5-(2'-chloro-4'-trifluoromethylphenoxy)-3-methyl-3-hydroxyphthalide | 99199-40-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-(2'-chloro-4'-trifluoromethylphenoxy)-3-methyl-3-hydroxyphthalide
• 英文别名: 5-(2-chloro-4-trifluoromethylphenoxy)-3-hydroxy-3-methylphthalide；5-(2-chloro-4-trifluoromethylphenoxy)-3-methyl-3-hydroxyphthalide；5-[2-chloro-4-(trifluoromethyl)phenoxy]-3-hydroxy-3-methyl-2-benzofuran-1-one
• CAS: 99199-40-3
• 化学式: C₁₆H₁₀ClF₃O₄
• 分子量: 358.701
• InChiKey: WSYHUDHORSPIOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  溴乙烷 、 5-(2'-chloro-4'-trifluoromethylphenoxy)-3-methyl-3-hydroxyphthalide 在 盐酸 、 magnesium 作用下， 以 乙醚 为溶剂， 生成 5-(2-chloro-4-trifluoromethylphenoxy)-3-ethyl-3-methyl-phthalide
  参考文献：
  名称：

  Process for preparing diphenyl ethers

  摘要：

  Diphenyl ether derivatives of formula II ##STR1## wherein R.sub.1 represents a hydrogen or halogen atom or an alkyl or haloalkyl group, R.sub.2 and R.sub.3, which may be the same or different, each independently represents a hydrogen or halogen atom, or an alkyl, haloalkyl, nitro or cyano group, and R.sub.6 represents a hydrogen atom or an alkyl group, useful as intermediates in the preparation of diphenyl ether herbicides, are prepared by treating a compound of formula III ##STR2## where R.sub.1, R.sub.2 and R.sub.3 are as defined above with a dicarboxylic acid of formula R.sub.6 --CH(COOH).sub.2, where R.sub.6 is as defined above, in the presence of an organic base.

  公开号：

  US05183907A1
• 作为产物：
  描述：

  5-(2-chloro-4-trifluoromethylphenoxy)-phthalic anhydride 在 丙二酸 、 三乙胺 作用下， 以 水 、 乙酸乙酯 为溶剂， 以154 g (43%)的产率得到5-(2'-chloro-4'-trifluoromethylphenoxy)-3-methyl-3-hydroxyphthalide
  参考文献：
  名称：

  Process for preparing diphenyl ethers

  摘要：

  Diphenyl ether derivatives of formula II ##STR1## wherein R.sub.1 represents a hydrogen or halogen atom or an alkyl or haloalkyl group, R.sub.2 and R.sub.3, which may be the same or different, each independently represents a hydrogen or halogen atom, or an alkyl, haloalkyl, nitro or cyano group, and R.sub.6 represents a hydrogen atom or an alkyl group, useful as intermediates in the preparation of diphenyl ether herbicides, are prepared by treating a compound of formula III ##STR2## where R.sub.1, R.sub.2 and R.sub.3 are as defined above with a dicarboxylic acid of formula R.sub.6 --CH(COOH).sub.2, where R.sub.6 is as defined above, in the presence of an organic base.

  公开号：

  US05183907A1

文献信息

• Diphenyl ether herbicides
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0306095A1

  公开（公告）日：1989-03-08

  Phenoxy phthalide derivatives having the general formula II: wherein R₁ represents a hydrogen or halogen atom or an alkyl or haloalkyl group; R₂ and R₃, which may be the same or different, each independently represents a hydrogen or halogen atom or an alkyl, haloalkyl, nitro or cyano group; R₄ represents a saturated alkyl group; R₅ represents an unsaturated alkyl group; and X represents an oxygen or sulphur atom, are useful as herbicides.

  具有通式 II 的苯氧基邻苯二甲酸酯衍生物： 其中 R₁ 代表氢原子或卤素原子或烷基或卤代烷基；R₂ 和 R₃ 可以相同或不同，各自独立地代表氢原子或卤素原子或烷基、卤代烷基、硝基或氰基；R₄ 代表饱和烷基；R₅ 代表不饱和烷基；X 代表氧原子或硫原子，可用作除草剂。
• JPH01106877A
  申请人：——

  公开号：JPH01106877A

  公开（公告）日：1989-04-24
• US4927945A
  申请人：——

  公开号：US4927945A

  公开（公告）日：1990-05-22
• US5073192A
  申请人：——

  公开号：US5073192A

  公开（公告）日：1991-12-17
• US5183907A
  申请人：——

  公开号：US5183907A

  公开（公告）日：1993-02-02