2,3,4-tri-O-allyl-L-arabinitol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4-tri-O-allyl-L-arabinitol
• 英文别名: 2,3,4-tri-O-allyl-l-arabinitol；(2S,4S)-2,3,4-tris(prop-2-enoxy)pentane-1,5-diol
• 化学式: C₁₄H₂₄O₅
• 分子量: 272.342
• InChiKey: CVPHGOZHGAXIDL-STQMWFEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  L-(-)-arabitol 在 吡啶 、 silica gel 、 sodium hydride 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 6.0h， 生成 2,3,4-tri-O-allyl-L-arabinitol
  参考文献：
  名称：

  基于L-阿拉伯糖醇的功能性聚氨酯

  摘要：

  从L-阿拉伯糖醇制备了三种基于单-，二-和三-O-烯丙基L-阿拉伯糖醇衍生物的新型可聚合二醇，作为通用材料，用于制备具有不同官能度的量身定制的聚氨酯。它们的烯丙基官能团可以参与硫醇反应，从而获得种类繁多的材料。首先在高度受阻的糖前体2,3,4- tri - O-烯丙基-1,5 - di - O-三苯甲基-L-阿拉伯糖醇上研究了与2-巯基乙醇的“点击”反应，随后将其应用于大分子。通过2,3,4-三-O-烯丙基-L的加成反应合成了具有多个烯丙基侧基的聚氨酯阿拉伯糖醇与1,6-己二异氰酸酯，然后通过硫醇反应进行官能化。如标准技术所证实的，偶联反应在每个烯丙基中发生。通过热重分析和差示扫描量热法（DSC）研究了新型聚氨酯的热稳定性。该策略为设计新材料提供了一个简单而通用的平台，其功能可以轻松修改。©2010 Wiley Periodicals，Inc. J Polym Sci A部分：Polym Chem，2011年

  DOI：

  10.1002/pola.24530

文献信息

• Method for functionalising a thermoset, crosslinked isocyanate-based polymeric solid material.
  申请人：Recticel

  公开号：EP2522685A2

  公开（公告）日：2012-11-14

  The invention relates to a method for functionalising a thermoset, crosslinked isocyanate-based polymeric solid material which is made of isocyanate and isocyanate reactive components, at least one of which comprises an anchor component which has at least one anchor group. The anchor groups on the solid material are formed by terminal alkene and/or alkyne groups. To functionalise this polymeric solid material it is brought in contact with a solution which contains at least one functional component. This functional component comprises at least one thiol group and is allowed to bind covalently to the polymeric solid material by a free-radical addition reaction between the thiol groups on the functional component and the terminal alkene and/or alkyne anchor groups on the undissolved solid material. An effective functionalisation of the polymeric material can thus be achieved notwithstanding the heterogeneous reaction conditions.

  本发明涉及一种对热固性交联异氰酸酯基聚合物固体材料进行功能化的方法，该固 体材料由异氰酸酯和异氰酸酯反应组分组成，其中至少一种组分包括一个锚定组分，该 锚定组分具有至少一个锚定基团。固体材料上的锚基由端烯基和/或炔基形成。为了使这种聚合固体材料功能化，需要将其与含有至少一种功能成分的溶液接触。这种官能团至少包含一个硫醇基团，通过官能团上的硫醇基团与未溶解固体材料上的末端烯基和/或炔基锚基团之间的自由基加成反应，使其与聚合物固体材料共价结合。因此，尽管存在异构反应条件，但仍可实现聚合物材料的有效官能化。
• Method for functionalising a thermoset isocyanate-based polymeric solid material.
  申请人：Recticel

  公开号：EP2522684A1

  公开（公告）日：2012-11-14

  The invention relates to a method for functionalising a thermoset isocyanate-based polymeric solid material which is made of isocyanate and isocyanate reactive components, at least one of which comprises an anchor component which has at least one anchor group. The anchor groups on the solid material are formed by terminal alkene and/or alkyne groups. To functionalise this polymeric solid material it is brought in contact with a solution which contains at least one functional component. This functional component comprises at least one thiol group and is allowed to bind covalently to the polymeric solid material by a free-radical addition reaction between the thiol groups on the functional component and the terminal alkene and/or alkyne anchor groups on the solid material. An effective functionalisation of the polymeric material can thus be achieved notwithstanding the heterogeneous reaction conditions.

  本发明涉及一种热固性异氰酸酯基聚合物固体材料的功能化方法，该固体材料由异氰酸酯和异氰酸酯反应组分组成，其中至少一种组分包括一个锚定组分，该锚定组分具有至少一个锚定基团。固体材料上的锚基由端烯基和/或炔基形成。为了使这种聚合固体材料功能化，需要将其与含有至少一种功能成分的溶液接触。这种官能团至少包含一个硫醇基团，并通过官能团上的硫醇基团与固体材料上的末端烯基和/或炔基锚基团之间的自由基加成反应，与聚合物固体材料共价结合。因此，尽管存在异构反应条件，但仍可实现聚合物材料的有效官能化。
• METHOD FOR FUNCTIONALISING A THERMOSET, CROSSLINKED ISOCYANATE-BASED POLYMERIC SOLID MATERIAL
  申请人：JONCKHEERE Laura

  公开号：US20120289621A1

  公开（公告）日：2012-11-15

  The invention relates to a method for functionalising a thermoset, crosslinked isocyanate-based polymeric solid material which is made of isocyanate and isocyanate reactive components, at least one of which comprises an anchor component which has at least one anchor group. The anchor groups on the solid material are formed by terminal alkene and/or alkyne groups. To functionalise this polymeric solid material it is brought in contact with a solution which contains at least one functional component. This functional component comprises at least one thiol group and is allowed to bind covalently to the polymeric solid material by a free-radical addition reaction between the thiol groups on the functional component and the terminal alkene and/or alkyne anchor groups on the undissolved solid material. An effective functionalisation of the polymeric material can thus be achieved notwithstanding the heterogeneous reaction conditions.
• US8901180B2
  申请人：——

  公开号：US8901180B2

  公开（公告）日：2014-12-02
• <scp>L</scp> ‐arabinitol‐based functional polyurethanes
  作者：Cristina Ferris、M. Violante de Paz、Juan A. Galbis

  DOI：10.1002/pola.24530

  日期：2011.3

  Three new polymerizable diols, based on mono‐, di‐, and tri‐O‐allyl‐L‐arabinitol derivatives, were prepared from L‐arabinitol as versatile materials for the preparation of tailor‐made polyurethanes with varied degrees of functionalization. Their allyl functional groups can take part in thiol‐ene reactions, to obtain greatly diverse materials. This “click” reaction with 2‐mercaptoethanol was firstly

  从L-阿拉伯糖醇制备了三种基于单-，二-和三-O-烯丙基L-阿拉伯糖醇衍生物的新型可聚合二醇，作为通用材料，用于制备具有不同官能度的量身定制的聚氨酯。它们的烯丙基官能团可以参与硫醇反应，从而获得种类繁多的材料。首先在高度受阻的糖前体2,3,4- tri - O-烯丙基-1,5 - di - O-三苯甲基-L-阿拉伯糖醇上研究了与2-巯基乙醇的“点击”反应，随后将其应用于大分子。通过2,3,4-三-O-烯丙基-L的加成反应合成了具有多个烯丙基侧基的聚氨酯阿拉伯糖醇与1,6-己二异氰酸酯，然后通过硫醇反应进行官能化。如标准技术所证实的，偶联反应在每个烯丙基中发生。通过热重分析和差示扫描量热法（DSC）研究了新型聚氨酯的热稳定性。该策略为设计新材料提供了一个简单而通用的平台，其功能可以轻松修改。©2010 Wiley Periodicals，Inc. J Polym Sci A部分：Polym Chem，2011年