2-苯基苯并三唑-5-胺 | 21819-66-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 2-苯基苯并三唑-5-胺
• 英文名称: 2-phenyl-2H-benzo[d][1,2,3]triazol-5-amine
• 英文别名: 5-amino-2-phenyl-1,2,3-benzotriazole；2-phenyl-5-aminobenzotriazole；5-amino-2-phenylbenzotriazole；2-phenyl-2H-benzo[1,2,3]triazol-5-ylamine；2-phenyl-2H-benzotriazol-5-ylamine；2-Phenyl-2H-benzotriazol-5-ylamin；2-Phenyl-2H-benzotriazol-5-ylamine；2-phenylbenzotriazol-5-amine
• CAS: 21819-66-9
• 化学式: C₁₂H₁₀N₄
• mdl: MFCD00179563
• 分子量: 210.238
• InChiKey: NIOQXFRLZIIVCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56.7
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  2-苯基苯并三唑-5-胺 在 盐酸 、 sodium nitrite 、 potassium iodide 作用下， 以 水 为溶剂， 生成 2-phenyl-5-iodo-1,2,3-benzotriazole
  参考文献：
  名称：

  2-Phenyl-1,2,3-benzotriazole Ir(III) complexes with additional donor fragment for single-layer PhOLED devices

  摘要：

  Phosphorescent bis-cyclometallated iridium (III) complexes based on 2-phenyl-1,2,3-benzotriazole with additional donoric diphenylamine or carbazole moieties were synthesized, studied and tested as phosphorescent materials in the single-layer phosphorescent organic light emitting diodes. These single-layer devices were fabricated employing a simple technological approach, based upon the simultaneous vacuum deposition from one crucible of host material and the corresponding phosphorescent 1,2,3-triazole-based iridium complexes. Red and orange electrophosphorescent single-layer devices with current efficiencies of 5.3 cd/A and 6.8 cd/A respectively are reported. Results of the impedance spectroscopy suggest that the proposed method of formation of the working layer provides homogeneous distribution of molecular guest in the matrix of host. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.08.012
• 作为产物：
  描述：

  碱性橙 2 在 ammonium hydroxide 、 copper(ll) sulfate pentahydrate 作用下， 以 乙醇 、 水 为溶剂， 反应 4.0h， 以77%的产率得到2-苯基苯并三唑-5-胺
  参考文献：
  名称：

  Multifunctional red phosphorescent bis-cyclometallated iridium complexes based on 2-phenyl-1,2,3-benzotriazole ligand and carbazolyl moieties

  摘要：

  Multifunctional phosphorescent bis-cyclometallated iridium(III) complexes based on the 2-phenyl-1,2,3-benzotriazole moiety and bearing branched hole-transporting carbazole fragments were synthesized. The isolated compounds were found to be amorphous and expressed very good solubility. Introduction of flexible aliphatic chains of various lengths into the iridium complexes enabled manipulation of their glass transition temperature. The iridium complexes exhibited red phosphorescence emission at 650 nm with the lifetime of 5.7 mu s and phosphorescence quantum yields of 0.22 and 0.17 in solution and solid state, respectively, at room temperature. The shielding effect of the carbazolyl moieties on the concentration quenching of phosphorescence of the iridium centers was found to result in the increased excited state lifetime and quantum yield due to the suppressed exciton migration. Non-optimized OLED devices, based on the phosphorescent bis-cyclometallated iridium(III) complex without host material were fabricated and their electroluminescence properties were evaluated. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.01.026

文献信息

• [EN] ELECTROLUMINESCENT DEVICE<br/>[FR] DISPOSITIF ELECTROLUMINESCENT
  申请人：CIBA SC HOLDING AG

  公开号：WO2003105538A1

  公开（公告）日：2003-12-18

  Disclosed are electroluminescent devices that comprise organic layers that contain certain 2H-benzotriazole compounds. The 2H-benzotriazole compounds of blue-emitting, durable, organo-electrouminescent layers. The electroluminescent devices may be employed for full color display panels in for example mobile phones, televisions and personal computer screens.

  揭示了包含特定2H-苯并三唑化合物的有机层的电致发光器件。这些2H-苯并三唑化合物用于蓝光发射、耐久的有机电致发光层。这些电致发光器件可用于移动电话、电视和个人电脑屏幕等全彩显示面板。
• TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY
  申请人：Wynne Graham Michael

  公开号：US20100048660A1

  公开（公告）日：2010-02-25

  There are disclosed compound of Formula (I) or (II) wherein A 1 , A 2 , A 3 , A 4 and A 5 , which may be the same or different, represent N or CR 1 , R 9 represents -L-R 3 , in which L is a single bond or a linker group and R 3 represents hydrogen or a substituent and in addition, when an adjacent pair of A 1 -A 4 each represent CR 1 , then the adjacent carbon atoms, together with their substituents may form a ring B, when A 5 represents CR 1 , then A 5 and N—R 9 , together with their substituents may form a ring C, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the therapeutic and/or prophylactic treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia.

  公开了化合物的式子（I）或（II），其中A1、A2、A3、A4和A5，可以相同也可以不同，代表N或CR1，R9代表-L-R3，其中L是单键或连接基团，R3代表氢或取代基团，此外，当相邻的A1-A4成对代表CR1时，它们相邻的碳原子及其取代基团可以形成环B，当A5代表CR1时，A5和N—R9及其取代基团可以形成环C，或其药学上可接受的盐，在制造用于治疗和/或预防杜兴肌肉萎缩症、贝克肌肉萎缩症或消瘦症的药物中使用。
• Drug Combinations for the Treatment of Duchenne Muscular Dystrophy
  申请人：Wynne Graham Michael

  公开号：US20100168072A1

  公开（公告）日：2010-07-01

  Combinations comprising (or consisting essentially of) one or more compounds of the formula (I) or (II) with one or more ancillary compounds, to processes for preparing the combinations, and to various therapeutic uses of the combinations. Also provided are pharmaceutical compositions containing the combinations as well as a method of treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia using the combinations.

  本发明涉及由公式（I）或（II）中的一个或多个化合物与一个或多个辅助化合物组成的组合物，以及制备这些组合物的方法，以及这些组合物的各种治疗用途。还提供了含有这些组合物的药物组合物，以及使用这些组合物治疗杜氏肌营养不良症、贝克肌营养不良症或消瘦的方法。
• Isocyanato-benzotriazole und ein Verfahren zu ihrer Herstellung
  申请人：BAYER AG

  公开号：EP0235660A1

  公开（公告）日：1987-09-09

  Neue Isocyanato-benzotriazole der allgemeinen Formel in welcher R1 für einen aromatischen Kohlenwasserstoffrest steht, der gegebenenfalls mit einer Isocyanatgruppe substituiert ist und/ oder gegebenenfalls weitere, inerte Substituenten aufweist, R2, R und R4 für gleiche oder verschiedene Reste stehen und Wasserstoff oder inerte Substituenten bedeuten, sowie ein Verfahren zur Herstellung der neuen Isocyanate durch Phosgenierung der ihnen zugrundeliegenden Amino- benzotriazole bzw. ihrer Addukte mit Chlorwasserstoff oder mit Kohlendioxid.

  通式中 R1 代表芳香烃基，该芳香烃基可任选被异氰酸酯基团取代和/或任选具有进一步的惰性取代基，R2、R 和 R4 代表相同或不同的基，并表示氢或惰性取代基，以及通过使作为新异氰酸酯基础的氨基苯并三唑或其加合物与氯化氢或二氧化碳发生光固化反应制备新异氰酸酯的工艺。
• Electroluminescent device
  申请人：Ciba Holding Inc.

  公开号：EP2265092A1

  公开（公告）日：2010-12-22

  Disclosed are electroluminescent devices that comprise organic layers that contain certain 2H-benzotriazole compounds. The 2H-benzotriazole compounds are suitable components of blue-emitting, durable, organo-electrouminescent layers. The electroluminescent devices may be employed for full color display panels in for example mobile phones, televisions and personal computer screens.

  所公开的电致发光器件由含有某些 2H-苯并三唑化合物的有机层组成。这些 2H-苯并三唑化合物是蓝色发光、耐用的有机电致发光层的合适成分。电致发光器件可用于全彩显示面板，例如移动电话、电视和个人电脑屏幕。