1-tert.-Butyloxy-2-methyl-butan | 90724-68-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-tert.-Butyloxy-2-methyl-butan
• 英文别名: 2-Methylbutyl-tert.-butyl-aether；1-tert-butoxy-2-methyl-butane；2-Methyl-1-[(2-methylpropan-2-yl)oxy]butane
• CAS: 90724-68-8
• 化学式: C₉H₂₀O
• 分子量: 144.257
• InChiKey: LTSQRKMUKSTWKM-UHFFFAOYSA-N

物化性质

• 沸点：
  139.9±8.0 °C(Predicted)
• 密度：
  0.784±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-苯磺酰氧基-2-甲基丁烷 在 potassium tert-butylate 作用下， 以 二甲基亚砜 为溶剂， 反应 0.5h， 生成 1-tert.-Butyloxy-2-methyl-butan 、 2-甲基-丁烯
  参考文献：
  名称：

  The Reaction of Primary and Secondary Alkylaryl and Alkyl Sulfonates with Potassium t-Butoxide in Dimethyl Sulfoxide¹

  摘要：

  DOI：

  10.1021/jo01026a055

文献信息

• Benzene, Pyridine, and Pyridazine Derivatives
  申请人：Huang Kenneth He

  公开号：US20080096887A1

  公开（公告）日：2008-04-24

  Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , n, Q 1 , Q 2 , Q 3 , Y, and X 1 -X 4 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.

  本发明公开了式I的化合物和药学上可接受的盐，其中R1、R2、R3、R4、R5、R6、R7、n、Q1、Q2、Q3、Y和X1-X4的定义如本文所述。式I的化合物可用于治疗与细胞增殖有关的疾病和/或疾病，例如癌症、炎症、关节炎、血管生成或类似疾病。本发明还公开了包含本发明化合物的制药组合物和使用这些化合物治疗上述疾病的方法。
• BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES
  申请人：Huang Kenneth He

  公开号：US20110183977A1

  公开（公告）日：2011-07-28

  Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , n, Q 1 , Q 2 , Q 3 , Y, and X 1 -X 4 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.

  本发明揭示了公式I的化合物和药学上可接受的盐，其中R1、R2、R3、R4、R5、R6、R7、n、Q1、Q2、Q3、Y和X1-X4的定义如本文所述。公式I的化合物在治疗与细胞增殖相关的疾病和/或病况，例如癌症、炎症、关节炎、血管生成等方面非常有用。本发明还揭示了包含本发明化合物的药物组合物以及使用这些化合物治疗上述病况的方法。
• COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：KANNA Shinichi

  公开号：US20110217636A1

  公开（公告）日：2011-09-08

  The present invention provides a colored curable composition including a phthalocyanine pigment, a dioxazine pigment, a dye, a polymerization initiator, a polymerizable compound and a solvent; and a colored curable composition including a phthalocyanine pigment, a dye multimer having a polymerizable group and a group derived from a dipyrromethene dye, a polymerization initiator, a polymerizable compound and a solvent.

  本发明提供了一种彩色可固化组合物，包括酞菁颜料、二氧化锰颜料、染料、聚合引发剂、可聚合化合物和溶剂；以及一种彩色可固化组合物，包括酞菁颜料、具有可聚合基团和源自二吡咯甲烷染料的染料多聚物、聚合引发剂、可聚合化合物和溶剂。
• BISPHENOL COMPOUNDS AND METHODS FOR THEIR USE
  申请人：Andersen Raymond John

  公开号：US20140248263A1

  公开（公告）日：2014-09-04

  Compounds having a structure of Formula I: wherein G, a, Q, L 2 , R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as defined herein are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  提供具有公式I结构的化合物，其中G，a，Q，L2，R1，R2，R3，R4，R5和R6的定义如本文所述。提供了这种化合物用于治疗各种适应症，包括前列腺癌以及涉及这种化合物的治疗方法。
• BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS
  申请人：Sadar Marianne D.

  公开号：US20130131167A1

  公开（公告）日：2013-05-23

  This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.