2,4-dibenzoylpyridine | 501938-32-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4-dibenzoylpyridine
• 英文别名: 2,4-dibenzoyl-pyridine；2,4-Dibenzoyl-pyridin；(2-Benzoylpyridin-4-yl)-phenylmethanone
• CAS: 501938-32-5
• 化学式: C₁₉H₁₃NO₂
• 分子量: 287.318
• InChiKey: KFGGLOLUGGBEDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  47
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,4-dibenzoylpyridine 在 sodium tetrahydroborate 、 三乙胺 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 72.0h， 生成
  参考文献：
  名称：

  Aromatic and Nonaromatic Pyriporphyrins

  摘要：

  Pyriporphyrins with three different orientations for the pyridine moiety have been prepared using a '3 + 1' strategy. The nonaromatic pyriporphyrins are stable so long as phenyl substituents are present at the meso-positions adjacent to the pyridine ring. An aromatic dihydropyriporphyrin with an external CO2Ph protective group has also been prepared from 2,4-pyridinedicarbaldehyde.

  DOI：

  10.1021/ol071052x
• 作为产物：
  描述：

  2,4-吡啶二羧酸 在 三氯化铝 、 氯化亚砜 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 17.0h， 生成 2,4-dibenzoylpyridine
  参考文献：
  名称：

  Aromatic and Nonaromatic Pyriporphyrins

  摘要：

  Pyriporphyrins with three different orientations for the pyridine moiety have been prepared using a '3 + 1' strategy. The nonaromatic pyriporphyrins are stable so long as phenyl substituents are present at the meso-positions adjacent to the pyridine ring. An aromatic dihydropyriporphyrin with an external CO2Ph protective group has also been prepared from 2,4-pyridinedicarbaldehyde.

  DOI：

  10.1021/ol071052x

文献信息

• Tsuda et al., Pharmaceutical Bulletin, 1953, vol. 1, p. 307,316
  作者：Tsuda et al.

  DOI：——

  日期：——
• Aromatic and Nonaromatic Pyriporphyrins
  作者：Timothy D. Lash、Komal Pokharel、Jill M. Serling、Valerie R. Yant、Gregory M. Ferrence

  DOI：10.1021/ol071052x

  日期：2007.7.1

  Pyriporphyrins with three different orientations for the pyridine moiety have been prepared using a '3 + 1' strategy. The nonaromatic pyriporphyrins are stable so long as phenyl substituents are present at the meso-positions adjacent to the pyridine ring. An aromatic dihydropyriporphyrin with an external CO2Ph protective group has also been prepared from 2,4-pyridinedicarbaldehyde.