bis-(4-benzyloxyphenyl)methane | 51572-32-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis-(4-benzyloxyphenyl)methane
• 英文别名: bis-(4-benzyloxy-phenyl)-methane；Bis-(4-benzyloxy-phenyl)-methan；Bis-(p-benzyloxyphenyl)-methan；1-Phenylmethoxy-4-[(4-phenylmethoxyphenyl)methyl]benzene
• CAS: 51572-32-8
• 化学式: C₂₇H₂₄O₂
• 分子量: 380.486
• InChiKey: PMFSXPPQUDJTSL-UHFFFAOYSA-N

物化性质

• 沸点：
  540.2±40.0 °C(Predicted)
• 密度：
  1.124±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4,4'-二羟基二苯甲烷 生成 bis-(4-benzyloxyphenyl)methane
  参考文献：
  名称：

  Crystalline dihydroxy phenols

  摘要：

  公开号：

  US02464207A1
• 作为试剂：
  描述：

  sodium;hydride 、 4,4'-二羟基二苯甲烷 、 氯化苄 在 水 、 乙醚 、 magnesium sulfate 、 乙醇 、 bis-(4-benzyloxyphenyl)methane 、 silica gel 、 氯仿 、 二苄醚 、 异丙醚 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 17.0h， 生成 α-(p-Benzyloxyphenyl)-p-kresol
  参考文献：
  名称：

  Sulfuric acid esters of bis-(4-hydroxyphenyl)-methane

  摘要：

  双（4-羟基苯基）甲烷的硫酸酯及其药学上可接受的盐，例如，硫酸双（4-羟基苯基）甲烷钠二酯，在治疗脂质血症方面具有用途。

  公开号：

  US03932481A1

文献信息

• Organometallic SERMs (selective estrogen receptor modulators): Cobaltifens, the (cyclobutadiene)cobalt analogues of hydroxytamoxifen
  作者：Kirill Nikitin、Yannick Ortin、Helge Müller-Bunz、Marie-Aude Plamont、Gérard Jaouen、Anne Vessières、Michael J. McGlinchey

  DOI：10.1016/j.jorganchem.2009.11.003

  日期：2010.2

  The McMurry coupling of (tetraphenylcyclobutadiene)cobalt(cyclopentadienyl) ketones, (C4Ph4)Co[C5H4C(=O)R], where R = Me, 3a, or Et, 3b, with a range of substituted benzophenones furnished a series of cobaltifens, organometallic analogues of tamoxifen whereby a phenyl ring has been replaced by an organo-cobalt sandwich moiety. These systems of the general formula (eta(4)-C4Ph4)Co[eta(5)-C5H4C(R)=C(Ar)Ar'], where R = Me or Et, and Ar = Ar' = p-C6H4X where X is OH, 2a and 2b, OMe, 2c and 2d, OBn, 2e and 2f, or O(CH2)(2)NMe2, 12a and 12b, and where Ar = C6H4OH and Ar' = C6H4O(CH2)(2)NMe2, 2g and 2h, have been characterised by NMR spectroscopy and/or X-ray crystallography. The effect of 2a and 2b, 2g and 2h, and 12a and 12b on the growth of MCF-7 (hormone-dependent) and MDA-MB-231 (hormone-independent breast cancer cells) was studied. The dihydroxycobaltifens 2a and 2b exhibit a strong estrogenic effect on MCF-7 cells while the aminoalkyl-hydroxycobaltifens, 2g and 2h, were found to be only slightly cytotoxic on MDA-MB-231 cells (IC50 = 27.5 and 17 mu M); surprisingly, however, the bis-(dimethylaminoethoxy) cobaltifens, 12a and 12b were shown to be highly cytotoxic towards both cell lines (IC50 = 3.8 and 2.5 mu M). (C) 2009 Elsevier B.V. All rights reserved.
• IOVU, MIRCEA;ISPAS, FLOAREA, REV. CHIM., 38,(1987) N 5, 380-384
  作者：IOVU, MIRCEA、ISPAS, FLOAREA

  DOI：——

  日期：——
• VINYLBENZYL-ETHERIFIED-DOPO COMPOUND RESIN COMPOSITION AND PREPARATION AND APPLICATION THEREOF
  申请人：ELITE ELECTRONIC MATERIAL (ZHONG SHAN) CO., LTD.

  公开号：US20150166788A1

  公开（公告）日：2015-06-18

  The present invention belongs to the technical field of a resin having low dielectric properties, and presents a vinylbenzyl-etherified-DOPO compound resin composition and a preparation method and application thereof. The composition includes a vinylbenzyl-etherified-DOPO compound resin and a vinyl-terminated polyphenylene ether resin. The DOPO resin is vinylbenzyl etherified in the present invention, thus obtaining a vinylbenzyl-etherified-DOPO compound resin having low dielectric properties, and there are no hydroxyl group on itself, no hydroxyl function group will be generated during the cross-linking reaction; and the vinylbenzyl-etherified-DOPO compound resin contains phosphorus atoms, and has flame retardancy. The prepared vinylbenzyl-etherified-DOPO compound resin and the hydroxyl-free, low dielectric vinyl-terminated polyphenylene ether resin are combined in the present invention, thus obtaining a resin composition having low dielectric constant and low dielectric loss tangent, which can achieve excellent dielectric properties and flame retardancy when applying to the metal laminates and printed circuit boards.
• US3932481A
  申请人：——

  公开号：US3932481A

  公开（公告）日：1976-01-13
• US3931275A
  申请人：——

  公开号：US3931275A

  公开（公告）日：1976-01-06