山嵛酸乙酯 | 5908-87-2

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 山嵛酸乙酯
• 中文别名: 蘿酸乙酯
• 英文名称: ethyl docosanoate
• 英文别名: docosanoic acid, ethyl ester；docosanoic acid ethyl ester；ethyl ester docosanoic acid；Docosansaeure-aethylester；n-Dokosansaeure-ethylester；Docosansaeure-ethylester
• CAS: 5908-87-2
• 化学式: C₂₄H₄₈O₂
• mdl: MFCD00056275
• 分子量: 368.644
• InChiKey: JIZCYLOUIAIZHQ-UHFFFAOYSA-N

物化性质

• 熔点：
  50°C
• 沸点：
  398.93°C (rough estimate)
• 密度：
  0.8789 (rough estimate)
• 溶解度：
  氯仿（微溶）、乙酸乙酯（微溶）、甲醇（微溶）
• 碰撞截面：
  194.9 Ų [M-H]- [CCS Type: TIMS, Method: single field calibrated]
• 保留指数：
  2596;2576;2573

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  26
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.958
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090
• 危险性防范说明：
  P261,P280,P301+P312,P302+P352,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335
• 储存条件：
  应存放在室温、干燥且密封的环境中。

反应信息

• 作为反应物：
  描述：

  山嵛酸乙酯 在 copper oxide-chromium oxide 作用下， 生成 二十二烷-1-醇
  参考文献：
  名称：

  Meakins; Mulley, Australian Journal of Scientific Research, Series A: Physical Sciences, 1951, vol. 4, p. 365,367

  摘要：

  DOI：
• 作为产物：
  描述：

  芥酸 在 乙醇 、 氢气 、 溶剂黄146 作用下， 生成 山嵛酸乙酯
  参考文献：
  名称：

  Levene; Taylor, Journal of Biological Chemistry, 1924, vol. 59, p. 921

  摘要：

  DOI：

文献信息

• [EN] PROCESS FOR THE PREPARATION OF ACYLATED SECONDARY ALCOHOL ALKOXYLATES AND SECONDARY ALCOHOL ALKOXYLATES<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ALCOXYLATES D'ALCOOLS SECONDAIRES ACYLÉS ET ALCOXYLATES D'ALCOOLS SECONDAIRES
  申请人：SHELL INT RESEARCH

  公开号：WO2010049465A1

  公开（公告）日：2010-05-06

  A process for the preparation of acylated secondary alcohol alkoxylates, said process comprising : (i) reaction of one or more internal olefins with one or more carboxylic acids in the presence of a catalyst composition in order to form one or more carboxylic acid esters; (ii) reaction of one or more carboxylic acid esters from step (i) with one or more alkylene oxide reactants, in the presence of a catalytically effective amount of a catalyst composition comprising: (a) one or more alkaline earth metal salts of carboxylic and/or hydroxycarboxylic acids and/or hydrates of the former; (b) an oxy-acid selected from sulphuric acid and ortho-phosphoric acid; (c) an alcohol and/or an ester; and/or products of the reciprocal reactions of (a), (b) and/or (c) in order to form one or more acylated secondary alcohol alkoxylates; and optionally (iii) hydrolysis or transesterification of one or more acylated secondary alcohol alkoxylates from step (ii) in order to form one or more secondary alcohol alkoxylates; and a process for making secondary alcohol alkoxy sulphates comprising the steps of: preparing secondary alcohol alkoxylates by the afore-mentioned process; and sulphating the secondary alcohol alkoxylates.

  一种制备酰化二次醇烷氧基化物的方法，该方法包括：（i）在催化剂组成物的存在下，将一种或多种内部烯烃与一种或多种羧酸反应，以形成一种或多种羧酸酯；（ii）在催化剂组成物的存在下，将步骤（i）中的一种或多种羧酸酯与一种或多种烷基氧化物反应，其中催化剂组成物包括：（a）一种或多种碱土金属羧酸和/或羟基羧酸盐和/或其水合物；（b）从硫酸和正磷酸中选择的氧酸；（c）一种醇和/或一种酯和/或（a），（b）和/或（c）的互反作用产物，以形成一种或多种酰化二次醇烷氧基化物；可选地（iii）水解或酯交换步骤，以形成一种或多种二次醇烷氧基化物。制备二次醇烷氧基硫酸盐的方法包括以下步骤：通过上述方法制备二次醇烷氧基化物；并对二次醇烷氧基化物进行硫酸化。
• Measurement chip for biosensor
  申请人：——

  公开号：US20020192841A1

  公开（公告）日：2002-12-19

  The present invention provides a measurement chip for a biosensor comprising a metal surface or metal membrane treated with a compound represented by the following formula I: X—A—Y wherein X represents a heterocyclic residue comprising a —C(═O)—NH—C (═S) —NH—C (═O)-structure therein or a residue of a tautomer thereof; or a heterocyclic residue comprising a 1,3,5-triazine-2,4-dithion skeleton therein, or a residue of a tautomer thereof; A represents a divalent linking group selected from a substituted or unsubstituted amino group, an aliphatic group, an aromatic group, a heterocyclic group or a combination thereof; and Y represents a functional group capable of covalently binding to a physiologically active substance. By using this measurement chip, a substance which is a subject of measurement can be measured with high sensitivity, even if the amount of physiologically active substance immobilized is small.

  本发明提供了一种生物传感器的测量芯片，包括经化合物处理的金属表面或金属膜，该化合物由以下公式I表示：X—A—Y，其中X代表含有—C(═O)—NH—C(═S)—NH—C(═O)-结构的杂环残基或其互变异构体残基，或含有1,3,5-三嗪-2,4-二硫杂环骨架的杂环残基或其互变异构体残基；A代表选择自取代或未取代氨基、脂肪族基、芳香族基、杂环基或其组合的二价连接基团；Y代表能够与生理活性物质共价结合的功能基团。使用该测量芯片，即使固定的生理活性物质的数量很少，也能以高灵敏度测量待测物质。
• Optical resolution for producing optically active alcohol
  申请人：The Nisshin Oil Mills, Ltd.

  公开号：US05696299A1

  公开（公告）日：1997-12-09

  A process for producing an optically active alcohol comprising carrying out interesterification between a racemic alcohol and an ester selected from the group consisting of (a) a diester between a lower monohydric alcohol and a saturated dicarboxylic acid having 14 or more carbon atoms, (b) a triglyceride of a saturated fatty acid having 16 or more carbon atoms, and (c) a monoester between a lower monohydric alcohol and a saturated fatty acid having 18 or more carbon atoms in the presence of lipase, preferably heat-resistant lipase, and in the presence or absence of a solvent, preferably in the absence of a solvent, under a substantially water-free condition, separating an optically active alcohol rich in either one of R- and S-forms from the reaction mixture, and adding an optically inactive non-racemic alcohol to the residue of the previous step to carry out interesterification under the same conditions as in the previous reaction to separate the other enantiomer. According to the present invention a racemic alcohol can easily be resolved into each enantiomer with high purity in good yield.

  一种用于生产光学活性醇的方法，包括在脂肪酶的存在下，通过酯交换反应将外消旋醇和选自以下组的酯之一进行反应：（a）低级单醇和具有14个或更多碳原子的饱和二羧酸之间的双酯，（b）具有16个或更多碳原子的饱和脂肪酸的三酯，以及（c）低级单醇和具有18个或更多碳原子的饱和脂肪酸之间的单酯。最好使用耐热脂肪酶，并在存在或不存在溶剂的情况下，在基本无水的条件下进行，从反应混合物中分离出富含R-或S-形式中的一种的光学活性醇，并向前一步的残留物中添加一个光学非消旋醇，以在与前一反应中相同的条件下进行酯交换反应，以分离出另一对映异构体。根据本发明，外消旋醇可以轻松地以高纯度和良好的产率分离成每个对映异构体。
• Gall-stone dissolution compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0023375A1

  公开（公告）日：1981-02-04

  Polyol fatty acid polyesters are safe and effective agents for dissolving radiolucent gallstones when administered orally, either alone or, preferably, in conjunction with a litholytic bile acid.

  多元醇脂肪酸聚酯是安全有效的放射性胆结石溶解剂，可以单独口服，也可以与溶石胆酸一起口服。
• Pentaerythritol co-esters
  申请人：MALLINCKRODT, INC.

  公开号：EP0250087A1

  公开（公告）日：1987-12-23

  Pentaerythritol co-esters derived from pentaery­thritol, (3-alkyl-4-hydroxyphenyl)-alkanoic acids or an analog thereof and alkylthioalkanoic acids or lower alkyl esters of such acids are useful as stabilizers of organic material normally susceptible to oxidative and/or thermal deterio­ration. The co-esters are advantageously prepared by transesterification of such esters with pentaerythritol. Preferred co-esters are (I) pentaerythritol tris[3-(3,5-­di-tert-butyl-4-hydroxyphenyl)propionate]-mono[3-n-do­decylthiopropionate] and (II) pentaerythritol bis[3-­(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]-bis[3-­n-dodecylthiopropionate). The co-esters are especially useful in stabilizing applications for which physical mixtures of (i) (3-alkyl-4-hydroxyphenyl)alkanoic acid esters of polyols with (ii) polyalkanol esters of alkylthioalkanoic acids have heretofore been proposed.

  由季戊四醇、（3-烷基-4-羟基苯基）-烷酸或其类似物以及烷硫基烷酸或此类酸的低级烷基酯衍生的季戊四醇共酯可用作通常易受氧化和/或热变质影响的有机材料的稳定剂。共酯的制备方法主要是将此类酯与季戊四醇进行酯交换反应。优选的共酯类有：(I) 季戊四醇三[3-(3,5-二叔丁基-4-羟基苯基)丙酸酯]-单[3-正十二烷基硫代丙酸酯]和 (II) 季戊四醇双[3-(3,5-二叔丁基-4-羟基苯基)丙酸酯]-双[3-正十二烷基硫代丙酸酯]。这些共酯在稳定应用方面特别有用，此前已经提出了 (i) (3- 烷基-4-羟基苯基)烷酸多元醇酯与 (ii) 烷硫基烷酸多元醇酯的物理混合物。

表征谱图