3-nitrobenzothiazolo<3,2-a>quinolinium chloride | 82773-08-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-nitrobenzothiazolo<3,2-a>quinolinium chloride
• 英文别名: 3-nitrobenzothiazolo[3,2-a]quinolinium chloride；3-Nitrobenzothiazolo(3,2-a)quinolinium chloride；3-nitro-[1,3]benzothiazolo[3,2-a]quinolin-12-ium;chloride
• CAS: 82773-08-8
• 化学式: C₁₅H₉N₂O₂S*Cl
• 分子量: 316.768
• InChiKey: NQZNSKWXRMGQTR-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.71
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-氯-5-硝基苯甲醛 在 乙酸酐 作用下， 以 1,4-二氧六环 、 苯 为溶剂， 反应 29.0h， 生成 3-nitrobenzothiazolo<3,2-a>quinolinium chloride
  参考文献：
  名称：

  苯并噻唑并[3,2-a]喹啉鎓盐的合成及生物活性。

  摘要：

  DOI：

  10.1021/jm00353a020

文献信息

• [EN] ELECTROCHEMICAL AFFINITY SENSOR<br/>[FR] CAPTEUR D'AFFINITÉ ÉLECTROCHIMIQUE
  申请人：NEWSOUTH INNOVATIONS PTY LTD

  公开号：WO2013029114A1

  公开（公告）日：2013-03-07

  Disclosed herein is an electrochemical sensor comprising an electrode having a protective layer; conductive nanoparticles bound to the protective layer; a redox active species bound to the conductive nanoparticles; and a binding moiety capable of associating with an analyte, the binding moiety being associated with the redox active species bound to the conductive nanoparticles. Association of a binding moiety with the analyte modulates the electrochemistry of the redox active species.
• [EN] ELECTROCHEMICAL COMPETITION SENSOR<br/>[FR] CAPTEUR DE COMPÉTITION ÉLECTROCHIMIQUE
  申请人：NEWSOUTH INNOVATIONS PTY LTD

  公开号：WO2013029115A1

  公开（公告）日：2013-03-07

  Disclosed herein is a method for detecting the presence of an analyte in a sample. The method comprises the steps of: adding to the sample an antibody of the analyte; exposing to the sample a binding moiety capable of becoming associated with the antibody of the analyte, the binding moiety being associated with a redox active species that is bound to an electrode and electrochemically accessible to the electrode; and taking amperometric electrochemical measurements which indicate whether the electrochemistry of the redox active species has been modulated by the binding moiety associating with the antibody of the analyte. The analyte may, for example, be glycosylated haemoglobin, HbA1c.
• Synthesis and biological activity of benzothiazolo- and benzoxazolo[3,2-a]quinolinium salts
  作者：Osvaldo Cox、Henry Jackson、Vanessa A. Vargas、Adriana Baez、Julio I. Colon、Blanca C. Gonzalez、Marino De Leon

  DOI：10.1021/jm00353a020

  日期：1982.11