎓溴化物及其非离子前体1-苯基-1H-咪唑，并研究了烷基链的数量和长度以及芳香核心中连接基团（–CH2O–、–COO–、–CONH–）的结构对其在离子液晶相中的介相自组装的影响，采用了偏光显微镜（POM）、差示扫描量热仪（DSC）和X射线衍射（XRD）等技术。当减少N-末端链的长度或增加C-末端链的数量和长度时，对于基于醚的咪唑鎓盐，发现了层状相（SmA）–六角柱状相（Colhex）–胶束立方相（CubI/Pm3n）的序列；而相关的酰胺仅观察到SmA和Colhex相。讨论了中心链接的极性（即–CH2O–和–CONH–）对介相结构和稳定性影响，并与相关的–COO–连接的离子液晶进行了比较。

  DOI：

  10.1039/c2sm06854k
• 作为产物：
  描述：

  4-(十六烷氧基)苯甲醛 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 生成 4-(hexadecyloxy)benzyl alcohol
  参考文献：
  名称：

  Positional and Charged Effects of Heterocyclic N Atoms on Mesogenic Properties of Stilbazoles and Analogous N-Oxides

  摘要：

  The synthesis and the phase behavior of stilbazoles and corresponding N-oxides containing different positions of heterocyclic N atoms, i.e. trans-2'-, 3'-, 4'- stilbazoles and their N-oxides, are reported. Their phase transition temperatures and the mesogenic behavior were investigated through the DSC, polarizing optical microscope and X-ray diffraction (XRD) measurements. Increasing dipole moments by oxidation of stilbazoles to analogous N-oxides induces the S-A phase with an interdigitated bilayer packing. Both 2'-stilbazoles and analogous N-oxides do not possess mesogenic phases, which may be due that pi electron polarizabilities an reduced by the molecular twist originated from dipoles along the ortho-direction. Besides, the positonal effects of the N-oxides on mesogenic properties are more distinct than those of analogous stilbazoles, and new mesogenic phases have been generated by tuning the position of the N-oxide function in the charged liquid crystals. Consequently, unique mesogenic properties may he introduced through adjusting the dipolar direction and strength of the heterocyclic atoms in the molecules.

  DOI：

  10.1080/10587250008031032

文献信息

• 1-(4-Alkyloxybenzyl)-3-methyl-<i>1H</i>-imidazol-3-ium organic backbone: A versatile smectogenic moiety
  作者：William Dobbs、Laurent Douce、Benoît Heinrich

  DOI：10.3762/bjoc.5.62

  日期：——

  The merger of ionic liquid and liquid crystal fields, obtained by using the imidazolium ring as a common element, has allowed us to tailor a new set of materials which associate specific functionalities. These functionalities are consequences of the original properties of the component, ionic liquids, liquid crystals and their association in a single compound. The study of this interesting association led us to elaborate environment-flexible cationic architectures from which mesomorphic properties emerge. Moreover, we have also explored the influence of different anions on the mesomorphic properties.

  离子液体和液晶领域的合并，通过使用咪唑环作为共同元素，使我们能够定制一组新材料，这些材料具有特定的功能。这些功能是组分的原始性质——离子液体、液晶及它们在单一化合物中的结合——的结果。对这种有趣的结合的研究使我们能够从中制定出环境灵活的阳离子结构，从中产生出介向性质。此外，我们还探讨了不同阴离子对介向性质的影响。
• Effect of central linkages on mesophase behavior of imidazolium-based rod-like ionic liquid crystals
  作者：Xiaohong Cheng、Fawu Su、Rong Huang、Hongfei Gao、Marko Prehm、Carsten Tschierske

  DOI：10.1039/c2sm06854k

  日期：——

  Two series of phenylbenzylether and benzanilide based rod-like imidazolium bromides and their nonionic precursors, the 1-phenyl-1H-imidazoles have been synthesized and the influence of the number and length of the alkyl chain(s) and the structure of the linking group in the aromatic core (–CH2O–, –COO–, –CONH–) on their mesophase self-assembly in ionic liquid crystalline phases were studied by POM, DSC and XRD. Upon decreasing the length of the N-terminal chain or by enlarging the number and length of the C-terminal chains, the sequence smectic (SmA)–hexagonal columnar (Colhex)–micellar cubic (CubI/Pm3n) was found for the ether based imidazolium salts; while only SmA and Colhex phases were observed for the related amides. The influence of the polarity of the central linkages, namely –CH2O– and –CONH–, on the mesophase structure and stability is discussed and compared with related –COO– connected ILC.

  合成了两系列基于苯基苄醚和苯腈的棒状咪唑鎓溴化物及其非离子前体1-苯基-1H-咪唑，并研究了烷基链的数量和长度以及芳香核心中连接基团（–CH2O–、–COO–、–CONH–）的结构对其在离子液晶相中的介相自组装的影响，采用了偏光显微镜（POM）、差示扫描量热仪（DSC）和X射线衍射（XRD）等技术。当减少N-末端链的长度或增加C-末端链的数量和长度时，对于基于醚的咪唑鎓盐，发现了层状相（SmA）–六角柱状相（Colhex）–胶束立方相（CubI/Pm3n）的序列；而相关的酰胺仅观察到SmA和Colhex相。讨论了中心链接的极性（即–CH2O–和–CONH–）对介相结构和稳定性影响，并与相关的–COO–连接的离子液晶进行了比较。
• Amphiphilic dendritic dipeptides & their self-assembly into helical pores
  申请人：Percec Virgil

  公开号：US20060088499A1

  公开（公告）日：2006-04-27

  An amphiphilic dendritic dipeptide, comprises a dipeptide(s) comprising one or more of a naturally occurring or synthetic amino acids and a dendron. These are suitable for use in various formulations, films, coatings, membranes and sensors, among other applications.

  一种两性树状二肽，包括一个或多个天然存在或合成氨基酸的二肽和一个树状结构。这些适用于各种配方、薄膜、涂层、膜和传感器等应用。
• Helical Porous Protein Mimics Self-Assembled from Amphiphilic Dendritic Dipeptides
  作者：Virgil Percec、Andrés Dulcey、Mihai Peterca、Monica Ilies、Yoshiko Miura、Ulrica Edlund、Paul A. Heiney

  DOI：10.1071/ch05092

  日期：——

  This manuscript reports the synthesis and the self-assembly of (4-3,4,5-3,5)nG2-CH2-Boc-l-Tyr-l-Ala-OMe dendritic dipeptides (n = 12, 16). These dendritic dipeptides self-assemble both in solution and in solid states into helical porous supramolecular columns that mimic porous transmembrane proteins. These supramolecular assemblies provide also a new class of tubular supramolecular polymers.

  本手稿报告了(4-3,4,5-3,5)nG2-CH2-Boc-l-Tyr-l-Ala-OMe树枝状二肽（n = 12，16）的合成和自组装。这些树枝状二肽在溶液和固体状态下都能自组装成螺旋多孔超分子柱，模拟多孔跨膜蛋白。这些超分子组装物还提供了一类新的管状超分子聚合物。
• Amphiphilic dendritic dipeptides and their self-assembly into helical pores
  申请人：The Trustees of The University of Pennsylvania

  公开号：US07671033B2

  公开（公告）日：2010-03-02

  An amphiphilic dendritic dipeptide, comprises a dipeptide(s) comprising one or more of a naturally occurring or synthetic amino acids and a dendron. These are suitable for use in various formulations, films, coatings, membranes and sensors, among other applications.

  一种亲水疏水两性树枝二肽，包含一个由一种或多种天然或合成氨基酸组成的二肽和一个树枝。这些适用于各种配方、薄膜、涂层、膜和传感器等应用。