1-(4-bromophenyl)decan-1-one | 134443-99-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(4-bromophenyl)decan-1-one
• 英文别名: 1-(4-Bromo-phenyl)-decan-1-one
• CAS: 134443-99-5
• 化学式: C₁₆H₂₃BrO
• 分子量: 311.262
• InChiKey: AFYLBBNAPMAFME-UHFFFAOYSA-N

物化性质

• 沸点：
  381.3±25.0 °C(Predicted)
• 密度：
  1.156±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(4-bromophenyl)decan-1-one 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 14.0h， 生成 1-Cyanophenyl-4-decan-1'-one ethyleneketal
  参考文献：
  名称：

  Neubert, M. E.; Sharma, R. B.; Citano, C., Molecular Crystals and Liquid Crystals (1969-1991), 1991, vol. 196, p. 145 - 155

  摘要：

  DOI：
• 作为产物：
  描述：

  正癸酸 在 三氯化铝 、 草酰氯 作用下， 生成 1-(4-bromophenyl)decan-1-one
  参考文献：
  名称：

  Room-Temperature Discotic Nematic Liquid Crystals

  摘要：

  The use of discotic nematic liquid crystals instead of calamitic nematic liquid crystals to improve the viewing angle of a liquid crystal display device has recently been reported. Compared to the large number of calamitic molecules showing nematic phase at room temperature, the number of disk-shaped molecules showing subambient discotic nematic phase N-D are rare. In this paper we present the design, synthesis, mesomorphic behaviour and structure-property relationship of discotic nematic liquid crystals based on benzene multiyne core.

  DOI：

  10.1080/15421400390213573

文献信息

• Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection
  作者：Rosalina Wisastra、Petra A.M. Kok、Nikolaos Eleftheriadis、Matthew P. Baumgartner、Carlos J. Camacho、Hidde J. Haisma、Frank J. Dekker

  DOI：10.1016/j.bmc.2013.10.015

  日期：2013.12

  human 5-LOX. This compound showed both non-competitive activation towards the human 5-LOX activator adenosine triphosphate (ATP) and non-essential mixed type activation against the substrate linoleic acid, while having no effect on the conversion of the substrate arachidonic acid. The kinetic analysis demonstrated a non-essential activation of the linoleic acid conversion with a KA of 8.65 μM, αKA of

  脂肪氧化酶 (LOX) 和环氧合酶 (COX) 将多不饱和脂肪酸代谢为炎症信号分子。调节这些酶的活性可能为治疗炎性疾病提供新方法。在这项研究中，我们筛选了新型漆树酸衍生物作为人类 5-LOX 和 COX-2 活性的调节剂。有趣的是，一种新型的水杨酸衍生物23a被鉴定为人 5-LOX 的一种令人惊讶的有效激活剂。该化合物显示出对人 5-LOX 激活剂三磷酸腺苷 (ATP) 的非竞争性激活和对底物亚油酸的非必需混合型激活，同时对底物花生四烯酸的转化没有影响。动力学分析证明了亚油酸转化的非必要激活，其K A为 8.65 μM，αK A为 0.38 μM，β值为 1.76。同样有趣的是，一个可比较的导数23d显示出对亚油酸转化的混合型抑制作用。这些观察结果表明人 5-LOX 中存在不同于 ATP 结合位点的变构结合位点。与花生四烯酸相比，23a和23d对亚油酸转化的激活和抑制行为通过对接研究合理化
• Solution Processable Symmetric 4-Alkylethynylbenzene End-Capped Anthracene Derivatives
  作者：Sang-Hun Jang、Hyun-Jin Kim、Min-Ji Hwang、Eun-Bin Jeong、Hui-Jun Yun、Dong-Hoon Lee、Yun-Hi Kim、Chan-Eon Park、Yong-Jin Yoon、Soon-Ki Kwon、Sang-Gyeong Lee

  DOI：10.5012/bkcs.2012.33.2.541

  日期：2012.2.20

  New candidates composed of anthracene and 4-alkylethynylbenzene end-capped oligomers for OTFTs were synthesized under Sonogashira coupling reaction conditions. All oligomers were characterized by FT-IR, mass, UV-visible, and PL emission spectrum analyses, cyclic voltammetry (CV), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), $^1H$-NMR, and $^13}C$-NMR. Investigation of their physical properties showed that the oligomers had high oxidation potential and thermal stability. Thin films of DHPEAnt and DDPEAnt were characterized by spin coating them onto Si/$SiO_2$ to fabricate top-contact OTFTs. The devices prepared using DHPEAnt and DDPEAnt showed hole field-effect mobilities of $4.0\times}10^-3}cm^2$/Vs and $2.0\times}10^-3}cm^2$/Vs, respectively, for solution-processed OTFTs.

  在 Sonogashira 偶联反应条件下合成了由蒽和 4-烷基乙炔基苯端帽低聚物组成的新的 OTFT 候选材料。通过傅立叶变换红外光谱、质量、紫外可见光和聚光发射光谱分析、循环伏安法（CV）、差示扫描量热法（DSC）、热重分析（TGA）、$^1H$-NMR 和 $^13}C$-NMR，对所有低聚物进行了表征。对其物理性质的研究表明，这些低聚物具有较高的氧化电位和热稳定性。通过在硅/$SiO_2$上旋涂 DHPEAnt 和 DDPEAnt 薄膜，制备了顶接触 OTFT。使用DHPEAnt和DDPEAnt制备的器件显示，溶液加工的OTFT的空穴场效应迁移率分别为$4.0\times}10^-3}cm^^2$/Vs和$2.0\times}10^-3}cm^^2$/Vs。
• Synthesis of new iridium complexes and their electrophosphorescent properties in polymer light-emitting diodes
  作者：Weiguo Zhu、Chuanzhen Liu、Lijun Su、Wei Yang、Ming Yuan、Yong Cao

  DOI：10.1039/b205310a

  日期：2003.12.10

  Several new iridium complexes with p-substituted 2-phenylpyridine (R-PPy) ligands have been synthesized and characterized. The complexes were incorporated into phosphorescent polymer light-emitting devices using soluble poly[1,4-bis(6′-cyano-6′-methylheptyloxy)phenylene] (CNPPP) as the host and the resultant materials compared with Ir(PPy)3-doped devices. Green electrophosphorescence was observed, with peak emission at about 495 and 515 nm. Among the devices fabricated, highly efficient polymer light-emitting diodes were obtained with CNPPP doped with fac-tris[2-(4-tert-butylphenyl)pyridinato]iridium. An external quantum efficiency of 4.4% (photoluminescence/electroluminescence) and a luminous efficiency of 10 cd A−1 were obtained at 120 cd m−2. These values remain at 4.2% and 10 cd A−1, respectively, at 2500 cd m−2. The improvement is attributed to improved interaction between the guest and host, and to better and more complete energy transfer from the host singlet to the guest triplet state. These results demonstrate that efficient electrophosphorescence is not limited to small molecule organic light-emitting diodes, it can also be achieved in devices made with polymer hosts.

  几种带有对位取代的 2-苯基吡啶 (R-PPy) 配体的新型铱配合物已被合成并表征。以可溶性聚[1,4-双(6'-氰基-6'-甲基庚氧基)亚苯基](CNPPP)为主体，将配合物引入磷光聚合物发光器件中，并将所得材料与Ir(PPy)3进行比较-掺杂器件。观察到绿色电致磷光，峰值发射位于约 495 和 515 nm 处。在所制造的器件中，利用掺杂fac-三[2-(4-叔丁基苯基)吡啶]铱的CNPPP获得了高效聚合物发光二极管。在120 cd m−2 下获得了4.4% 的外量子效率（光致发光/电致发光）和10 cd A−1 的发光效率。在 2500 cd m−2 时，这些值分别保持在 4.2% 和 10 cd A−1。这种改进归因于客体和主体之间相互作用的改善，以及从主体单线态到客体三线态更好、更完整的能量转移。这些结果表明，高效的电致磷光不仅限于小分子有机发光二极管，它也可以在由聚合物主体制成的器件中实现。
• Acridine-Based SNS–Ruthenium Pincer Complex-Catalyzed Borrowing Hydrogen-Mediated C–C Alkylation Reaction: Application to the Guerbet Reaction
  作者：Dipankar Srimani、Nandita Biswas、Rahul Sharma、Bitan Sardar

  DOI：10.1055/a-1874-2406

  日期：2023.4

  SNS-based ruthenium pincer catalysts were applied in a Guerbet condensation reaction of primary alcohols to give β-alkylated dimeric alcohols in good yields. The ability of these complexes to convert ethanol into butanol was also investigated. The work was then extended toward the C-alkylation of secondary alcohols with primary alcohols to give α-alkylated ketones. Several control experiments showed

  将基于 SNS 的钌钳形催化剂应用于伯醇的 Guerbet 缩合反应，以良好的收率得到 β-烷基化二聚醇。还研究了这些配合物将乙醇转化为丁醇的能力。然后将工作扩展到仲醇与伯醇的 C-烷基化以得到 α-烷基化酮。几个对照实验表明，在协议中涉及借氢。
• Synthesis and Electronic Properties of Semiconducting Polymers Containing Benzodithiophene with Alkyl Phenylethynyl Substituents
  作者：Prakash Sista、Hien Nguyen、John W. Murphy、Jing Hao、Daniel K. Dei、Kumaranand Palaniappan、John Servello、Ruvini S. Kularatne、Bruce E. Gnade、Bofei Xue、Paul C. Dastoor、Michael C. Biewer、Mihaela C. Stefan

  DOI：10.1021/ma101709h

  日期：2010.10.12

  Semiconducting polymers containing benzodithiophene with decyl phenylethynyl and hexadecyl phenylethynyl substituents have been synthesized by Sidle coupling polymerization. The optoelectronic properties of the synthesized polymers have been investigated. The synthesized polymers were tested in bulk heterojunction solar cells.