3,3',4',5,5',7-hexahydroxy-2',6,6',8-tetranitroflavone | 256486-45-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,3',4',5,5',7-hexahydroxy-2',6,6',8-tetranitroflavone
• 英文别名: 3,5,7-trihydroxy-6,8-dinitro-2-(3,4,5-trihydroxy-2,6-dinitrophenyl)chromen-4-one
• CAS: 256486-45-0
• 化学式: C₁₅H₆N₄O₁₆
• 分子量: 498.23
• InChiKey: BJCCOAUQKYEGPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  35
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  331
• 氢给体数：
  6
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  3,3',4',5,5',7-hexahydroxy-2',6,6',8-tetranitroflavone 在 盐酸 、 tin 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以77%的产率得到hydrochloride of 2',6,6',8-tetramino-3,3',4',5,5',7-hexahydroxyflavone
  参考文献：
  名称：

  Chemical modification of the natural flavonoid myricetin

  摘要：

  A review is presented of our own results on the synthesis of nitro-, amino-, azo-, and bromo- derivatives of myricetin, as a result which 19 new derivatives have been obtained The compounds synthesized are of interest as substances with potential antitumoral, antimicrobial, antifungal, antioxidant, and antitubercular activities.

  DOI：

  10.1007/bf02238204
• 作为产物：
  描述：

  杨梅素 在 硝酸 作用下， 以 溶剂黄146 为溶剂， 反应 3.0h， 以77%的产率得到3,3',4',5,5',7-hexahydroxy-2',6,6',8-tetranitroflavone
  参考文献：
  名称：

  Chemical modification of the natural flavonoid myricetin

  摘要：

  A review is presented of our own results on the synthesis of nitro-, amino-, azo-, and bromo- derivatives of myricetin, as a result which 19 new derivatives have been obtained The compounds synthesized are of interest as substances with potential antitumoral, antimicrobial, antifungal, antioxidant, and antitubercular activities.

  DOI：

  10.1007/bf02238204

文献信息

• COMPOSITIONS FOR SLEEPING DISORDERS
  申请人：Chan Hsiao Chang

  公开号：US20090124627A1

  公开（公告）日：2009-05-14

  Provided herein is a method for treating, preventing, or ameliorating a disorder such as insomnia or another sleeping disorder using a composition that contains an effective amount of one or more compounds.
• US7935714B2
  申请人：——

  公开号：US7935714B2

  公开（公告）日：2011-05-03
• Chemical modification of the natural flavonoid myricetin
  作者：V. V. Polyakov

  DOI：10.1007/bf02238204

  日期：1999.1

  A review is presented of our own results on the synthesis of nitro-, amino-, azo-, and bromo- derivatives of myricetin, as a result which 19 new derivatives have been obtained The compounds synthesized are of interest as substances with potential antitumoral, antimicrobial, antifungal, antioxidant, and antitubercular activities.