1,2,3,3,3-五氟丙烯 | 2252-83-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 中文名称: 1,2,3,3,3-五氟丙烯
• 英文名称: 1,2,3,3,3-pentafluoroprop-1-ene
• 英文别名: 1,2,3,3,3-pentafluoropropene；1H-Pentafluor-propen-(1)
• CAS: 2252-83-7
• 化学式: C₃HF₅
• 分子量: 132.033
• InChiKey: DMUPYMORYHFFCT-UHFFFAOYSA-N

物化性质

• 沸点：
  -18

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 危险等级：
  GAS
• 危险品标志：
  F
• 危险品运输编号：
  UN 3163
• 海关编码：
  2903399090
• 安全说明：
  S23,S3/7,S9

反应信息

• 作为反应物：
  描述：

  1,2,3,3,3-五氟丙烯 在 0.5% Pd/C 、 alumina, fluorided 氢气 作用下， 生成 2,3,3,3-四氟丙烯
  参考文献：
  名称：

  WO2008/30440

  摘要：

  公开号：
• 作为产物：
  描述：

  六氟丙烯 在 铝-三甲胺络合物 作用下， 以 乙醚 、 氘代苯 为溶剂， 20.0 ℃ 、101.33 kPa 条件下， 反应 0.08h， 生成 1,2,3,3,3-五氟丙烯
  参考文献：
  名称：

  六氟丙烯选择性加氢脱氟化为工业上相关的氢氟烯烃

  摘要：

  六氟丙烯的对HFO-1234ze和选择性加氢脱HFO-1234yf的可以通过与单群实现的形式EH的13个氢化物3  ⋅L（E = B，Al的金属; L = SMe的2，NME 3）。化学选择性根据第13族元素的性质而变化。实验和DFT计算的结合表明，涉及氢硼化中间体的竞争性亲核乙烯基取代和加成消除机制会导致互补选择性。

  DOI：

  10.1002/adsc.201900234

文献信息

• [EN] PROCESS FOR PRODUCING 1,1,1,2-TETRAFLUOROPROPENE<br/>[FR] PROCÉDÉ DE FABRICATION DE 1,1,1,2-TÉTRAFLUOROPROPÈNE
  申请人：DAIKIN IND LTD

  公开号：WO2009084703A1

  公开（公告）日：2009-07-09

  Using hexafluoropropene (HFP) as a raw material, 1,1,1,2-tetrafluoropropene (HFC-1234yf) is obtained by hydrogenation, dehydrofluorination and distillation. In a series of reactions comprised of hydrogenating HFP to obtain 1,1,1,2,3,3-hexafluoropropane (HFC-236ea), dehydrofluorinating the HFC-236ea to obtain 1,1,1,2,3-pentafluoropropene (HFC-1225ye), hydrogenating the HFC-1225ye to obtain 1,1,1,2,3-pentafluoropropane (HFC-245eb), and dehydrofluorinating the HFC-245eb to obtain HFC-1234yf, the hydrogenations and the dehydrofluorinations are respectively carried out in the one step, and then distillation is carried out so that HFC-1234yf can be obtained. Alternately, HFC-1234yf can also be obtained by hydrogenating HFP to directly obtain HFC-245eb, and separating the HFC-245eb by distillation and dehydrofluorinating it. Thus, HFC-1234yf can be produced with a high selectivity.

  使用六氟丙烯（HFP）作为原料，通过氢化、脱氟化和蒸馏得到1,1,1,2-四氟丙烯（HFC-1234yf）。在一系列反应中，将HFP氢化得到1,1,1,2,3,3-六氟丙烷（HFC-236ea），将HFC-236ea脱氟化得到1,1,1,2,3-五氟丙烯（HFC-1225ye），将HFC-1225ye氢化得到1,1,1,2,3-五氟丙烷（HFC-245eb），然后将HFC-245eb脱氟化得到HFC-1234yf，氢化和脱氟化分别在一步中进行，然后进行蒸馏以获得HFC-1234yf。另外，也可以通过将HFP氢化直接得到HFC-245eb，然后通过蒸馏和脱氟化分离HFC-245eb来获得HFC-1234yf。因此，可以高选择性地生产HFC-1234yf。
• PROCESS FOR THE PREPARATION OF FLUORINATED COMPOUNDS
  申请人：Pigamo Anne

  公开号：US20110190554A1

  公开（公告）日：2011-08-04

  A subject-matter of the invention is a process for the preparation of 2,3,3,3-tetrafluoro-1-propene which comprises the following stages: (i) hydrogenation of hexafluoropropylene to give 1,1,1,2,3,3-hexafluoropropane; (ii) dehydrofluorination of the 1,1,1,2,3,3-hexafluoropropane obtained in the preceding stage to give 1,2,3,3,3-pentafluoro-1-propene; (iii) hydrogenation of the 1,2,3,3,3-pentafluoro-1-propene obtained in the preceding stage to give 1,1,1,2,3-pentafluoropropane; and (iv) dehydrofluorination of the 1,1,1,2,3-pentafluoropropane obtained in the preceding stage to give 2,3,3,3-tetrafluoro-1-propene. Stages (ii) and (iv) are carried out using a water and potassium hydroxide mixture with the potassium hydroxide representing between 58 and 86% by weight of the mixture and at a temperature of between 110 and 180° C.

  该发明的主题是一种制备2,3,3,3-四氟-1-丙烯的方法，包括以下阶段：(i) 将六氟丙烯氢化得到1,1,1,2,3,3-六氟丙烷；(ii) 将在前一阶段获得的1,1,1,2,3,3-六氟丙烷脱氟化得到1,2,3,3,3-五氟-1-丙烯；(iii) 将在前一阶段获得的1,2,3,3,3-五氟-1-丙烯氢化得到1,1,1,2,3-五氟丙烷；和(iv) 将在前一阶段获得的1,1,1,2,3-五氟丙烷脱氟化得到2,3,3,3-四氟-1-丙烯。阶段(ii)和(iv)使用含有氢氧化钾的水混合物进行，其中氢氧化钾在混合物中的重量百分比为58%至86%，温度在110至180°C之间。
• [EN] PROCESSES FOR REDUCING THE AMOUNT OF MONOFLUOROACETATE IN HYDROFLUOROOLEFIN PRODUCTION<br/>[FR] PROCÉDÉS PERMETTANT DE RÉDUIRE LA QUANTITÉ DE MONOFLUOROACÉTATE DANS LA PRODUCTION D'UNE HYDROFLUOROOLÉFINE
  申请人：DU PONT

  公开号：WO2010129844A1

  公开（公告）日：2010-11-11

  A process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a hydrofluorocarbon with a reactant basic aqueous solution to produce an organic phase solution containing a hydrofluoroolefin and an aqueous phase solution containing a monofluoroacetate; and (b) heating the aqueous phase solution to an effective temperature to reduce the amount of monofluoroacetate in the aqueous phase solution, wherein fluoride concentration in the aqueous phase solution is substantially high. Another process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a first batch of hydrofluorocarbon with a first batch of reactant basic aqueous solution to produce a first batch of organic phase solution containing a hydrofluoroolefin and a first batch of aqueous phase solution containing a monofluoroacetate; (b) separating the first batch of organic phase solution from the first batch of aqueous phase solution; (c) mixing a second batch of hydrofluorocarbon and a second batch of reactant basic aqueous solution with the separated first batch of organic phase solution to produce a second batch of organic phase solution containing a hydrofluoroolefin and a second batch of aqueous phase solution containing a monofluoroacetate; (d) combining the first batch of aqueous phase solution with the second batch of aqueous phase solution; and (e) heating the combined aqueous phase solutions to an effective temperature to reduce the amount of monofluoroacetate in the combined aqueous phase solutions, wherein fluoride concentration in the combined aqueous phase solutions is substantially high.

  揭示了一种减少单氟乙酸盐量的过程。该过程涉及（a）将氢氟烃与反应性碱性水溶液接触，以产生含有氢氟烯烃的有机相溶液和含有单氟乙酸盐的水相溶液；以及（b）加热水相溶液至有效温度，以减少水相溶液中的单氟乙酸盐量，其中水相溶液中的氟化物浓度相当高。还揭示了另一种减少单氟乙酸盐量的过程。该过程涉及（a）将第一批氢氟烃与第一批反应性碱性水溶液接触，以产生含有氢氟烯烃的第一批有机相溶液和含有单氟乙酸盐的第一批水相溶液；（b）将第一批有机相溶液与第一批水相溶液分离；（c）将第二批氢氟烃和第二批反应性碱性水溶液与分离的第一批有机相溶液混合，以产生含有氢氟烯烃的第二批有机相溶液和含有单氟乙酸盐的第二批水相溶液；（d）将第一批水相溶液与第二批水相溶液结合；以及（e）加热组合的水相溶液至有效温度，以减少组合的水相溶液中的单氟乙酸盐量，其中组合的水相溶液中的氟化物浓度相当高。
• PROCESS FOR DEHYDROHALOGENATION OF HALOGENATED ALKANES
  申请人：Cook George R.

  公开号：US20110269999A1

  公开（公告）日：2011-11-03

  A process for the manufacture of halogenated olefins in semi-batch mode by dehydrohalogenation of halogenated alkanes in the presence of an aqueous base such as KOH which simultaneously neutralizes the resulting hydrogen halide. During the process, aqueous base is continuously added to the haloalkane which results in better yields, lower by-product formation and safer/more controllable operation.

  一种半批次模式下制造卤代烯烃的工艺，通过在存在氢氧化钾等水性碱的情况下，对卤代烷烃进行脱卤化反应，同时中和产生的氢卤酸。在该过程中，持续向卤代烷烃中加入水性碱，可获得更高产量、降低副产物生成，并使操作更安全、更可控。
• METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUNDS
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：US20180155259A1

  公开（公告）日：2018-06-07

  Provided is an efficient method for producing a fluorine-containing compound without the need for a rectification column involving numerous stages, extractive distillation, etc. The method for producing a fluorine-containing compound includes the step of supplying a composition containing a mixture to a dehydrohalogenation step, the mixture being at least one member selected from the group consisting of mixtures of at least one fluoroolefin and at least one hydrofluorocarbon, the boiling points of which are close to each other, azeotropic mixtures of at least one fluoroolefin and at least one hydrofluorocarbon, and pseudo-azeotropic compounds of at least one fluoroolefin and at least one hydrofluorocarbon.

  提供了一种高效生产含氟化合物的方法，无需涉及多级精馏柱、萃取蒸馏等。生产含氟化合物的方法包括将含有混合物的组合物供给到脱卤化步骤，所述混合物至少包括以下群组成员之一的混合物：至少一种氟烯烃和至少一种氢氟碳化合物，其沸点接近，至少一种氟烯烃和至少一种氢氟碳化合物的共沸混合物，以及至少一种氟烯烃和至少一种氢氟碳化合物的伪共沸化合物。