Microwave-Assisted Synthesis of 3,5-Disubstituted Thiohydantoins Using Functional Ionic Liquid as Soluble Support
摘要:
A new approach for the syntheses of 3,5-disubstituted thiohydantoins was described using functionalized ionic liquid as soluble support. The products were obtained in good yields and purities after cyclization-cleavage from the ionic-liquid-supported under microwave irradiation, the ionic-liquid-supported species can there be purified from the reaction mixture by simple washing, and no chromatographic purification were needed during the synthesis.
Applicability of a Modified Edman Procedure for Measurement of Protein Adducts: Mechanisms of Formation and Degradation of Phenylthiohydantoins
作者:Per Rydberg、Björn Lüning、Carl Axel Wachtmeister、Lars Eriksson、Margareta Törnqvist
DOI:10.1021/tx000247+
日期:2002.4.1
and oxidative processes give rise to degradation products. The PTH derivatives of N-alkylvaline are less apt to undergo such reactions than are the corresponding derivatives of unsubstituted valine. We conclude that the presence of an N-substituent exerts a greater influence on the cyclization process than the structure of the amino acid or of the Edman reagent. For adducts of different structures, the
Among the Missing: Content on Lesbian and Gay People in Social Work Journals
作者:R. Van Voorhis、M. Wagner
DOI:10.1093/sw/47.4.345
日期:2002.10.1
Lesbian and gay issues are barely visible in the social work literature. This study examined the content of articles on homosexuality that were published in four major social work journals between 1988 and 1997. Articles were coded according to their focus on either HIV/AIDS and the gay community or other issues pertaining to lesbians and gay men. Articles were also coded as client focused, worker focused, or macro focused. Two-thirds of the 77 articles published on homosexuality focused on HIV/AIDS. Most articles reflected a problem-oriented view of gay and lesbian people; few addressed heterosexism or environmental interventions. More literature is needed that focuses on strengths, heterosexist conditions, and social justice for lesbian and gay people.
An Efficient Method for Synthesis of Thiohydantoins with a-Amino Esters Under Microwave Irradiation
作者:Yanmei Zhao、Zhouyu Wang、Zhenju Jiang、Hualin Feng、Li Liu、Ju Wang
DOI:10.14233/ajchem.2014.16119
日期:——
An efficient and simple way for synthesis of thiohydantoins is reported. In the absence of any additional catalysts, a series of thiohydantoins were synthesized with amino esters and isothiocyanates in aqueous medium under microwave irradiation. Excellent isolated yields (up to 98 %) were obtained under mild conditions.
Method for analyzing adducts in a fluid and/or a solid material suspected of containing the adducts by bringing the material in contact with an isothiocyanate reagent containing a fluorescent. The reagent do not have the isothiocyanate group directly bound to an unsubstituted phenyl or pentafluorophenyl group. A method for manufacturing a standard material for use in the analyzing method, a standard material obtainable by this manufacturing method. Compounds suitable for use as standard material and use of the standard material, and a container for analyzing the adducts are also disclosed. A method for analyzing hazardous substances, a kit including standard material or a compound set out above, an apparatus for performing the analyzing method, and a computer program stored on a data carrier for performing the analyzing method or the manufacturing method are also disclosed.