(3,5-Bis-{3,5-bis-[4-(tetrahydro-pyran-2-yloxymethyl)-benzyloxy]-benzyloxy}-phenyl)-methanol | 850479-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (3,5-Bis-{3,5-bis-[4-(tetrahydro-pyran-2-yloxymethyl)-benzyloxy]-benzyloxy}-phenyl)-methanol
• CAS: 850479-53-7
• 化学式: C₇₃H₈₄O₁₅
• 分子量: 1201.46
• InChiKey: YZAYTCHTHBDCMQ-UHFFFAOYSA-N

物化性质

• 密度：
  1.27±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  14.83
• 重原子数：
  88.0
• 可旋转键数：
  31.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  149.45
• 氢给体数：
  1.0
• 氢受体数：
  15.0

反应信息

• 作为反应物：
  描述：

  (3,5-Bis-{3,5-bis-[4-(tetrahydro-pyran-2-yloxymethyl)-benzyloxy]-benzyloxy}-phenyl)-methanol 在 四溴化碳 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 反应 0.25h， 以95%的产率得到2,2',2'',2'''-(((((((((5-(bromomethyl)-1,3-phenylene)bis(oxy))bis(methylene))bis(benzene-5,1,3-triyl))tetrakis(oxy))tetrakis(methylene))tetrakis(benzene-4,1-diyl))tetrakis(methylene))tetrakis(oxy))tetrakis(tetrahydro-2H-pyran)
  参考文献：
  名称：

  Synthesis and Direct Visualization of Block Copolymers Composed of Different Macromolecular Architectures

  摘要：

  A novel approach toward the synthesis of block copolymers composed of architecturally different components, in this case, a nanoparticle covalently attached to a single linear coil is presented. By a synergistic combination of controlled radical polymerization, convergent dendrimer synthesis, and benzoeyclobutene (BCB) cross-linking chemistry, strategies for the preparation of a variety of nanoparticle-coil copolymers were developed. Atomic force microscopy (AFM) was used to confirm the formation of architecturally differentiated block copolymers and enabled visualization of individual nanoparticles and their linear chain components for unambiguous characterization of the nanoparticle-coil structures. This confirmed the synthesis of the targeted nanostructure and revealed the dramatic effect that changes in macromolecular architecture can have on the morphology and assembly of these hybrid nanoparticle systems.

  DOI：

  10.1021/ma047375f
• 作为产物：
  描述：

  4-(四氢吡喃基氧基甲基)苄氯 在 lithium aluminium tetrahydride 、 18-冠醚-6 、 四溴化碳 、 potassium carbonate 、 N,N-二异丙基乙胺 、 三苯基膦 、 potassium iodide 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 26.25h， 生成 (3,5-Bis-{3,5-bis-[4-(tetrahydro-pyran-2-yloxymethyl)-benzyloxy]-benzyloxy}-phenyl)-methanol
  参考文献：
  名称：

  Synthesis and Direct Visualization of Block Copolymers Composed of Different Macromolecular Architectures

  摘要：

  A novel approach toward the synthesis of block copolymers composed of architecturally different components, in this case, a nanoparticle covalently attached to a single linear coil is presented. By a synergistic combination of controlled radical polymerization, convergent dendrimer synthesis, and benzoeyclobutene (BCB) cross-linking chemistry, strategies for the preparation of a variety of nanoparticle-coil copolymers were developed. Atomic force microscopy (AFM) was used to confirm the formation of architecturally differentiated block copolymers and enabled visualization of individual nanoparticles and their linear chain components for unambiguous characterization of the nanoparticle-coil structures. This confirmed the synthesis of the targeted nanostructure and revealed the dramatic effect that changes in macromolecular architecture can have on the morphology and assembly of these hybrid nanoparticle systems.

  DOI：

  10.1021/ma047375f