甲基二异戊基甲醇 | 64029-94-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 甲基二异戊基甲醇
• 英文名称: 2,5,8-Trimethyl-nonan-5-ol
• 英文别名: methyl-diisopentyl-carbinol；ε-Oxy-β.ε.λ-trimethyl-nonan；Methyl-diisoamyl-carbinol；2,5,8-trimethylnonan-5-ol
• CAS: 64029-94-3
• 化学式: C₁₂H₂₆O
• 分子量: 186.338
• InChiKey: GPXKYGMZPRGDTK-UHFFFAOYSA-N

物化性质

• 沸点：
  100-101 °C(Press: 9 Torr)
• 密度：
  0.8289 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  甲基二异戊基甲醇 在 盐酸 作用下， 生成 5-chloro-2,5,8-trimethyl-nonane
  参考文献：
  名称：

  Halse, Journal fur praktische Chemie (Leipzig 1954), 1914, vol. <2>89, p. 452

  摘要：

  DOI：
• 作为产物：
  描述：

  乙酸甲酯 、 magnesium,2-methylbutane,bromide 生成 甲基二异戊基甲醇
  参考文献：
  名称：

  Grignard, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901, vol. 132, p. 338

  摘要：

  DOI：

文献信息

• Grignard, Chemisches Zentralblatt, 1901, vol. 72, # II, p. 624
  作者：Grignard

  DOI：——

  日期：——
• Grignard, Annales de Chimie (Cachan, France), 1901, vol. <7> 24, p. 468
  作者：Grignard

  DOI：——

  日期：——
• Utilizing Propensity Scores to Estimate Causal Treatment Effects with Censored Time-Lagged Data
  作者：Kevin J. Anstrom、Anastasios A. Tsiatis

  DOI：10.1111/j.0006-341x.2001.01207.x

  日期：2001.12

  Observational studies frequently are conducted to compare long-term effects of treatments. Without randomization, patients receiving one treatment are not guaranteed to be prognostically comparable to those receiving another treatment. Furthermore, the response of interest may be right-censored because of incomplete follow-up. Statistical methods that do not account for censoring and confounding may lead to biased estimates. This article presents a method for estimating treatment effects in nonrandomized studies with right-censored responses. We review the assumptions required to estimate average causal effects and derive an estimator for comparing two treatments by applying inverse weights to the complete cases. The weights are determined according to the estimated probability of receiving treatment conditional on covariates and the estimated treatment-specific censoring distribution. By utilizing martingale representations, the estimator is shown to be asymptotically normal and an estimator for the asymptotic variance is derived. Simulation results are presented to evaluate the properties of the estimator. These methods axe applied to an observational data set of acute coronary syndrome patients from Duke University Medical Center to estimate the effect of a treatment strategy on the mean 5-year medical cost.
• HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP2097387B1

  公开（公告）日：2016-05-04
• Grignard, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901, vol. 132, p. 338
  作者：Grignard

  DOI：——

  日期：——