N-氧化-n-十四烷基-N,N-二甲胺 | 3332-27-2

• 物质功能分类: 有机原料 - 氨基化合物
• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N-氧化-n-十四烷基-N,N-二甲胺
• 中文别名: N,N-二甲基十四癸胺-N-氧化物二甲基十四胺氧化物N,N-二甲基十四(烷)胺-N-氧化物；十四烷基二甲基氧化胺；N,N-二甲基十四癸胺-N-氧化物；二甲基十四胺氧化物；OA-14
• 英文名称: N,N-dimethyltetradecylamine N-oxide
• 英文别名: Myristamine oxide；N,N-dimethyltetradecan-1-amine oxide
• CAS: 3332-27-2
• 化学式: C₁₆H₃₅NO
• 分子量: 257.46
• InChiKey: ONHFWHCMZAJCFB-UHFFFAOYSA-N

物化性质

• 密度：
  0.716[at 20℃]
• 闪点：
  >100℃
• 溶解度：
  可溶解到1%的水中，透明，无色
• LogP：
  2.7 at 20℃
• 物理描述：
  Liquid
• 稳定性/保质期：
  在常温常压下，该物质保持稳定。

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2921199090
• WGK Germany：
  2
• 储存条件：
  常温、避光、通风干燥处密封保存。

SDS

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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name : N,N-Dimethyltetradecylamine N-oxide
CAS-No. : 3332-27-2
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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Section 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Skin irritation (Category 2)
Serious eye damage (Category 1)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Irritating to skin. Risk of serious damage to eyes.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal word Danger
Hazard statement(s)
H315 Causes skin irritation.
H318 Causes serious eye damage.
Precautionary statement(s)
P280 Wear protective gloves/ eye protection/ face protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s)
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S39 Wear eye/face protection.
Other hazards - none

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Formula : C16H35NO
Molecular Weight : 257,46 g/mol
Component Concentration
N,N-Dimethyltetradecylamine N-oxide
CAS-No. 3332-27-2 -
EC-No. 222-059-3

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Section 4. FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
Indication of any immediate medical attention and special treatment needed
no data available

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Section 5. FIRE-FIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Store in cool place.
Specific end uses
no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance Form: powder
Colour: white
b) Odour no data available
c) Odour Threshold no data available
d) pH 4 - 9 at 10 g/l
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point > 100 °C
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility 10 g/l at 20 °C
o) Partition coefficient: n- no data available
octanol/water
p) Autoignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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Section 10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled. Causes respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. Causes skin irritation.
Eyes Causes eye burns.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.
Additional Information
RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

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Section 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional
waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent
and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

肉豆蔻酰二甲胺氧化物是一种生物化学试剂，可用于生物材料或有机化合物的相关研究，在生命科学领域具有重要作用。

反应信息

• 作为反应物：
  描述：

  N-氧化-n-十四烷基-N,N-二甲胺 生成 1-十四烯
  参考文献：
  名称：

  DEVINSKY, FERDINAND;GORROD, JOHN W., J. CHROMATOGR., 466,(1989) C. 347-353

  摘要：

  DOI：
• 作为产物：
  描述：

  十四烷基二甲基叔胺 在 双氧水 作用下， 生成 N-氧化-n-十四烷基-N,N-二甲胺
  参考文献：
  名称：

  Production of solid tertiary amine oxides

  摘要：

  描述了一种生产具有两个甲基或乙基基团和一个稳定的长链一次脂肪族基团的三级胺氧化物的过程，其以固态形式存在。在无机溶剂的情况下，在碳酸气体存在的情况下，将水性65-90%过氧化氢和具有两个甲基或乙基基团和一个8-24碳原子的一次脂肪族烃基团的三级胺按照大约每摩尔三级胺的1.1-1.3摩尔的比例混合。当反应物中三级胺的转化为三级胺氧化物达到约60-90%时，将反应物转移到单独的容器中，然后让反应物在约20-60摄氏度的温度下凝固。该过程使得可以生产高纯度固态产品，而不会形成任何可观的不良副产物。此外，该过程环保，避免了与产品工艺、纯化、结晶和废物处理相关的问题和费用，如果不是完全避免的话也是大大减少了。此外，与液体溶液相比，固态存储稳定产品的存储和运输成本显著降低。这些产品在制造家用和商用洗衣剂配方时非常有用，这些配方以粉末或薄片的形式提供。

  公开号：

  US06121490A1
• 作为试剂：
  描述：

  methyl naphthalene-2-sulfonate 在 水 、 N-氧化-n-十四烷基-N,N-二甲胺 作用下， 生成 2-萘磺酸
  参考文献：
  名称：

  Effects of micellar head group structure on the spontaneous hydrolysis of methyl naphthalene-2-sulfonate. The role of perchlorate ion

  摘要：

  下列表面活性剂、CTAOM、n-C16H33N+Me3MeSO3– 的阳离子、阴离子和两性离子胶束可抑制 2-萘磺酸甲酯 (MeON) 在水中的自发 (SN2) 水解； CTPAOM，n-C16H33N+Pr3MeSO3–； SDS，C12H25OSO3–Na+； SB3-14, n-C14H29N+Me2(CH2)3SO3–;SBBu3-14, n-C14H29N+Bu2(CH2)3SO3–; DMMAO，n-C14H29N+Me2O–； DPMAO，n-C14H29N+Pr2O–。对于所有阳离子和两性离子胶束（包括质子化氧化胺），相对于水中速率常数 krel 的范围为 0.55-0.63。 SDS 阴离子胶束中的 krel 值为 0.22，但 NaClO4 使 SB3-14 中的 krel 从 0.56 急剧降低至 0.15。这些速率效应与底物结合的变化无关，而是取决于头基与初始和过渡态的相互作用。

  DOI：

  10.1039/a705316i

文献信息

• HAIR COLORING COMPOSITIONS
  申请人：——

  公开号：US20020032933A1

  公开（公告）日：2002-03-21

  A hair coloring composition comprising: (a) from about 0.0003 moles (per 100 g of composition) to less than about 0.09 moles (per 100 g of composition) of an inorganic peroxygen oxidizing agent; and (b) an oxidative hair coloring agent; wherein the pH of each of (a) and (b) is in the range of from about 1 to about 6 and wherein the combined mixture of (a) and (b) has a pH in the range of from about 1 to about 6. The products can provide excellent hair coloring and in-use efficacy benefits including excellent initial color and good wash fastness in combination with reduced hair damage at low pH.

  一种染发组合物，包括：(a)约0.0003摩尔（每100克组合物）至约0.09摩尔（每100克组合物）的无机过氧化氧化剂；和(b)氧化性染发剂；其中(a)和(b)的pH值在约1至约6的范围内，且(a)和(b)的混合物的pH值在约1至约6的范围内。该产品可以提供出色的染发效果和使用效果，包括出色的初始颜色和良好的耐洗性，同时在低pH值下减少头发损伤。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] GENERATION OF PEROXYHYDROXYCARBOXYLIC ACID AND THE USE THEREOF<br/>[FR] GÉNÉRATION D'ACIDE PEROXYHYDROXYCARBOXYLIQUE ET SON UTILISATION
  申请人：ECOLAB USA INC

  公开号：WO2021155078A1

  公开（公告）日：2021-08-05

  Peroxyhydroxycarboxylic acid forming compositions and methods for forming peroxyhydroxycarboxylic acids, preferably in situ, using the peroxyhydroxycarboxylic acid forming compositions are disclosed. Methods of using the peroxyhydroxycarboxylic acids, including for treating a surface or a target in need of antimicrobial or sanitizing treatment are also disclosed. Particular applications of using odor-free, low volatility peroxyhydroxycarboxylic acid sanitizers for direct food contact are disclosed.

  揭示了形成过氧羟基羧酸的组合物和形成过氧羟基羧酸的方法，优选是在原位使用形成过氧羟基羧酸的组合物。还揭示了使用过氧羟基羧酸的方法，包括用于处理需要抗菌或消毒处理的表面或目标。还揭示了使用无异味、低挥发性过氧羟基羧酸消毒剂进行直接食品接触的特定应用。
• Enhanced color deposition for hair with sequestering agents
  申请人：Unilever Home & Personal Care USA, Division of Conopco, Inc.

  公开号：US20030135935A1

  公开（公告）日：2003-07-24

  Hair coloring compositions which comprise: (A) non-nitrogenous chelating agents from the group consisting of polyphosphate; phosphonates; hydroxycarboxylates; polyacrylates; zeolite; and mixtures thereof; (B) an oxidative dye primary intermediate; and (C) an oxidative dye coupler; (D) and water are described. The present invention also relates to a method for coloring hair which comprises contacting said hair with a hair coloring composition as described above.

  描述了包括以下成分的染发配方：(A) 来自聚磷酸盐、膦酸盐、羟基羧酸盐、聚丙烯酸盐、沸石及其混合物等组成的非氮螯合剂；(B) 一种氧化染料的主要中间体；和(C) 一种氧化染料偶联剂；(D) 以及水。本发明还涉及一种染发方法，该方法包括将头发与上述描述的染发配方接触。
• Oil suspension concentrates based on a cyclohexenone oxime ether lithium salt and the use thereof as plant protection agents
  申请人：——

  公开号：US20040097374A1

  公开（公告）日：2004-05-20

  The present invention relates to oil suspension concentrates based on 2-{1-[2-(4-chlorophenoxy)propoxyimino]butyl}-3-hydroxy-5-(tetrahydrothiopyran-3-yl)cyclohex-2-enone lithium salt and certain formulation auxiliaries and to the use of the oil suspension concentrates as crop protection compositions and in particular as rice herbicides. Preferred formulation auxiliaries are mono- and/or dicarboxylic esters, for example fluid fatty acid esters, anionic surfactants of the sulfonate type, for example alkyl- and alkylarylsulfonates and also sulfosuccinates, and nonionic surfactants of the type of the nonethoxylated or ethoxylated carboxylic acids and esters of mono- or polyfunctional alcohols, for example ethoxylated fatty acids and polyoxyethylene sorbitan fatty acid esters. The oil suspension concentrates described herein are storage-stable and have excellent use properties.

  本发明涉及基于2-【1-【2-(4-氯苯氧)丙氧基亚氨基】丁基】-3-羟基-5-(四氢硫代吡喷-3-基)环己-2-酮锂盐和某些配方助剂的油悬浮浓缩物，以及将油悬浮浓缩物用作作物保护组合物，特别是稻田除草剂的用途。首选的配方助剂为单酸和/或二酸酯，例如流体脂肪酸酯，磺酸盐类型的阴离子表面活性剂，例如烷基和烷基芳基磺酸盐以及磺酸琥珀酸盐，以及非离子表面活性剂，例如非环氧化或环氧化羧酸和单醇或多醇酯，例如环氧化脂肪酸和聚氧乙烯山梨醇脂肪酸酯。本文描述的油悬浮浓缩物具有良好的储存稳定性和优异的使用性能。