五氯环丙烷 | 6262-51-7

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 环烃
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 五氯环丙烷
• 英文名称: pentachlorocyclopropane
• 英文别名: 1,1,2,2,3-pentachlorocyclopropane
• CAS: 6262-51-7
• 化学式: C₃HCl₅
• mdl: MFCD00010796
• 分子量: 214.306
• InChiKey: IACJMSLMMMSESC-UHFFFAOYSA-N

物化性质

• 沸点：
  55-56 °C/7 mmHg (lit.)
• 密度：
  1.668 g/mL at 25 °C (lit.)
• 闪点：
  213 °F
• 稳定性/保质期：

  避免与不相容材料接触。它会与强氧化剂和强碱发生反应。

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2903890090
• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P304+P340+P312,P305+P351+P338,P332+P313,P337+P313,P362,P403+P233,P405,P501
• 危险性描述：
  H315,H319,H335
• 储存条件：
  密封储存，应存放在阴凉、干燥的库房中，并远离腐蚀性物质。

SDS

Name:	Pentachlorocyclopropane 98% Material Safety Data Sheet
Synonym:
CAS:	6262-51-7

Section 1 - Chemical Product MSDS Name:Pentachlorocyclopropane 98% Material Safety Data Sheet
Synonym:

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
6262-51-7	Pentachlorocyclopropane	98.0	unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated. May cause central nervous system effects. May cause necrotic changes in the gastrointestinal tract.
Inhalation:
The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 6262-51-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 55-56C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 100 deg C ( 212.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.868
Molecular Formula: C3HCl5
Molecular Weight: 214.30

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents, strong bases.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 6262-51-7: GZ2214500 LD50/LC50:
Not available.
Not available.
Carcinogenicity:
Pentachlorocyclopropane - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 25 Avoid contact with eyes.
S 28 After contact with skin, wash immediately
with...
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 6262-51-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 6262-51-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6262-51-7 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  五氯环丙烷 在 potassium hydroxide 作用下， 反应 1.0h， 生成 四氯环丙烯
  参考文献：
  名称：

  作为潜在抗疟原虫药物的新型三环内过氧化物的设计、合成和评估†

  摘要：

  非对映选择性自动氧化允许制备新的三环内过氧化物。这些化合物及其甲基化类似物针对恶性疟原虫（一种引起疟疾的寄生虫）的体外生长进行了评估，显示出中等活性。然而，由三环过氧化物部分和 7-chloro-4-aminoquinoline 组成的杂合分子被合成并显示出抗疟原虫活性的显着增加。

  DOI：

  10.1039/c4ob00787e
• 作为产物：
  描述：

  四氯环丙烯 在 盐酸 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 生成 五氯环丙烷
  参考文献：
  名称：

  Tetrachlorocyclopropene, Tetrabromocyclopropene, and Some Fluorinated Cyclopropenes and Cyclopropanes¹

  摘要：

  DOI：

  10.1021/ja00963a023

文献信息

• [EN] TRIAMINOCYCLOPROPENIUM SALTS<br/>[FR] SELS DE TRIAMINOCYCLOPROPÉNIUM
  申请人：CURNOW OWEN JOHN

  公开号：WO2012169909A1

  公开（公告）日：2012-12-13

  Disclosed are salts comprising triaminocyclopropenium cations and various anions, and ionic liquids comprising the salts. Also disclosed are intermediates and methods of preparing the salts. The ionic liquids are useful as, for example, solvents and electrolytes, and for gas storage.

  揭示了包含三氨基环丙烯阳离子和各种阴离子的盐，以及包含这些盐的离子液体。还揭示了制备这些盐的中间体和方法。这些离子液体可用作溶剂和电解质，例如用于气体储存。
• Triaminocyclopropenium salts as ionic liquids
  作者：Owen J. Curnow、Douglas R. MacFarlane、Kelvin J. Walst

  DOI：10.1039/c1cc13979g

  日期：——

  Salts of the charge-delocalised cations of the triaminocyclopropenium (tac) family bearing alkyl substituents have been prepared and shown to be air- and water-stable ionic liquids.

  已经制备了带有烷基取代基的三氨基环丙烷（tac）家族的电荷离域阳离子的盐，并显示为空气和水稳定的离子液体。
• Synthesis and physical properties of tris(dialkylamino)cyclopropenium dicyanamide ionic liquids
  作者：Owen J. Curnow、Matthew I. J. Polson、Kelvin J. Walst、Ruhamah Yunis

  DOI：10.1039/c8ra05558k

  日期：——

  The synthesis and properties of 16 tris(dialkylamino)cyclopropenium (TDAC) cations with the dicyanamide (DCA) anion, [N(CN)2]−, are described. D3h- and C3h-symmetric cations ([C3(NR2)3]DCA (R = Me, Et, Pr, Bu, Pent, Hex, Dec) and [C3(NRMe)3]DCA (R = Bu, St), respectively) were synthesised by reaction of C3Cl5H with the corresponding amine. Reaction of the alkoxydiaminocyclopropenium salt [C3(NEt2)2(OMe)]+

  描述了 16 个三（二烷基氨基）环丙烯 (TDAC) 阳离子与双氰胺 (DCA) 阴离子 [N(CN) 2 ] -的合成和性质。D 3h - 和C 3h -对称阳离子（[C 3 (NR 2 ) 3 ]DCA (R = Me, Et, Pr, Bu, Pent, Hex, Dec) 和 [C 3 (NRMe) 3 ]DCA (R = Bu、St)、分别)通过C 3 Cl 5 H与相应的胺反应合成。烷氧基二氨基环丙烯盐[C 3 (NEt 2 ) 2 (OMe)]的反应 +与胺产生一系列C 2v对称盐 [C 3 (NEt 2 ) 2 (NR 2 )]DCA (R = Me, Bu, Hex) 和两种C s对称盐和 [C 3 (NEt 2 ) 2 (NRMe)]DCA (R = Me, Bu)。类似地，[C 3 (NMe 2 ) 2 (OMe)] +用于制备C s -对称盐 [C 3 (NMe 2
• 一种制备2,3,3,3-四氟丙烯和2-氯-3,3,3-三氟丙 烯的方法
  申请人：中化蓝天集团有限公司

  公开号：CN103896725B

  公开（公告）日：2016-01-20

  本发明公开了一种联产制备2-氯-3,3,3-三氟丙烯和2,3,3,3-四氟丙烯的方法，原料五氯环丙烷和无水氟化氢经气相氟化反应后，再经三级分离得到2-氯-3,3,3-三氟丙烯和2,3,3,3-四氟丙烯。本发明提供的制备工艺新颖，制备的2,3,3,3-四氟丙烯可替代HFC-134a用作制冷剂。
• Synthesis and physical properties of tris(dialkylamino)cyclopropenium bistriflamide ionic liquids
  作者：Kelvin J. Walst、Ruhamah Yunis、Paul M. Bayley、Douglas R. MacFarlane、Callum J. Ward、Ruomeng Wang、Owen J. Curnow

  DOI：10.1039/c5ra05254h

  日期：——

  The synthesis and properties of 23 tris(dialkylamino)cyclopropenium (TDAC) cations with the bistriflamide anion, NTf2−, are described. D3h- and C3h-symmetric cations ([C3(NR2)3]NTf2 (R = Me, Et, Pr, Bu, Pent, Hex, Dec) and [C3(NRMe)3]NTf2 (R = Et, Bu, St), respectively) were synthesised by reaction of C3Cl5H with the corresponding amine. Reaction of alkoxydiaminocyclopropenium salts ([C3(NMe2)2(OMe)]+

  合成和23三（二烷基氨基）cyclopropenium（TDAC）与bistriflamide阴离子的阳离子的性质，NTF 2 - ，中有描述。D 3h和C 3h对称阳离子（[C 3（NR 2）3 ] NTf 2（R = Me，Et，Pr，Bu，PeNT，Hex，Dec）和[C 3（NRMe）3 ] NTf 2（ R ＝ Et，Bu，St）分别通过C 3 Cl 5 H与相应的胺反应合成。烷氧基二氨基环丙烯盐（[C 3（NMe 2）2（OMe）] +和[C 3（NEt 2）2（OMe）] +）与胺反应生成两个系列的C 2v不对称盐（[C 3（NMe 2）2（NR 2）] NTf 2（R = Et，Pr， Bu，Hex）和[C 3（NEt 2）2（NR 2）] NTf 2（分别为R = Me，Bu，Hex））和两个系列的C s-对称盐（[C 3（NMe 2）2（NRMe）] NTf 2（R =

表征谱图