申请人:Eli Lilly and Company
公开号:US05552441A1
公开(公告)日:1996-09-03
This invention provides certain 1,2,4,5 substituted benzene derivatives containing "acid" substituents derived from cyclic or heterocyclic moieties. These unique compounds are leukotriene B.sub.4 antagonists and formulations of these derivatives, and a method of using these derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.
本发明提供了一些含有“酸”取代基的1,2,4,5取代苯衍生物,这些取代基源于环状或杂环状基团。这些独特的化合物是白三烯B.sub.4拮抗剂,这些衍生物的配方以及使用这些衍生物治疗白三烯过度释放引起的症状的方法。