methyl 1-octyl sulphite

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 1-octyl sulphite
• 英文别名: Methyl octyl sulfite；methyl octyl sulfite
• 化学式: C₉H₂₀O₃S
• 分子量: 208.322
• InChiKey: GPDRAPIHQBHGPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  13
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  54.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  methyl 1-octyl sulphite 在 aluminum oxide 作用下， 生成 1-甲氧基-辛烷
  参考文献：
  名称：

  Dimethyl sulfite a potential agent for methylation

  摘要：

  The synthesis of methylated ether compounds is an important challenge. A pathway for the synthesis of methyl ethers was investigated using dimethyl sulfite (DMSi). Methylation of 1-octanol was carried out in liquid phase upon different heterogeneous organic and inorganic catalysts at 130 degrees C. Aluminium oxide gave the best result with high conversion and moderate selectivity for methyl 1-octyl ether. Reactions in gas phase at higher temperatures (200 degrees C) were also performed. Methyl 1-octyl ether was obtained in a very high level of selectivity up to 98%. Primary and secondary ethers from unsymmetrical alkyl methyl sulfite were also performed by SO2 extrusion. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.09.075
• 作为产物：
  描述：

  辛醇 、 亚硫酸二甲酯 在 copper dichloride 作用下， 反应 68.0h， 以38%的产率得到methyl 1-octyl sulphite
  参考文献：
  名称：

  Dimethyl sulfite a potential agent for methylation

  摘要：

  The synthesis of methylated ether compounds is an important challenge. A pathway for the synthesis of methyl ethers was investigated using dimethyl sulfite (DMSi). Methylation of 1-octanol was carried out in liquid phase upon different heterogeneous organic and inorganic catalysts at 130 degrees C. Aluminium oxide gave the best result with high conversion and moderate selectivity for methyl 1-octyl ether. Reactions in gas phase at higher temperatures (200 degrees C) were also performed. Methyl 1-octyl ether was obtained in a very high level of selectivity up to 98%. Primary and secondary ethers from unsymmetrical alkyl methyl sulfite were also performed by SO2 extrusion. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.09.075

文献信息

• Process for the Preparation of Onium Alkylsulfonates
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20080221334A1

  公开（公告）日：2008-09-11

  The invention relates to a process for the preparation of onium alkylsulfonates by reaction of an onium halide or carboxylate with a symmetrically substituted dialkyl sulfite or with an asymmetrically substituted dialkyl sulfite at temperatures of 50 to 170° C.

  该发明涉及一种通过在50至170°C温度下将一个铵盐卤化物或羧酸盐与对称取代的二烷基亚磺酸酯或不对称取代的二烷基亚磺酸酯反应制备亚磺酸铵盐的方法。
• Process for the Preparation of Onium Alkylsulfites
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20080227987A1

  公开（公告）日：2008-09-18

  The invention relates to a process for the preparation of onium alkylsulfites by reaction of an onium halide or carboxylate with a symmetrically substituted dialkyl sulfite or with an asymmetrically substituted dialkyl sulfite at temperatures of 0 to 70° C.

  该发明涉及一种通过在0至70°C温度下，将一个铵盐卤化物或羧酸盐与对称取代的二烷基亚磺酸酯或非对称取代的二烷基亚磺酸酯反应制备亚磺酸铵化合物的方法。
• [DE] VERFAHREN ZUR HERSTELLUNG VON ONIUM-ALKYLSULFONATEN<br/>[EN] ONIUM-ALKYLSULFONATE PRODUCTION METHOD<br/>[FR] PROCEDE DE PRODUCTION D'ALKYLSULFONATES D'ONIUM
  申请人：MERCK PATENT GMBH

  公开号：WO2007006387A2

  公开（公告）日：2007-01-18

  (DE) Die Erfindung betrifft ein Verfahren zur Herstellung von Onium-Alkylsulfonaten durch Umsetzung eines Onium-Halogenids oder -Carboxylats mit einem symmetrisch substituierten Dialkylsulfit oder mit einem unsymmetrisch substituierten Dialkylsulfit bei Temperaturen von 50 bis 170°C.(EN) The invention relates to a method for producing onium-alkylsulfonates by reacting an onium halogenide or carboxylate with a symmetrically substituted dialkyl sulphite or with a asymmetrically substituted dialkyl sulphite at temperatures ranging from 50 to 170 °C.(FR) L'invention concerne un procédé de production d'alkylsulfonates d'onium par réaction d'un halogénure ou d'un carboxylate d'onium avec un sulfite de dialkyle substitué de façon symétrique ou avec un sulfite de dialkyle substitué de façon asymétrique à des températures comprises entre 50 et 170 °C.

  该发明涉及一种通过将含卤素或含碳酸根的对硝基化合物与对称二甲基硫醇、对称或不对称二甲基硫醇在50至170度之间反应从而制备对硝基甲基硫醇的方法。
• VERFAHREN ZUR HERSTELLUNG VON ONIUM-ALKYLSULFONATEN
  申请人：Merck Patent GmbH

  公开号：EP1902004A2

  公开（公告）日：2008-03-26
• VERFAHREN ZUR HERSTELLUNG VON ONIUM-ALKYLSULFITEN
  申请人：Merck Patent GmbH

  公开号：EP1902035A1

  公开（公告）日：2008-03-26