7-苯氧基-庚酸 | 7170-42-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 7-苯氧基-庚酸
• 英文名称: 7-Phenoxy-heptansaeure
• 英文别名: 7-Phenoxyheptanoic acid
• CAS: 7170-42-5
• 化学式: C₁₃H₁₈O₃
• 分子量: 222.284
• InChiKey: XAKQRRNXHLDJNZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  7-苯氧基-庚酸 在 氢溴酸 作用下， 生成 7-溴庚酸
  参考文献：
  名称：

  Gaubert; Linstead; Rydon, Journal of the Chemical Society, 1937, p. 1977

  摘要：

  DOI：
• 作为产物：
  描述：

  7-溴庚酸甲酯 在 sodium hydroxide 、 potassium carbonate 作用下， 以 乙醇 、 环己酮 为溶剂， 反应 6.0h， 生成 7-苯氧基-庚酸
  参考文献：
  名称：

  胆固醇基ω-芳基链烷酸酯的液晶性质

  摘要：

  DOI：

  10.1021/j150655a041

文献信息

• [EN] 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS<br/>[FR] AGENTS ANTIFONGIQUES À BASE DE 2-AMINO-1,3,4-THIADIAZINE ET DE 2-AMINO-1,3,4-OXADIAZINE
  申请人：F2G LTD

  公开号：WO2017009651A1

  公开（公告）日：2017-01-19

  The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N', C', A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.

  该发明提供了一种化合物，其为式(I)的二氮杂环化合物或其互变异构体，或其药学上可接受的盐，用作抗真菌剂：(I)其中X、N'、C'、A和E如本文所定义。该发明还提供了一种如本文所定义的式(I)的化合物。
• [EN] AMINOACID LIPIDS<br/>[FR] LIPIDES D'ACIDES AMINÉS
  申请人：MERCK PATENT GMBH

  公开号：WO2013135360A1

  公开（公告）日：2013-09-19

  The present invention is directed to a new class of lipids, more specifically ether-lipids having a polar headgroup, as well as vesicles comprising these lipids, methods of their preparation as well as their uses in medical applications, wherein the ether-lipids are represented by general formula (I) wherein Y represents O, N, S or a covalent bond; P1 represents H, an Y- protecting group or an Y-activating group or a spacer group; P2, P3 represent independently of each other H, an amino-protecting group or a spacer group, or P2 and P3 form together with the N to which they are bound a ring structure; L is a group of formula (a) wherein the dashed line represents the linkage to N; R1 represents H or a group of formula -(CH2)2-ORb1; R1 represents H or a group of formula - (CH2)2-ORb2, R2 represents H or a group of formula -CH2-ORc; R2 Represents H or a group of formula -ORd or -CH2-ORc,' R2 represents H or a group of formula -(CH2)2-ORe or -(CH2)3-ORe; Ra, Rb1, Rb2, Rc, Rd,Re represent independently of each other a saturated or unsaturated, straight or branched hydrocarbon chain, and m is 1, 2 or 3; with the proviso that at least one of R1, R1', R2, R2', R3 is not H.

  本发明涉及一种新型脂类，更具体地说是具有极性头基团的醚脂类，以及包含这些脂类的囊泡、它们的制备方法以及它们在医学应用中的用途，其中醚脂类由通式（I）表示，其中Y代表O、N、S或共价键；P1表示H、一个Y-保护基或Y-活化基或空间基；P2、P3独立地表示H、氨基保护基或空间基，或者P2和P3与它们所结合的N一起形成一个环状结构；L是一个式子（a）的基团，其中虚线表示与N的连接；R1表示H或一个式子-(CH2)2-ORb1的基团；R1表示H或一个式子-( )2-ORb2的基团，R2表示H或一个式子- -ORc的基团；R2表示H或一个式子-ORd或- -ORc的基团，R2表示H或一个式子-( )2-ORe或-( )3-ORe的基团；Ra、Rb1、Rb2、Rc、Rd、Re独立地表示饱和或不饱和的直链或支链烃链，m为1、2或3；但至少有一个R1、R1'、R2、R2'、R3不是H。
• Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20040067576A1

  公开（公告）日：2004-04-08

  A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): A m B (1−m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or larger and smaller than 1: 1 wherein n has a value of 0 to 10, k has a value of 3 or 5, and R is at least one group selected from the group consisting of groups represented by General Formulae (5) to (7): 2 in Formula (5) R1 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 . and —C 3 F 7 ; and q is an integer selected from 1 to 8; in Formula (6) R2 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 ; and r is an integer selected from 1 to 8; in Formula (7) R3 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 ; and s is an integer selected from 1 to 8. The efficient production methods are also provided.

  一种聚羟基脂肪酸酯，其单体单元组成由通式（1）表示：AmB（1-m）（1）其中，A由通式（2）表示，B至少选自通式（3）或（4）表示的单体单元组成的群体，m的值大于或等于0.01且小于1:1。其中n的值为0到10，k的值为3或5，R至少选自通式（5）到（7）表示的群体中的一种：2在公式（5）中，R1选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的群体，q为1到8之间的整数；在公式（6）中，R2选自氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的群体，r为1到8之间的整数；在公式（7）中，R3选自氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的群体，s为1到8之间的整数。同时还提供了高效的生产方法。
• Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms
  申请人：——

  公开号：US20010029039A1

  公开（公告）日：2001-10-11

  A microbial polyhydroxyalkanoate which comprises one or more of monomer units represented by Formula (1), 1 where R is at least one selected from the group represented by any one of Formulas (2), (3) and (4); 2 in Formula (2), R1 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and q is an integer of 1 to 8; in Formula (3), R2 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and r is an integer of 1 to 8; in Formula (4), R3 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and s is an integer of 1 to 8. The production method is also disclosed.

  一种微生物聚羟基烷酸酯，包括由式（1）表示的单体单元中的一个或多个，其中R至少选自式（2）、（3）和（4）所表示的任一组中的一种；在式（2）中，R1选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的一组中，q是1到8的整数；在式（3）中，R2选自氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的一组中，r是1到8的整数；在式（4）中，R3选自氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的一组中，s是1到8的整数。同时公开了生产方法。
• Process for producing polyhydroxyalkanoates by utilizing microorganisms
  申请人：——

  公开号：US20030180899A1

  公开（公告）日：2003-09-25

  A microbial polyhydroxyalkanoate which comprises one or more of monomer units represented by Formula (1), 1 where R is at least one selected from the group represented by any one of Formulas (2), (3) and (4); 2 in Formula (2), R1 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and q is an integer of 1 to 8; in Formula (3), R2 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and r is an integer of 1 to 8; in Formula (4), R3 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and s is an integer of 1 to 8. The production method is also disclosed.

  一种微生物聚羟基脂肪酸酯，包括由公式（1）表示的单体单元中的一个或多个，其中R至少选自任一公式（2）、（3）和（4）所表示的组中之一；在公式（2）中，R1从氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的组中选择，q为1至8的整数；在公式（3）中，R2从氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的组中选择，r为1至8的整数；在公式（4）中，R3从氢原子（H）、卤素原子、—CN、— 、— 、— 和— 组成的组中选择，s为1至8的整数。还公开了生产方法。