(2S,3R,4S,5R,6R)-2-Ethyldisulfanyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol | 207908-00-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5R,6R)-2-Ethyldisulfanyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
• CAS: 207908-00-7
• 化学式: C₈H₁₆O₅S₂
• 分子量: 256.344
• InChiKey: BHSCDTBPPXVDSS-HNEXDWKRSA-N

物化性质

• 沸点：
  473.4±45.0 °C(Predicted)
• 密度：
  1.50±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.81
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.15
• 氢给体数：
  4.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  (2S,3R,4S,5R,6R)-2-Ethyldisulfanyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 、 以64%的产率得到(2S,3R,4S,5R,6R)-2-((2R,3R,4R,5R,6R)-4,5-Dihydroxy-2-hydroxymethyl-6-octyloxy-tetrahydro-pyran-3-ylsulfanyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Solid-Phase Synthesis of Thio-oligosaccharides

  摘要：

  No protecting groups are present in the highly reactive polymer-bound sugar 1-thiolates 1, which undergo reactions with sugar triflates 2 to give thio-oligosaccharides 3 in high yield. Tr=trityl=triphenylmethyl, Tf=trifluoromethylsulfonyl, Bz=benzoyl.

  DOI：

  10.1002/(sici)1521-3773(19990614)38:12<1782::aid-anie1782>3.0.co;2-1
• 作为产物：
  描述：

  2,3,4,6-四-O-乙酰基-1-硫代-BETA-D-吡喃半乳糖 在 sodium methylate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 0.08h， 生成 (2S,3R,4S,5R,6R)-2-Ethyldisulfanyl-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Solid-Phase Synthesis of Thio-oligosaccharides

  摘要：

  No protecting groups are present in the highly reactive polymer-bound sugar 1-thiolates 1, which undergo reactions with sugar triflates 2 to give thio-oligosaccharides 3 in high yield. Tr=trityl=triphenylmethyl, Tf=trifluoromethylsulfonyl, Bz=benzoyl.

  DOI：

  10.1002/(sici)1521-3773(19990614)38:12<1782::aid-anie1782>3.0.co;2-1