methyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate | 1331942-98-3
分子结构分类
中文名称
——
中文别名
——
英文名称
methyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate
英文别名
——
CAS
1331942-98-3
化学式
C19H16FNO3
mdl
——
分子量
325.339
InChiKey
IRQIASHUOPLPQD-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
-
物化性质
-
计算性质
-
ADMET
-
安全信息
-
SDS
-
制备方法与用途
-
上下游信息
-
文献信息
-
表征谱图
-
同类化合物
-
相关功能分类
-
相关结构分类
物化性质
-
沸点：490.5±45.0 °C(Predicted)
-
密度：1.333±0.06 g/cm3(Predicted)
计算性质
-
辛醇/水分配系数(LogP)：4.2
-
重原子数：24
-
可旋转键数：4
-
环数：4.0
-
sp3杂化的碳原子比例：0.21
-
拓扑面积：65.5
-
氢给体数：1
-
氢受体数：5
上下游信息
-
上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— methyl 5-cyclopropyl-2-(4-fluorophenyl)-6-nitro-1-benzofuran-3-carboxylate 1331942-97-2 C19H14FNO5 355.322 —— methyl 2-(4-fluorophenyl)-5-hydroxy-6-nitro-1-benzofuran-3-carboxylate 1331942-95-0 C16H10FNO6 331.257 —— methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate 691856-96-9 C16H11FO4 286.259 —— methyl 2-(4-fluorophenyl)-5-[(1-methylethyl)oxy]-1-benzofuran-3-carboxylate 1331942-87-0 C19H17FO4 328.34 —— methyl 2-(4-fluorophenyl)-5-[(1-methylethyl)oxy]-6-nitro-1-benzofuran-3-carboxylate 1331942-88-1 C19H16FNO6 373.338 —— methyl 2-(4-fluorophenyl)-6-nitro-5-{[(trifluoromethyl)sulfonyl]oxy}-1-benzofuran-3-carboxylate 1331942-96-1 C17H9F4NO8S 463.32 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 5-环丙基-2-(4-氟苯基)-6-[(甲基磺酰基)氨基]-1-苯并呋喃-3-羧酸 5-cyclopropyl-2-(4-fluorophenyl)-6-[(methylsulfonyl)amino]-1-benzofuran-3-carboxylic acid 691857-54-2 C19H16FNO5S 389.404 —— methyl 6-[bis(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate 1331942-99-4 C21H20FNO7S2 481.523 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxamide 1331945-03-9 C19H17FN2O4S 388.419 5-环丙基-2-(4-氟苯基)-N-甲基-6-(甲基磺酰氨基)苯并呋喃-3-甲酰胺 5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)benzofuran-3-carboxamide 691856-35-6 C20H19FN2O4S 402.446 —— N-(2-(benzyloxy)ethyl)-5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxamide 1378429-42-5 C28H27FN2O5S 522.597 —— 5-cyclopropyl-2-(4-fluorophenyl)-N-isopropyl-6-(methylsulfonamido)benzofuran-3-carboxamide 1378429-37-8 C22H23FN2O4S 430.5 —— N,5-dicyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxamide 1378429-90-3 C22H21FN2O4S 428.484 —— 4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenylboronic acid 1423007-35-5 C26H24BFN2O6S 522.362 —— 6-(N-(3-bromophenyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1423007-39-9 C26H22BrFN2O4S 557.44 —— ((4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yI)methylsulfonamido)phenoxy)methyl)boronic acid 1423007-94-6 C27H26BFN2O7S 552.388 —— (3-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenethyl)boronic acid 1423008-28-9 C28H28BFN2O6S 550.416 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-[(3-hydroxypropyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 1378428-65-9 C23H25FN2O5S 460.526 —— 5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-((methylsulfonyl){3-[(phenylmethyl)oxy]propyl}amino)-1-benzofuran-3-carboxamide 1378428-63-7 C30H31FN2O5S 550.651 —— 4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-2-fluorophenylboronic acid 1423007-41-3 C26H23BF2N2O6S 540.352 —— 3-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenylboronic acid 1423007-38-8 C26H24BFN2O6S 522.362 —— (4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-2,6-difluorophenyl)boronic acid 1423007-67-3 C26H22BF3N2O6S 558.343 —— 6-(N-(2-(benzyloxymethyl)allyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)benzofuran-3-carboxamide 1378430-02-4 C30H29FN2O5S 548.635 —— [({3-[{5-cyclopropyl-2-(4-fluorophenyl)-3-[(methylamino)carbonyl]-1-benzofuran-6-yl}(methylsulfonyl)amino]propyl}oxy)methyl]boronic acid 1378427-20-3 C24H28BFN2O7S 518.371 —— 6-(N-(3-(benzyloxymethyl)but-3-enyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378429-05-0 C32H33FN2O5S 576.689 —— (2-cyano-4-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}phenyl)boronic acid 1423007-71-9 C27H23BFN3O6S 547.372 —— (2-chloro-4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenethyl)boronic acid 1423008-15-4 C28H27BClFN2O6S 584.861 —— (2-chloro-4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenyl)boronic acid 1423007-27-5 C26H23BClFN2O6S 556.807 —— 6-[{[4-bromo-3-(hydroxymethyl)phenyl]methyl}(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 1331944-86-5 C28H26BrFN2O5S 601.493 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-((2-hydroxy-1,2-oxaborolan-4-yl)methyl)methylsulfonamido)benzofuran-3-carboxamide 1378427-58-7 C23H24BFN2O6S 486.329 —— 6-[{[4-bromo-3-fluoro-5-(hydroxymethyl)phenyl]methyl}(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxamide 1378432-29-1 C27H23BrF2N2O5S 605.457 —— methyl 2-bromo-4-{[{5-cyclopropyl-2-(4-fluorophenyl)-3-[(methylamino)carbonyl]-1-benzofuran-6-yl}(methylsulfonyl)amino]methyl}benzoate 1378428-55-7 C29H26BrFN2O6S 629.504 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)methylsulfonamido)-N-methylbenzofuran-3-carboxamide 1423008-00-7 C27H24BFN2O6S 534.373 —— 5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-[(methylsulfonyl)(2-{[(phenylmethyl)oxy]methyl}-2-propen-1-yl)amino]-1-benzofuran-3-carboxamide 1378428-61-5 C31H31FN2O5S 562.662 —— 6-(N-(2-(benzyloxymethyl)but-3-enyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378429-16-3 C32H33FN2O5S 576.689 —— 5-cyclopropyl-6-(N-(2-fluoro-4-nitrophenyl)methylsulfonamido)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1423007-47-9 C26H21F2N3O6S 541.532 —— 6-(N-(4-(benzyloxy)-3-chlorophenyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1423007-98-0 C33H28ClFN2O5S 619.113 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-[[2-(2-hydroxy-1,2-oxaborolan-5-yl)ethyl](methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 1378427-38-3 C25H28BFN2O6S 514.383 —— ((2-chloro-4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)phenoxy)methyl)boronic acid 1423007-97-9 C27H25BClFN2O7S 586.833 —— 4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-3-fluorophenylboronic acid 1423007-46-8 C26H23BF2N2O6S 540.352 —— 6-(N-(4-(benzyloxy)-2-methylenebutyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378428-97-7 C32H33FN2O5S 576.689 —— 6-(N-(3-(2-bromo-4-fluorophenyl)-3-hydroxypropyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378433-22-7 C29H27BrF2N2O5S 633.511 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-(2-(2-hydroxy-1,2-oxaborolan-4-yl)ethyl)methylsulfonamido)-N-methylbenzofuran-3-carboxamide 1378427-36-1 C25H28BFN2O6S 514.383 —— 6-(N-(2-(benzyloxy)but-3-enyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378429-33-4 C31H31FN2O5S 562.662 —— 6-(N-(3-(2-bromo-5-fluorophenyl)-3-hydroxypropyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 1378433-13-6 C29H27BrF2N2O5S 633.511 —— methyl 2-bromo-5-{[{5-cyclopropyl-2-(4-fluorophenyl)-3-[(methylamino)carbonyl]-1-benzofuran-6-yl}(methylsulfonyl)amino]methyl}benzoate 1331944-84-3 C29H26BrFN2O6S 629.504 —— 6-[[3-(2-bromo-4-chlorophenyl)-3-hydroxypropyl](methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 1378432-53-1 C29H27BrClFN2O5S 649.965 —— 6-[{[4-bromo-3-fluoro-5-({[(methyloxy)methyl]oxy}methyl)phenyl]methyl}(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxamide 1378432-31-5 C29H27BrF2N2O6S 649.51 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-[{[(4R)-2-hydroxy-1,2-oxaborolan-4 yl]methyl}(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 1378427-18-9 C24H26BFN2O6S 500.356 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-[{[(4S)-2-hydroxy-1,2-oxaborolan-4 yl]methyl}(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 1378427-19-0 C24H26BFN2O6S 500.356 —— 5-cyclopropyl-2-(4-fluorophenyl)-6-[[(2-hydroxy-1,2-oxaborolan-4-yl)methyl](methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 1378427-17-8 C24H26BFN2O6S 500.356 —— (4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-2-(trifluoromethyl)phenyl)boronic acid 1423007-63-9 C27H23BF4N2O6S 590.36 —— (4-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-2-(difluoromethyl)phenyl)boronic acid 1423007-59-3 C27H24BF3N2O6S 572.37 —— 6-[[(4-bromo-3-formylphenyl)methyl](methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 1378431-72-1 C28H24BrFN2O5S 599.477 —— 6-(N-(3-(benzyloxy)-2-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)propyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)benzofuran-3-carboxamide 1378430-04-6 C36H42BFN2O7S 676.614 —— methyl 2-(5-(N-(5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-6-yl)methylsulfonamido)-2-nitrophenyl)acetate 1423008-47-2 C29H26FN3O8S 595.605