2,3-dicyclopropyl-2,3-dimethylbutane

• 分子结构分类: 有机化合物 - 碳氢化合物 - 饱和烃
• 英文名称: 2,3-dicyclopropyl-2,3-dimethylbutane
• 英文别名: (3-Cyclopropyl-2,3-dimethylbutan-2-yl)cyclopropane
• 化学式: C₁₂H₂₂
• 分子量: 166.307
• InChiKey: YGNNMGXHUBICEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  环丙甲基酮 在 氯 、 一水合肼 作用下， 以 正己烷 为溶剂， 反应 27.0h， 生成 2,3-dicyclopropyl-2,3-dimethylbutane
  参考文献：
  名称：

  Clocking Tertiary Cyclopropylcarbinyl Radical Rearrangements¹

  摘要：

  Three independent methods have been employed to estimate the rate constant, k(1), for ring-opening of the 2-cyclopropyl-2-propyl radical, 1, at room temperature. These three estimates are based on chemical trapping of 1 and the ring-opened 4-methylpent-3-ene-1-yl radical by thiophenol (k(1) = (1.6(5) +/- 0.4(1)) x 10(7) M(-1) s(-1)), 9-azabicyclo[3.3.1]nonane-N-oxyl (k(1) = (1.7(6) +/- 0.3(4)) x 10(7) M(-1) s(-1)) and 2,2,6,6-tetramethylpiperidine-N-oxyl (k(1) = (2.1 +/- 0.4) x 10(7) M(-1) s(-1)) and absolute rate constants for nonrearranging radicals structurally related to 1. The mean value for k(1) ((1.8(4) +/- 0.4) x 10(7) M(-1) s(-1)) should be used when 1 is employed as a tertiary alkyl free radical clock at ambient temperatures.

  DOI：

  10.1021/jo961685h

文献信息

• Clocking Tertiary Cyclopropylcarbinyl Radical Rearrangements¹
  作者：Paul S. Engel、Shu-Lin He、J. T. Banks、K. U. Ingold、J. Lusztyk

  DOI：10.1021/jo961685h

  日期：1997.3.1

  Three independent methods have been employed to estimate the rate constant, k(1), for ring-opening of the 2-cyclopropyl-2-propyl radical, 1, at room temperature. These three estimates are based on chemical trapping of 1 and the ring-opened 4-methylpent-3-ene-1-yl radical by thiophenol (k(1) = (1.6(5) +/- 0.4(1)) x 10(7) M(-1) s(-1)), 9-azabicyclo[3.3.1]nonane-N-oxyl (k(1) = (1.7(6) +/- 0.3(4)) x 10(7) M(-1) s(-1)) and 2,2,6,6-tetramethylpiperidine-N-oxyl (k(1) = (2.1 +/- 0.4) x 10(7) M(-1) s(-1)) and absolute rate constants for nonrearranging radicals structurally related to 1. The mean value for k(1) ((1.8(4) +/- 0.4) x 10(7) M(-1) s(-1)) should be used when 1 is employed as a tertiary alkyl free radical clock at ambient temperatures.